192 research outputs found
L-BAIBA Synergizes with Sub-optimal Mechanical Loading to Promote New Bone Formation
No full textTo investigate potential mechanisms for the synergism of L-BAIBA and mechanical loading on bone formation, RNA Seq was performed on osteocyte-enriched cortical bone from mice treated with L-BAIBA and sub-optimal mechanical loading (8.25N) for either long-term (2 weeks L-BAIBA and loading) or short-term (5 days L-BAIBA and a single bout of mechanical loading). These supplementary data contain the differentially expressed genes and full GO pathway analysis used to create Figures 5-9 in the manuscript. A description for each supplemental file can be found in the 'Supplemental File Legends' document
Drug-releasing nano-engineered titanium implants: therapeutic efficacy in 3D cell culture model, controlled release and stability
No full textAbstract not availableKaran Gulati, Masakazu Kogawa, Matthew Prideaux, David M. Findlay, Gerald J. Atkins, Dusan Losi
Semantic Web Integration of Cultural Heritage Sources
No full textIn this paper, we describe research into the use of ontologies to integrate access to cultural heritage and photographic archives. The use of the CIDOC CRM and CRM Core ontologies are described together with the metadata mapping methodology. A system integrating data from four content providers will be demonstrated
Early response of the human SOST gene to stimulation by 1alpha,25-dihydroxyvitamin D(3)
No full textAvailable online 9 December 2015Abstract not availableAsiri R. Wijenayaka, Matthew Prideaux, Dongqing Yang, Howard A. Morris, David M. Findlay, Paul H. Anderson, Gerald J. Atkin
Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli
No full textAbstract not availableNobuaki Ito, Asiri R. Wijenayaka, Matthew Prideaux, Masakazu Kogawa, Renee T. Ormsby, Andreas Evdokiou, Lynda F. Bonewald, David M. Findlay, Gerald J. Atkin
1alpha,25-dihydroxyvitamin D3 stimulates human SOST gene expression and sclerostin secretion
No full textLink to a related website: http://manuscript.elsevier.com/S0303720715003329/pdf/S0303720715003329.pdf, Open Access via UnpaywallAbstract not availableAsiri R. Wijenayaka, Dongqing Yang, Matthew Prideaux, Nobuaki Ito, Masakazu Kogawa, Paul H. Anderson, Howard A. Morris, Lucian B. Solomon, Gabriela G. Loots, David M. Findlay, Gerald J. Atkin
eCHASE: Sustainable Exploitation of Electronic Cultural Heritage
No full textEurope’s digital cultural heritage content has tremendous exploitation potential in applications such as Education, Publishing, e-Commerce, Public Access and Tourism. Value is hugely amplified if the content can be aggregated, repurposed and distributed at a European level. The eCHASE project seeks to demonstrate that public-private partnerships between content holders and commercial service providers can create new services and a sustainable business based on access and exploitation of digital cultural heritage content. This paper describes these issues and introduces the eCHASE architecture that is being developed to showcase the business models created for the project
eCHASE: Exploiting Cultural Heritage using the Semantic Web
No full textThe eCHASE project is using semantic web technologies to demonstrate sustainable business models based on access and exploitation of digital cultural heritage content at a European level. In this paper we describe the eCHASE project and outline the system architecture
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The ‘Patrick Matthew Effect’ in science
No full textRobert Merton (1968) coined the term “The Matthew Effect in Science” to explain by biblical analogy how famous scientists are sometimes credited more than those who are lesser known but more deserving. Leading Darwin scholars have admitted Patrick Matthew (1831) originated the theory he uniquely called the “natural process of selection”, which Charles Darwin (1859) re-named “process of natural selection”. The current consensus among many Darwin scholars is that Matthew cannot have priority for his theory because he failed to influence anyone. According to Darwin and all Darwin scholars thereafter, neither he nor anyone else read Matthew’s theory before 1859. However, new research has shown, contrary to what has been taught, that Matthew’s book in fact was read and cited by at least 30 scholars before Alfred Wallace’s and Darwin’s replications of 1858 and 1859. These included (i) Robert Chambers (Wallace’s admitted greatest influencer) who met and corresponded with Darwin pre-1858, (ii) John Loudon, an associate of Darwin’s associates, and (iii) Prideaux John Selby, Chief Editor of Wallace’s 1855 Sarawak paper on evolution of species. With a focus on the story of Matthew, Darwin, and Wallace, this chapter addresses the ethics of taking the step to reveal errors of fact in the publication record that have been used to misinform history
Staying on Eat Street Strategies to support community businesses on Nicollet Avenue and Lake Street
No full textCapstone paper for the fulfillment of the Master of Urban and Regional Planning degree.Eat Street is a cultural corridor home to many thriving small businesses owned by immigrants and persons of color. While not all Eat Street restaurant owners are immigrants, the immigrant experience is central to the Eat Street story. “It’s a mixed culture here. It’s not one kind of people. Different position, different cultures, and different people. You have all kinds, all kinds of people” (Eat Street at 20, n.d., Harry Singh, owner of Harry Singh’s Original Caribbean Restaurant). The focus of this semester long research project is to provide targeted strategies that the City of Minneapolis Community Planning and Economic Development (CPED) department can take to support the immigrant and person of color owned businesses along Eat Street as they plan and prepare for projected economic revitalization with the potential reopening of Nicollet Avenue at Lake Street.Strait, Jen; Prideaux, Michael; Goodwin, Matthew; Dressel, Elizabeth. (2018). Staying on Eat Street Strategies to support community businesses on Nicollet Avenue and Lake Street. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/208301
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