3,335 research outputs found
James M. Sweet Correspondence
No full textEntries include a typed introductory letter to Sweet about the Maine Author Collection from the Maine State Library, a typed letter of presentation from Sweet, a typed biography Facts About Me concerning his published works, collecting used sets of encyclopedias, the supernatural, and poetic correspondence with U.S. soldiers in Vietnam, and a typed composition with reference to gospel tracts, songs, and a diary written by Sweet, in response to film and theater productions of A Streetcar Named Desire
Anna Kavan - Free Thinking, BBC Radio 3
No full textAsylum and psychiatric institutions, obsession and heroin, and imagining a new self are explored in the writing of Anna Kavan (1901-1968). With the republication of her novel Ice and a series of artists and musicians exploring her work, her reputation is now on the rise. Matthew Sweet is joined by critic and author Chris Power, Carole Sweeney, who researches experimental fiction, Sally Marlow, who studies the psychology of addiction and is Radio 3’s researcher in residence, and the literary scholar Victoria Walker, who founded the Anna Kavan Society
Sweeteners, sweet antagonists, and metabolism
No full textSugars and sweeteners are proposed to stimulate human sweet taste via the receptor, T1R2-T1R3. T1R2-T1R3 is a heterodimeric GPCR expressed in oral taste tissue. T1R2-T1R3 binds sugars, non-nutritive sweeteners, and sweet taste blockers. It was recently discovered that T1R2-T1R3 is also expressed in extra-oral tissues including the intestine, hypothalamus, pancreas, and adipose. This finding is striking because non-nutritive sweeteners are believed to be metabolically inert. Hence, it raises the question of whether T1R2-T1R3 plays a role not only sweet taste perception but also in regulatory and metabolic physiology. The purpose of this research project is to investigate the perceptual and physiological functions of T1R2-T1R3 using a pharmacological approach in human participants. In the first aim, I determined whether glucose and fructose behave as partial agonists of the sweet taste receptor and can enhance or suppress each other in mixture. In the second aim, I sought to assess and improve the sweetness of glucose and its metabolic profile relative to fructose and sucrose. In the third aim, I conducted psychophysical studies to determine whether metabolically active drugs act on the sweet taste receptor. In the fourth aim, I conducted glucose tolerance studies to determine whether sweet taste stimuli influence glucose metabolism. And in the fifth aim, I conducted glucose tolerance tests to determine whether sweet taste inhibitors influence glucose metabolism. I found that sweeteners and antagonists had both perceptual and physiological functions. In the first aim, I demonstrated that glucose is a poor sweetener relative to fructose because it is not a full agonist of the sweet receptor. In the second aim, I demonstrated that glucose can be rendered almost indistinguishable from sucrose at the same caloric level with the addition of a non-nutritive sweetener. Thus, the difference in glucose and fructose sweetness can be overcome when adding stevioside to glucose. In the third aim, I demonstrated that clofibric acid, a lipid lowering prescription drug, inhibits sweet taste perception. Since it has been shown to inhibit T1R3 in vitro, I conclude from our data that it is also a T1R3 inhibitor in vivo. In the fourth aim, I demonstrated that high potency sweeteners (HPS), which are thought to be metabolically inert, enhance insulin and glucose responses relative to a standard OGTT. And in the fifth aim, I found that sweet taste blockers caused an opposite reaction and slowed glucose rise in the blood relative to a standard OGTT. As a sugar receptor, T1R2-T1R3 imparts a powerful influence on human health by guiding food choice and metabolism. My findings are of public health relevance because excessive intake of sweet tasting compounds such as sugars and other sweeteners are a major long-term health concern. Overconsumption of dietary sugars, particularly in the form of sweetened beverages, is thought to promote obesity, diabetes, fatty liver disease, and metabolic syndrome. Despite efforts to curb intake of sweet beverages, the typical American consumes 50 liters of caloric and non-caloric soft drinks per year and even more in sugar-added foods and confections. As the prevalence of metabolic diseases grows, there is a greater need to understand the perceptual and physiological mechanisms, drives, and responses for sweet tasting compounds.Ph.D.Includes bibliographical referencesby Matthew C. Koche
Surface impoundment assessment for the State of Oregon: report to the Environmental Protection Agency
No full textThis archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from cover."The Environmental Protection Agency (EPA) undertook the nationwide Surface Impoundment Assessment (SIA) in order to locate and assess natual or man-made pits, ponds, or lagoons whose intended purpose the treatment, storage and/or disposal of liquid waste. An evaluation of potential ground-water contamination was the primary goal"--Page 1-1.Includes bibliographical references."The SIA progam in Oregon was conducted by Sweet, Edwards and Associates under contract to Oregon Department of Environmental Quality".Mode of access: Internet from the Oregon Government Publications Collection.Text in English
What makes a cherry red?: an investigation into flavonoid pathway regulation in sweet cherry (Prunus avium L.) fruit.
