31,113 research outputs found

    Intellectual property law in China Max Planck series on Asian intellectual property law./ by Peter Ganea, Danny Friedmann, Jyh-An Lee, Douglas Clark ; edited by Christopher Heath.

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    "Max Planck Institute for Innovation and Competition"Includes bibliographical referencesIntroduction / Peter Ganea & Danny Friedmann -- Patents, utility models and designs / Peter Ganea -- Trade marks and related rights / Danny Friedmann -- Copyright / Peter Ganea -- Unfair competition and antitrust law / Jyh-An Lee -- Technology transfer / Jyh-An Lee -- Enforcement / Douglas Clark1 online resource (xxi, 528 pages

    The subzero microbiome: Microbial activity in frozen and thawing soils

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    Most of the Earth's biosphere is characterized by low temperatures (<5 °C) and cold-adapted microorganisms are widespread. These psychrophiles have evolved a complex range of adaptations of all cellular constituents to counteract the potentially deleterious effects of low kinetic energy environments and the freezing of water. Microbial life continues into the subzero temperature range, and this activity contributes to carbon and nitrogen flux in and out of ecosystems, ultimately affecting global processes. Microbial responses to climate warming and in particular, thawing of frozen soils are not yet well understood although the threat of microbial contribution to positive feedback of carbon flux is substantial. To date, several studies have examined microbial community dynamics in frozen soils and permafrost due to changing environmental conditions, and some have undertaken the complicated task of characterizing microbial functional groups and how their activity changes with changing conditions, either in situ or by isolating and characterizing macromolecules. With increasing temperature and wetter conditions microbial activity of key microbes and subsequent efflux of greenhouse gases also increase. In this review, we aim to provide an overview of microbial activity in seasonally frozen soils and permafrost. With a more detailed understanding of the microbiological activities in these vulnerable soil ecosystems, we can begin to predict and model future expectations for carbon release and climate change.Peer reviewe

    Glycine max "Lee" genome sequencing and assembly

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    The aims of this project were to generate a high-quality reference genome assembly for soybean cultivar "Lee," an important southern cultivar that was released in 1958 and used as a parent in many subsequent southern soybean varieties. The assembly incorporates PacBio and Illumina sequence and optical mapping from NRGene. Pseudomolecule anchoring of scaffolds was accomplished using two dense genetic maps as well as synteny comparisons with Glycine max reference assembly for cultivar Williams 82 and Glycine soja PI PI483463

    Max Baucus and Lee Metcalf

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    Max Baucus speaking with Senator Lee Metcalf.https://scholarworks.umt.edu/baucus_photographs/1004/thumbnail.jp

    An Improved Quantum Max Cut Approximation via Maximum Matching

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    Finding a high (or low) energy state of a given quantum Hamiltonian is a potential area to gain a provable and practical quantum advantage. A line of recent studies focuses on Quantum Max Cut, where one is asked to find a high energy state of a given antiferromagnetic Heisenberg Hamiltonian. In this work, we present a classical approximation algorithm for Quantum Max Cut that achieves an approximation ratio of 0.595, outperforming the previous best algorithms of Lee [Eunou Lee, 2022] (0.562, generic input graph) and King [King, 2023] (0.582, triangle-free input graph). The algorithm is based on finding the maximum weighted matching of an input graph and outputs a product of at most 2-qubit states, which is simpler than the fully entangled output states of the previous best algorithms

    Max Roybal

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    Max Roybal making wood carving

    Lee-Carter mortality forecasting: a multi-country comparison of variants and extensions

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    We compare the short- to medium-term accuracy of five variants or extensions of the Lee-Carter method for mortality forecasting. These include the original Lee-Carter, the Lee-Miller and Booth-Maindonald-Smith variants, and the more flexible Hyndman-Ullah and De Jong-Tickle extensions. These methods are compared by applying them to sex-specific populations of 10 developed countries using data for 1986-2000 for evaluation. All variants and extensions are more accurate than the original Lee-Carter method for forecasting log death rates, by up to 61%. However, accuracy in log death rates does not necessarily translate into accuracy in life expectancy. There are no significant differences among the five methods in forecast accuracy for life expectancy.Functional data, Lee-Carter method, mortality forecasting, nonparametric smoothing, principal components, state space.

    Personal Papers (MS 80-0002)

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    Letter from Max Vogan to R. Lee Kempner summoning him to the School Administration Building to discuss a change in taxes on his property

    Novel Reductive Dehalogenases from the Marine Sponge Associated Bacterium Desulfoluna spongiiphila

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    Desulfoluna spongiiphila strain AA1 is an organohalide respiring bacterium, isolated from the marine sponge Aplysina aerophoba, that can use brominated and iodinated phenols, in addition to sulfate and thiosulfate as terminal electron acceptors. The genome of Desulfoluna spongiiphila strain AA1 is approximately 6.5 Mb. Three putative reductive dehalogenase (rdhA) genes involved in respiratory metabolism of organohalides were identified within the sequence. Conserved motifs found in respiratory reductive dehalogenases (a twin arginine translocation signal sequence and two iron-sulfur clusters) were present in all three putative AA1 rdhA genes. Transcription of one of the three rdhA genes was significantly upregulated during respiration of 2,6-dibromophenol and sponge extracts. Strain AA1 appears to have the ability to synthesize cobalamin, the key cofactor of most characterized reductive dehalogenase enzymes. The genome contains genes involved in cobalamin synthesis and uptake and can grow without cobalamin supplementation. Identification of this target gene associated with debromination lays the foundation for understanding how dehalogenating bacteria control the fate of organohalide compounds in sponges and their role in a symbiotic organobromine cycle. In the sponge environment, D. spongiiphila strain AA1 may thus take advantage of both brominated compounds and sulfate as electron acceptors for respiration.Peer reviewe

    Who Was Edmund Lee?

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    Local author Peggy Donoho discusses her pioneer ancestor, Edmund Lee, and her work to preserve their family cemetery
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