1,720,988 research outputs found

    A potential pro-arrhythmic mechanism of energy drinks (eLetter to Fletcher, Emily A., Lacey, Carolyn S., Aaron, Melenie, Kolasa, Mark, Occiano, Andrew, Shah, Sachin A., "Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters", Journal of the American Heart Association, 6, 5, 2017)

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    We have read with great interest the paper “Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters” by Fletcher and coworkers and we found their conclusion of importance with a view to clinical prevention of arrhythmias in young people

    Response to Environmental impact of cardiovascular healthcare

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    Importance: The healthcare sector is essential to human health and well-being, yet its significant carbon footprint contributes to climate change-related threats to health. Objective: To review systematically published studies on environmental impacts, including carbon dioxide equivalent (CO2e) emissions, of contemporary cardiovascular healthcare of all types, from prevention through to treatment. Evidence review: We followed the methods of systematic review and synthesis. We conducted searches in Medline, EMBASE and Scopus for primary studies and systematic reviews measuring environmental impacts of any type of cardiovascular healthcare published in 2011 and onwards. Studies were screened, selected and data were extracted by two independent reviewers. Studies were too heterogeneous for pooling in meta-analysis and were narratively synthesised with insights derived from content analysis. Findings: A total of 12 studies estimating environmental impacts, including carbon emissions (8 studies), of cardiac imaging, pacemaker monitoring, pharmaceutical prescribing and in-hospital care including cardiac surgery were found. Of these, three studies used the gold-standard method of Life Cycle Assessment. One of these found the environmental impact of echocardiography was 1%-20% that of cardiac MR (CMR) imaging and Single Photon Emission Tomography (SPECT) scanning. Many opportunities to reduce environmental impacts were identified: carbon emissions can be reduced by choosing echocardiography as the first cardiac test before considering CT or CMR, remote monitoring of pacemaker devices and teleconsultations when clinically appropriate to do so. Several interventions may be effective for reducing waste, including rinsing bypass circuitry after cardiac surgery. Cobenefits included reduced costs, health benefits such as cell salvage blood available for perfusion, and social benefits such as reduced time away from work for patients and carers. Content analysis revealed concern about the environmental impact of cardiovascular healthcare, particularly carbon emissions and a desire for change. Conclusions and relevance: Cardiac imaging, pharmaceutical prescribing and in-hospital care including cardiac surgery have significant environmental impacts, including CO2e emissions which contribute to climate-related threats to human health. Importantly, many opportunities to effectively reduce environmental impacts exist within cardiac care, and can provide economic, health and social cobenefits

    Nutrition and prevention of venous thromboembolism

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    Prophylaxis of venous thromboembolism is a major health problem in everyday clinical practice. The therapeutic anticoagulants available to clinicians for prophylaxis of VTE is mainly composed by parenteral anticoagulants and oral vitamin K antagonists, warfarin. Oral vitamin K antagonists have several limitations, including a narrow therapeutic window and a metabolism that is affected by multiple drug and herbal interactions, vitamin K intake and genetic polymorphisms. The present review explore causes of poor prevention of thromboembolism and evaluated some new anticoagulants. The main target of new anticoagulants is to replace oral vitamin K antagonists for long-term anticoagulation. Moreover the role of genetics and the novel concept of cell therapy is evaluated. The hypothesis is that the patho-physiology of thrombosis may involve a "physiologic" cell that provides the same repair molecules that are used for treatment of thrombotic disorders

    Dark chocolate could prevent pre-clinical atherosclerosis

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    We have read with great interest the paper “Effects of Dark Chocolate and Almonds on Cardiovascular Risk Factors in Overweight and Obese Individuals: A Randomized Controlled-Feeding Trial” by Lee and coworkers [1] and we found their results of importance in the field of clinical prevention. Authors demonstrate that consumption of almonds alone or combined with dark chocolate under controlled feeding conditions improves lipid profiles. Incorporating almonds, dark chocolate, and cocoa into a typical American diet without exceeding energy needs may reduce the risk of coronary heart diseas

    The Influence of Health on Gross Domestic Product and National Income

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    It is beyond question how the Gross Domestic Product (GDP) and the other National Income and Product Accounts (NIPA) have been groundbreaking in the economic studies and researches of the last century, nevertheless they are often targets of criticism as a result of their failure in including non-market activities in their estimates. Since the beginning of the last century the technophysio evolution has enabled a fivefold increase of the average retirement period, an increase of seven times of the portion of individuals who lives to retire and a fourfold increase of the leisure time of those who are still in the labor force

    Response to: A fifth of surgeons in England are female

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    During the last decade, the percentage of women graduates in medicine has increased considerably, in Italy and Europe, and therefore inevitably also those who specialize in general surgery and specialized branches. The data provided by the Statistical Office of the Ministry of Education of the University and Research (MIUR) for the academic year 2014/2015 show that 45.3% of those enrolled in schools of specialization in general surgery are women

    Bacteremia in Cardiac Surgery Patients with Heparin-Induced Thrombocytopenia

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    We have read with great interest the paper "Characterization of hospitalized cardiovascular patients with suspected heparin-induced thrombocytopenia" by Stoll and co-workers [1] and we found it very important with a view to clinical prevention

    Fruit and vegetables in hypertensive women with asymptomatic peripheral arterial disease

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    Background and aims: Fruit and vegetables are considered a very healthy diet useful in the prevention of cardiovascular disease. The present study aims to evaluate intake of fruit and vegetables in hypertensive women and its correlation with asymptomatic atherosclerosis. Methods and results: A group of 237 women with hypertension was evaluated. Fruit and vegetables consumption were assessed by a self-administered food frequency validated questionnaire completed by an interviewer administered 24 h diet recall. They all underwent ABI. ABI measurement observed that fruit consumption was inversely associated with pre-clinical atherosclerosis suggesting a protective effect, moreover this association was stronger for vegetables. Increasing intake of vegetables was associated with a lower risk of asymptomatic PAD. Conclusions: Women with a high intake of fruit and vegetables showed less instrumental sign of preclinical peripheral atherosclerosis. Can be suggests that fruit and vegetables play an important role in prevention of atherosclerosis in pre-menopausal women

    Effects of early treatment with zofenopril in patients with myocardial infarction and metabolic syndrome: the SMILE Study

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    To evaluate the clinical efficacy of the early administration of zofenopril in a group of patients with and without metabolic syndrome (MS+ and MS-) and anterior myocardial infarction enrolled in the Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study
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