58 research outputs found

    Automated Sample Ratio Mismatch (SRM) Detection and Analysis

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    Background: Sample Ratio Mismatch (SRM) checks can help detect data quality issues in online experimentation [3]. Not all experimentation platforms provide these checks as part of their solution. Users of these platforms must therefore manually check for SRM, or rely on additional processes—such as checklists [2]—or automation. Objective: To ensure reliable and early detection of SRM, we wanted to automate the detection and analysis of SRM in experiments running on third-party experimentation platforms. Method: A set of Looker dashboards were built to facilitate self-serve SRM detection and root cause analysis. In addition, we added email and chat based alerting to pro-actively inform experimenters of SRM and guide them towards these dashboards when needed. Results: Several cases of SRM have been detected and experimenters have been warned. Bad decisions based on flawed data were avoided. We provide one such example as an illustration. Conclusions: SRM checks are relatively straightforward to automate and can be useful for data quality monitoring even for companies who rely on third-party experimentation platforms. Pro-active alerting—rather than passive reporting—can reduce time to detection and help non-experts avoid making decisions based on biased data.Software Engineerin

    Extending a corpus for assessing the credibility of software practitioner blog articles using meta-knowledge

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    Practitioner written grey literature, such as blog articles, has value in software engineering research. Such articles provide insight into practice that is often not visible to research. However, a high quantity and varying quality are two major challenges in utilising such material. Quality is defined as an aggregate of a document's relevance to the consumer and its credibility. Credibility is often assessed through a series of conceptual criteria that are specific to a particular user group. For researchers, previous work has found argumentation' and >evidence' to be two important criteria. In this paper, we extend a previously developed corpus by annotating at broader granularity. We then investigate whether the original annotations (sentence level) can infer these new annotations (article level). Our preliminary results show that sentence-level annotations infer the overall credibility of an article with an F1 score of 91%. These results indicate that the corpus can help future studies in detecting the credibility of practitioner written grey literature

    A critical role for gp96 in lymphopoiesis, thrombopoiesis, and intestinal homeostasis

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    gp96 is an endoplasmic reticulum chaperone for multiple Toll-like receptors and integrins. Our lab has generated a conditional gp96 knockout model allowing gp96 to be efficiently deleted from all tissues. Herein we demonstrate that gp96 is a master chaperone for 14 of 17 hematopoietic specific integrins and the critical role for gp96 in normal B cell and T cell development, but not for myeloid cell development. Additionally, we show that gp96 chaperones the GPIb-IX complex in platelets and is critical for normal platelet development and function, and results in a condition that closely resembles human Bernard-Soulier syndrome. Lastly, we report that global deletion of gp96 in mice results in spontaneous inflammatory bowel-like disease and a surprising role for gp96 in Wnt signaling, which is known to regulate intestinal homeostasis. Thus, my thesis work was aimed at understanding the roles and mechanisms of gp96 in (1) hematopoiesis, (2) platelet development and function, and (3) intestinal homeostasis.

    Rachilde, homme de lettres. Gender and exclusion

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    At a time when the voice of feminists is getting stronger and the number of women writers is increasing, Rachilde’s position seems ambiguous, if not paradoxical. A woman writer herself, an author of several novels appreciated by the public, a literary critic at the Mercure de France, she could become an important figure in the feminist movement. And yet she systematically flouts its claims; she also remains very critical of the women’s writing, of which she refuses to be a part. Hence, it seems interesting to look for the causes of such an attitude. The scope of the subject and, even more, the contradictory statements of Rachilde herself, will at most allow us to formulate some hypotheses. However, we shall examine more closely the problem of Rachilde’s belonging to one or more minorities

    Foreword

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    This multi-author publication collects works of specialists from many scientific fields (including literary studies, cultural studies, sociology, history and more), representing various research centers (from Poland, France, Canada, the Czech Republic, and Saudi Arabia). Although this book’s main purpose isn’t to deal with myths regarding minorities in today’s society, it does provide a deeper understanding of minority-majority relations, based on solid historical and theoretical arguments

    A personal perspective on organisations : head, heart and soul

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    Through a heuristics approach, the author began an exploration of the meaning, both intellectually and emotionally, of personal experiences in organisations. Change and learning was focused on, and how continual rounds of restructuring impacted on the writer as a participant/observer. The lack of spirituality in organisations, how we hide our hearts and souls and how we seek certainty using static models, theories and plans became underlying themes through the work. The findings of the research include outputs such as the development of an organisational model of complexity, but more so outcomes that were the intuitive insights that were gained during the research proces

