114,838 research outputs found

    Joshua Davis: Author of Spare Parts

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    Citation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University

    Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation-enriched CCCH protein

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    The regulation of differentiation is particularly important in microbial eukaryotes that inhabit multiple environments. The parasite Trypanosoma brucei is an extreme example of this, requiring exquisite gene regulation during transmission from mammals to the tsetse fly vector. Unusually, trypanosomes rely almost exclusively on post-transcriptional mechanisms for regulated gene expression. Hence, RNA binding proteins are potentially of great significance in controlling stage-regulated processes. We have previously identified TbZFP1 as a trypanosome molecule transiently enriched during differentiation to tsetse midgut procyclic forms. This small protein (101 amino acids) contains the unusual CCCH zinc finger, an RNA binding motif. Here, we show that genetic ablation of TbZFP1 compromises repositioning of the mitochondrial genome, a specific event in the strictly regulated differentiation programme. Despite this, other events that occur both before and after this remain intact. Significantly, this phenotype correlates with the TbZFP1 expression profile during differentiation. This is the first genetic disruption of a developmental regulator in T. brucei. It demonstrates that programmed events in parasite development can be uncoupled at the molecular level. It also further supports the importance of CCCH proteins in key aspects of trypanosome cell function

    Steven Johnson Author Talk Poster

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    K-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book

    Entrevista a Leah Matthews

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    REMOTE: Assessing and evaluating remote learning practices in STEM, projecte Erasmus finançat en el marc del programa Erasmus+; Projecte: Grant Agreement number: 2022-1-ES01-KA220-HED-000085829Dr. Leah K. Matthews, Executive Director & Chief Executive Officer of the DEAC -Washington DC, answers the following questions: 1. How do you imagine the university of the future?, a. What teaching and assessment methodologies do you mostly imagine? b. What learning technologies do you think will prevail?; 2. How will the students of the future be different from those of today? (demands, expectations,...); 3. How will online / remote assessment methodologies affect learning practices in STEM, differently depending on… a. the gender? (students / faculty) b. the studies typology?, Will it be different in STEM studies from the rest? and 4. How will professors teach in a future paradigm focused on learning skills and abilities instead of knowledge?7117_01.mp4 7117_01.mp3 7117_02.mp4 7117_02.mp3 7117_03.mp4 7117_03.mp3 7117_04.mp4 7117_04.mp

    Frank Stanger, Bishop James K and Eunice Matthews (Sept 4 1980)

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    Frank Stanger, Bishop James K and Eunice Matthews (Sept 4 1980). James K Matthews was a United Methodist Bishop who had worked in India. He married Eunice Matthews who was the daughter of E. Stanley Jones.https://place.asburyseminary.edu/atshistory/1053/thumbnail.jp

    Frank Stanger, Bishop James K and Eunice Matthews (Sept 4 1980)

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    Frank Stanger, Bishop James K and Eunice Matthews (Sept 4 1980). James K Matthews was a United Methodist Bishop who had worked in India. He married Eunice Matthews who was the daughter of E. Stanley Jones.https://place.asburyseminary.edu/atshistory/1054/thumbnail.jp

    George Matthews, in a white coat on left, overseeing the refueling of a de Havilland DH53 Humming Bird in front of the Matthews Aviation hangar, Commonwealth Aerodrome, Essendon, Victoria, 1925 [picture].

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    Title devised by cataloguer based on caption list.; Part of the George Matthews collection of aviation photographs, 1925-1939.; Inscriptions: "G Matthews - White coat, K Gardiner in plane, DH Hummi, Essendon, 1925"--In blue ink on verso.; Condition: Tears.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4856024. Aeroplanes from left to right: de Havilland DH53 Humming Bird being refueled; de Havilland DH9 partially disassembled in hangar; Avro 504 with long range fuel tanks on top of the wings; de Havilland DH60 Moth on left

    A Saunders Roe A17 Cutty Sark amphibious aeroplane parked in front of the Matthews Aviation hangar, Essendon, Melbourne, Victoria, ca. 1934 [picture].

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    Title devised by cataloguer based on inscription.; Part of the George Matthews collection of aviation photographs, 1925-1939.; Inscriptions: ""Cutty Sark" Flying Boat belonging to Matthews Aviation which arrived by the "Ballarat" yesterday. To be put into operation in experimental work between Victoria and Tasmania. Fuel arrangements by Shell Company."--Typed on verso; "Reproduced by, K. Hume, Commercia Photographer, 402 P.O. Place, Melbourne, C1"--Stamp on verso.; Condition: Tears.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4854271
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