No full textColour is an important fruit quality indicator because many consumers make their selections based primarily on this trait. Inheritance of colour has been studied within sweet cherry (Prunus avium L.) populations and as a result fruit colour is thought to be determined by three genetic factors. A flesh colour factor (F) and the major skin colour factor (A) are the main determinants of fruit colour, where red pigmentation is incompletely dominant over yellow. A third factor, the minor skin colour factor (B), can produce blush skin but is epistatically masked by a dominant A allele. The pigments that colour fruit are known as anthocyanins, synthesised via the transcriptionally regulated flavonoid pathway, which also synthesizes the related secondary metabolites, condensed tannins and flavonols. In other fruit and flower species, mutations in flavonoid pathway or regulatory genes can lead to non-functional alleles that explain the inheritance of colour. However the genes encoding the genetic colour factors are not known in sweet cherry. Therefore, this research has endeavoured to study the cherry flavonoid pathway and its transcriptional regulation, with a view to determining the genetic differences responsible for yellow, blush, red and black cultivars. To achieve this aim, genes encoding flavonoid pathway enzymes and putative regulators of flavonoid synthesis were isolated from the red sweet cherry cultivar ‘Lapins’. PaMYBA1, an R2R3-MYB factor, possessing a high degree of sequence similarity with characterised anthocyanin regulators and conserved C-terminal motifs common within this type of protein, was identified. Functional characterisation of PaMYBA1 demonstrated its ability to activate transcription from the promoters of chalcone synthase (MdCHS), which encodes an enzyme that performs the first committed step in the synthesis of flavonoids, and the anthocyanin biosynthetic gene UDP-glycosyl:flavonoid-3-O-glycosyltransferase (MdUFGT). Furthermore, correlation between anthocyanin accumulation and the expression profile of PaMYBA1 in developing ‘Lapins’ fruit and light-treated blush-skinned ‘Ranier’ fruit suggest that PaMYBA1 might be an important colour factor. Transcript analysis revealed that PaMYBA1 is necessary for the production of colour in cherries; PaMYBA1 is not expressed in the solid yellow fruit of ‘Yellow Glass’ that lacks anthocyanins. However, similar levels of expression of PaMYBA1 in blush, red and black sweet cherry fruit indicate that there are additional factors that contribute to differences in colour intensity. The intense colour and increased flavonoid levels of the black sweet cherry ‘Sam’, compared with the blush and red fruits tested, correlated with a large increase in the expression of the putative tannin regulator PaMYBPA1 in this cultivar. In a functional assay, PaMYBPA1 could trans-activate not only the promoters of the tannin genes anthocyanidin reductase (VvANR) and leucaonthocyanidin reductase (VvLAR), but also of MdCHS and MdUFGT. Therefore, it is possible that PaMYBPA1 could regulate both tannin and anthocyanin synthesis, particularly when expressed at high levels. Taking into consideration the expression of flavonoid pathway genes in different sweet cherry cultivars and tissues, and under different environmental conditions, together with published scientific observations of the genetic factors contributing to fruit colour, we have