    Deciphering the Gift of Love: Reading Augustine's De Trinitate through Jean-Luc Marion

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    Degree awarded: Ph.D. Systematic Theology. The Catholic University of AmericaThis dissertation can be viewed by CUA users only.The objective of this dissertation is to develop a new appreciation for how the gift of love traverses the distance between the intended signification of the Trinity and the impossibility--for us--of that very signification.Part I explores the promise of recent scholarship (e.g. that of L. Gioia, M. Hanby, P. Kolbet, L. Ayres) and interprets De Trinitate not as a metaphysical modeling of the Trinity in se, but as an rational study of the limits of theological signification. When read in light of Augustine's understanding of the relationship between hermeneutics and conversion, and emphasizing the missions of the Son and Spirit, De Trinitate offers an exposition of the soteriological transformation of the human person toward remembering, understanding, and loving God.Part II considers the gift of love in the phenomenology of Jean-Luc Marion. Supported by his concept of the saturated phenomenon, Marion offers a rigorous description of the gift of love as advancing according to its own reason and approaching not a conceptual abstraction, but a particular beloved. This gift divests the ego of its self-groundedness, inviting instead a understanding of the subject that is responsive to givenness and love, a subject that is gifted and devoted: the adonné. This rationality of love illuminates the key tension in Marion's work as one between the indetermination and limits of phenomenology and the particularity and excess demanded by the phenomenon of love.Part III is the site of the convergence of Marion's phenomneology with Augustine's own understanding of love's significance to trinitarian revelation. Marion's erotic reduction offers to De Trinitate an iconic description of the love by which God's self-revelation is mediated to us. The responsive love of the adonné sharpens Augustine's concept of the human being as made to the image of God and marks the revelation of the Trinity in the making possible what would otherwise be impossible for us: our advance in love. In turn, De Trinitate provides for Marion the revealed name by which God might be called upon in and through the particularity of love: the Father, Son, and Holy Spirit.Made available in DSpace on 2013-06-25T14:59:15Z (GMT). No. of bitstreams: 1 Staron_cua_0043A_10424display.pdf: 2778321 bytes, checksum: 5d7c6387e313375502cdc90bcb0ca24a (MD5

    Revealing dynamic processes in laser powder bed fusion with in situ X-ray diffraction at PETRA III

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    This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in: Krohmer, E., Schmeiser, F., Wahlmann, B., Rosigkeit, J., Graf, G., Spoerk-Erdely, P., Clemens, H., Staron, P., Körner, C., Reimers, W., & Uhlmann, E. (2022). Revealing dynamic processes in laser powder bed fusion with in situ X-ray diffraction at PETRA III. In Review of Scientific Instruments (Vol. 93, Issue 6, p. 065104). AIP Publishing. https://doi.org/10.1063/5.0077105 and may be found at https://doi.org/10.1063/5.0077105.The high flux combined with the high energy of the monochromatic synchrotron radiation available at modern synchrotron facilities offers vast possibilities for fundamental research on metal processing technologies. Especially in the case of laser powder bed fusion (LPBF), an additive manufacturing technology for the manufacturing of complex-shaped metallic parts, in situ methods are necessary to understand the highly dynamic thermal, mechanical, and metallurgical processes involved in the creation of the parts. At PETRA III, Deutsches Elektronen-Synchrotron, a customized LPBF system featuring all essential functions of an industrial LPBF system, is used for in situ x-ray diffraction research. Three use cases with different experimental setups and research questions are presented to demonstrate research opportunities. First, the influence of substrate pre-heating and a complex scan pattern on the strain and internal stress progression during the manufacturing of Inconel 625 parts is investigated. Second, a study on the nickel-base superalloy CMSX-4 reveals the formation and dissolution of γ′ precipitates depending on the scan pattern in different part locations. Third, phase transitions during melting and solidification of an intermetallic γ-TiAl based alloy are examined, and the advantages of using thin platelet-shaped specimens to resolve the phase components are discussed. The presented cases give an overview of in situ x-ray diffraction experiments at PETRA III for research on the LPBF technology and provide information on specific experimental procedures.DFG, 317078200, In Situ Diffraktion beim Selektiven Laserstrahlschmelze
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