43 research outputs found
In Conversation with Steven Schweitzer, Reading Utopia in Chronicles (LHBOTS, 442; London: T. & T. Clark International, 2007)
No full textThis conversation with Steven Schweitzer, Reading Utopia in Chronicles (LHBOTS, 442; London: T. & T. Clark International, 2008) began in a special session of the Chronicles-Ezra-Nehemiah Section of the Society of Biblical Literature held at the SBL annual meeting in November 2007 in San Diego, California. It includes an introduction by the editor and two contributions, one by the editor and Matthew Forrest Lowe and another by Roland Boer, and concludes with a response by Steven Schweitzer.</jats:p
Inflation Targeting: The British Experience
No full textThis lecture describes the United Kingdom's experience with inflation targeting. It provides a historical perspective to the introduction of inflation targeting, discusses the concept of inflation targets, and compares an inflation targeting regime with money supply and exchange rate targeting regimes. It is noteworthy that inflation targeting is based on the assumption that low inflation is the proper objective of monetary policy. A significant portion of the lecture covers the issue of the measurement of inflation. It discusses whether asset prices should be taken into account in the inflation measure and looks in particular at the experience of Japan in the late 1980s. It also considers sources of imperfection in traditional measures. It concludes that monetary policy will have to be conducted by reference to estimated price indexes that fall short of the conceptual ideal but does not regard this as seriously undermining an inflation targeting regime. The lecture goes on to discuss the issues of (1) having a target band for inflation or not, (2) the difficulty in forecasting inflation, and (3) the time horizon over which monetary policy should aim. The lecture highlights the important role that openness and transparency play in achieving credibility in monetary policy. It highlights the five devices that are now in use in the United Kingdom, and notes some of the benefits emerging from the open and transparent nature of the United Kingdom approach. It concludes by warning that inflation targeting does not promise to make monetary policy easy but does have the positive virtue of directing attention to many technical issues that need to be resolved in conducting monetary policy.Inflation, Targeting, British
Review of Eidevall, Göran, Prophecy and Propaganda: Images of Enemies in the Book of Isaiah (Coniectanea Biblica: Old Testament Series, 56; Winona Lake, Ind.: Eisenbrauns, 2009).
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Additional file 1 of Diagnostic delay of myositis: an integrated systematic review
No full textAdditional file 1. Supplementary table 1. Search string conducted on Pubmed/Medline. Supplementary table 2. Data extraction tool. Supplementary table 3. Adapted version of Newcastle-Ottawa score. Supplementary table 4. Data extraction summary of selected studies. Supplementary table 5. Meta-aggregation results of initial symptoms by subtypes of IIM. Factors identified in case studies as related to diagnostic delay. Supplementary table 6. Factors identified in case studies as related to diagnostic delay. Supplementary table 7. Factors of diagnostic delay by myositis types. Supplementary figure 1. Adapted version of Newcastle-Ottawa score. Supplementary figure 2. Contour-Enhanced funnel plot for mean diagnostic delay in diagnosis (n = 19). Supplementary figure 3. Forrest plot for mean diagnostic delay in all studies reporting standard deviation (no = SD not estimated, yes = SD estimated). Supplementary figure 4. Forrest plot for mean diagnostic delay in MSA tested and not tested studies. Supplementary figure 5. forrest plot for mean diagnostic delay in Peter Bohan's criteria and ENMC criteria. Supplementary figure 6. Forrest plot for mean diagnostic delay in multidisciplinary and specialist centres. Review protocol: Diagnostic delay of myositis: a protocol of an integrated systematic review
ALT-C 2011 Abstracts
No full textThis is a PDF of the abstracts for all the sessions at the 2011 ALT conference. It is designed to be used alongside the online version of the conference programme. It was made public on 1 September, with a "topped and tailed" made live on 2 September
Renaissance humanism and John Merbecke's - The booke of Common praier noted (1550)
No full textRenaissance humanism was an intellectual technique which contributed most to the origin and development of the Reformation. While the relation of Renaissance humanism and the Reformation is of considerable interest in the realms of history and theology, it has seldom been examined from a musicological perspective. This study aims to fill that gap by elucidating the way humanist musical thought influenced Reformation attitudes to music, with particular reference to the sixteenth-century reform of plainchant. The focus of the study is on the musical manifestation of the English Reformation, The booke of Common praier noted (BCPN, 1550) by John Merbecke (c.1505 - C.1585). Drawing upon issues of the interpretation of Renaissance humanism and its relation to the Reformation, the thesis challenges existing understandings of Merbecke and his music. Chapter one is a biographical study to re-appraise Merbecke's careers and outlooks in the light of Renaissance humanism, especially of Erasmian lines. It serves as a starting point for re-evaluating the significance of BCPN in relation to humanist musical thought. Chapter two explores the musical framework of Erasmian humanism which became a major intellectual basis for the renewal of Christian music on the eve of the Reformation. Chapter three reveals the core of Anglican plainchant apologetics underlying BCPN, illustrating that the musico- rhetorical and ethical associations of humanism played an integral part in shaping the Anglican criteria of true ecclesiastical music. Chapter four argues that two humanist conceptions were integrated into the programme of the reform of plainchant in BCPN: 'rhetorical theology' (theologia rhetorica) and 'rhetorical music' (musica rhetorica). It explores word-tone relations in BCPN, thereby demonstrating its characteristics as a humanist plainchant directed towards the 'rhetoricisation of music'; it sheds a new light upon Merbecke's notation and modes in BCPN, especially in relation to the ‘theory of accented singing' and the doctrine of 'mode ethos’
Novel cell models for the study of spinocerebellar ataxia type 7 pathogenesis and therapy in a South African patient cohort
No full textIncludes abstract.Includes bibliographical references.Spinocerebellar ataxia type 7 (SCA7) is a dominantly-inherited neurodegenerative disease, resulting from a CAG trinucleotide repeat expansion in the ataxin-7 gene. The Ataxin-7 protein is known to play a role in transcriptional regulation through association with cellular histone acetylation complexes, and several studies have highlighted the role of transcriptional dysregulation, caused by the presence of mutant Ataxin-7, in the neuronal dysfunction that precedes the onset of disease symptoms.This study aimed to establish patient-derived cell models of SCA7, for use in the investigation of pathogenesis (with particular reference to transcriptional alterations), and in the evaluation of previously-developed therapies for the disease.The high prevalence of SCA7 in the South African population, as a result of a founder effect, makes this disease particularly amenable to allele-specific RNA interference (RNAi)-based therapy. Thus, this study also evaluated the feasibility of these cell models as a vehicle to test previously-developed RNAi therapeutics, using the alteration of expression of key transcripts as a phenotypic marker. SCA7 patient and control dermal fibroblasts were reprogrammed to pluripotency by retroviral transduction. The resultant induced pluripotent stem cell (iPSC) lines were characterised with respect to endogenous markers of pluripotency, differentiation capacity and transgene silencing. These cells were then subjected to neuronal differentiation, the success of which was confirmed by the expression of early neuronal markers