developed a working model for flavonoid pathway regulation in sweet cherry fruit. Aspects of the model remain to be determined, such as the involvement of two additional anthocyanin-type MYB factors PaMYBA2 and PaMYBA3 in fruit pigmentation. However, it provides a general understanding of differences in the activity of the flavonoid pathway between sweet cherry cultivars, and moves us closer to knowing the identity of the inherited factors that determine skin and flesh colour in sweet cherry fruit.Thesis (Ph.D) -- University of Adelaide, School of Agriculture, Food and Wine, 201
4-dimensional homogenous algebras
No full textPT: J; CR: ARTAMONOV VA, 1977, MATH USSR SB, V33, P375 DJOKOVIC DZ, 1973, P AM MATH SOC, V41, P457 GROSS F, 1972, P AM MATH SOC, V31, P10 IVANOV DN, 1982, VESTNIK MOSKOV U MAT, V37, P69 KOSTRIKIN AI, 1965, IZVESTIYA AKAD NAUK, V29, P471 MACDOUGALL JA, 1978, PAC J MATH, V74, P153 SHULT EE, 1969, ILLINOIS J MATH, V13, P625 SWEET LG, 1975, P AM MATH SOC, V48, P321 SWEET LG, 1975, PAC J MATH, V59, P585 SWEET LG, 1986, CANAD MATH B, V29, P224; NR: 10; TC: 2; J9: PAC J MATH; PG: 9; GA: K3230Source type: Electronic(1
Collegium Musicum, April 1, 1987
No full textRecorded during a live performance at Dalton Center Lecture Hall, Western Michigan University, Kalamazoo, Michigan, April 1, 1987, 8:00 p.m., the 298th concert of the School of Music's 1986-1987 season.Collegium Musicum ; Matthew Steel, director.Vocal works sung in Middle English, English, and Latin.Information from performance program.Medieval England: -- Worldes blis ne last no throwe / Anonymous, early 13th cetnury -- English dance / Anonymous, 13th century -- Miri it is while sumer ilast / Anonymous, c. 1230 -- Foweles in the frith / Anonymous, ca. 1240 -- Summer is icumen in / Anonymous, ca. 1240 -- Early Renaissance: -- O potores exquisiti / Anonymous, before 1450 -- Tappster dryngker / Anonymous, 15th century -- Now wolde y fayne / Anonymous, mid-15th century -- Puzzle canon / Robert Fayrfax -- O my hart / Henry VIII -- Ah Robin, gentle Robin / William Cornysh -- I love unloved / Anonymous, early 15th century -- Late Renaissance: -- Venus' birds / John Bennet -- The dark is my delight / Anonymous, ca. 1600 -- Fantasy for two cornetts and sackbut / John Hingeston -- Bonny sweet Robin / Giles Farnaby? -- Ricercar, Bonny sweet Robin / Thomas Simpson
Prostitúció és a Viktoriánus Sztereotípiák Újraértelmezése Matthew Kneale Sweet Thames és Faye L. Booth Trades of the Flesh Regényeiben
No full textThe two chosen contemporary novels, Matthew Kneale’s Sweet Thames and Faye L. Booth’s Trades of the Flesh represent women from different point of view, not the well-known Victorian gender stereotypes. The works recycle the typical Victorian stereotypes of femininity, including the figure of the prostitute and the middle-class wife but they also question them.AnglisztikaBs
Algebras with transitive automorphism groups
No full textPT: J; CR: GOLOMB SW, 1969, COMBINATORIAL MATH I GROSS F, 1972, P AM MATH SOC, V31, P10 IVANOV DN, 1982, VESTNIK MOSKOV U MAT, V37, P69 KOSTRIKIN AI, 1965, IZVESTIYA AKAD NAUK, V29, P471 SHULT EE, 1969, ILLINOIS J MATH, V13, P625 SIMMONS GJ, 1970, AM MATH MONTHLY, V77, P743 SWEET L, 1975, CANAD MATH B, V17, P723 SWEET LG, 1975, P AM MATH SOC, V48, P321; NR: 8; TC: 1; J9: CAN MATH BULL-BULL CAN MATH; PG: 3; GA: C9332Source type: Electronic(1
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