1,721,284 research outputs found
Effects of caffeine and coffee consumption on cardiovascular disease and risk factors
No full textIn recent years, clinical and observational studies reported that coffee consumption was associated with cardiac arrhythmia, with increased in serum cholesterol and blood pressure and affected heart rate variability, and subsequently increased cardiovascular risk. The analysis of these paper shows that data are controversial and strongly depends on methodology. Recent reports underline the beneficial effects of coffee consumption due to anti-inflammatory actions mediated by antioxidant compound of the beverages
Espresso coffee, caffeine and colon cancer
Full text linkIn this letter we contribute to discussion on Caffeine and its main targets of colorectal cancer. We evaluated the impact of espresso coffee intake in patients with colorectal cancer and we analyzed gender differences. The hypothesis is that espresso coffee adds some antioxidants substances that contribute to total antioxidants in a healthy diet. We explore a Mediterranean population that has a diet rich in antioxidants, with high intake of fruit and vegetables
Commentary on "Is vitamin D deficiency a more frequent finding in hirsutism or not?"
No full textDear Editor,
I am writing to provide commentary on the recent article by Eftekhari et al., Is vitamin D deficiency a more frequent finding in hirsutism or not?, which investigates vitamin D levels in women with and without hirsutism. This study addresses an important area of research, as hirsutism, often associated with polycystic ovary syndrome (PCOS) and hyperandrogenism, intersects with broader metabolic and cardiovascular risks [1]
Pharmacotherapy of pulmonary embolism.
No full textPulmonary embolism (PE) and deep vein thrombosis are common causes of illness and death. The pharmacological approach to pulmonary embolism includes the use of anticoagulants, unfractionated heparin for the acute phase, and oral anticoagulants for prophylaxis. In massive PE, the use of thrombolytic agents is suggested to reduce systemic hypotension and right ventricular failure and increase cardiac output. Thrombolytic agents act on pulmonary vascular obstruction. In clinical practice, thrombolytic therapy is recommended in case of massive embolism with haemodynamic failure. Recent studies suggest the use of thrombolytic drugs in patients with normal systemic blood pressure who show right ventricular dysfunction at echocardiographic examination. A large randomised trial on lytic agents in submassive PE is therefore needed. Anticoagulants were primarily indicated for prevention of recurrences. Due to the development of low molecular weight heparin, the role of anticoagulants needs to be re-evaluate
La trombocitopenia da eparina: implicazioni per il cardiologo.[Heparin-induced thrombocytopenia: implications for cardiologist]
No full textHeparin-induced thrombocytopenia (HIT) is one of the most life-threatening adverse effects of heparin administration. It is characterized by thrombocytopenia and may also be associated with venous or arterial thrombosis. HIT type 2 is caused by the binding of antibodies, most likely IgG, to a complex of heparin and platelet factor-4, these complexes IgG/PF4/heparin activate platelets causing the release of pro-thrombotic particles that promote thrombin generation. HIT and HIT-thrombosis are associated with high morbidity and mortality. Thrombotic events are most frequently venous and may manifest as pulmonary embolism or cerebral venous thrombosis. Arterial thrombosis leading to limb damage and amputation and to myocardial infarction or stroke may also occur. HIT is a clinical syndrome that requires clinical and laboratory findings to confirm the diagnosis. All forms of heparin treatment should be stopped once HIT is suspected and patients should be treated with an alternative anticoagulant to treat and prevent thrombotic complications. Available alternative anticoagulants include argatroban and lepirudin, a recombinant form of hirudin
Link between coffee and atrial fibrillation debunked?
Full text linkThe relationship between atrial fibrillation (AF) and coffee is
controversial, although it carries important clinical implications
due to the fact that caffeine is one of the most widely
consumed active substances in the world and that AF is the
most common arrhythmia in adults
La trombocitopenia da eparina: implicazioni per il cardiologo.[Heparin-induced thrombocytopenia: implications for cardiologist]
No full textHeparin-induced thrombocytopenia (HIT) is one of the most life-threatening adverse effects of heparin administration. It is characterized by thrombocytopenia and may also be associated with venous or arterial thrombosis. HIT type 2 is caused by the binding of antibodies, most likely IgG, to a complex of heparin and platelet factor-4, these complexes IgG/PF4/heparin activate platelets causing the release of pro-thrombotic particles that promote thrombin generation. HIT and HIT-thrombosis are associated with high morbidity and mortality. Thrombotic events are most frequently venous and may manifest as pulmonary embolism or cerebral venous thrombosis. Arterial thrombosis leading to limb damage and amputation and to myocardial infarction or stroke may also occur. HIT is a clinical syndrome that requires clinical and laboratory findings to confirm the diagnosis. All forms of heparin treatment should be stopped once HIT is suspected and patients should be treated with an alternative anticoagulant to treat and prevent thrombotic complications. Available alternative anticoagulants include argatroban and lepirudin, a recombinant form of hirudin
Coffee consumption effects on bioelectrical impedance parameters: does gender matter?
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