4,395 research outputs found

    Zechariah and the Gospel off Matthew: the use of a biblical tradition

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    This thesis examines the use of Zechariah traditions in Matthew's Gospel. It analyzes and interprets the ways Matthew transmits, alters or adds Zechariah traditions to his sources. Instead of looking at portions of the Gospel in light of Zechariah 9-14 only, this study addresses the entire Gospel and all of Zechariah. In focusing on Zechariah tradition, the thesis has kept the following considerations in view. First, the content and function of Matthew's explicit uses of Zechariah are examined. Second, ways in which tradition derived from Zechariah may have exerted influence on portions of the gospel sub-structure are identified. Third, it explores the extent to which Matthew alludes to characteristic Zechariah themes. Together, these components illuminate how Matthew's Gospel incorporates its Zechariah material, whether alone or in combination with other prophetic traditions. Thus the methodological approach of the thesis is not only grounded in classical methods of biblical criticism but is also open to recent literary methods. In addition to explicit citations, numerous allusions and echoes of Zechariah tradition are present in Matthew. They appear in Matthean materials and in traditions Matthew has taken from Mark and Q. Because the focus of this thesis is open to both the Gospel and the Zechariah traditions in their entirety, two important observations have been made. First, traces of Zechariah material are found in the Infancy and Gaililean healing Narratives as well as in the Passion Narrative. Not only is the impact of Zechariah 9-14 observed, but important sections of Zechariah 1-8 are also discerned in Matthew's narrative structure. Moreover, Matthew's Son of David Christology is enriched and partially defined by Zechariah's prophet-shepherd imagery, as well as by the royal messianic motif

    Wisdom and apocalyptic in the Gospel of Matthew : a comparative study with 1 Enoch and 4QInstruction

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    Recent scholarship has demonstrated that Matthew's gospel has significantly developed both sapiential and apocalyptic elements within its narrative. Little attention has been paid, however, to the question of how these two features of Matthew's gospel might relate to one another. It is this gap in scholarly literature that the present study is intended to fill, by means of a comparative study with two other texts of mixed genre: 1 Enoch and 4Qlnstruction. An examination of these texts demonstrates that each is marked by an inaugurated eschatology, within which the revealing of wisdom to an elect group, defined in distinction to the Jewish parent group, serves as the pivotal moment of inauguration. In addition, within 4Qlnstruction the idea is developed that possession of this revealed wisdom allows the remnant to live in fidelity to the will of the Creator and to the patterns built-in to the original creation. Thus, possession of revealed wisdom facilitates a recovery of creation. These findings provide lines of enquiry that may be brought to Matthew. Three sections of the gospel are examined (chapters 5-7; 11-12; 24-25). It is argued that Jesus is presented as an eschatological figure who reveals wisdom to an elect group. This wisdom cannot be reduced to great moral insight or interpretation of Torah, but is presented as prophetic revelation, happening in eschatological time. It remains the case, however, that Matthew presents it as wisdom and presents Jesus as a sage. More tentatively, it is suggested that creation provides the patterns for the ethical requirements of Jesus' wisdom, thus indicating that the idea of restored creation is also at work in Matthew. The fall of the temple may also be connected in Matthew's narrative to such a restoration, but again, the evidence for this is not clear

    Estimating Total Energy Expenditure to Determine Energy Requirements in Free-Living Children With Stage 3 Chronic Kidney Disease: Can a Structured Approach Help Improve Clinical Care?

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    Objective: malnutrition and obesity are complex burdensome challenges in pediatric chronic kidney disease (CKD) management that can adversely affect growth, disease progression, wellbeing, and response to treatment. Total energy expenditure (TEE) and energy requirements in children are essential for growth outcomes but are poorly defined, leaving clinical practice varied and insecure. The aims of this study were to explore a practical approach to guide prescribed nutritional interventions, using measurements of TEE, physical activity energy expenditure (PAEE), and their relationship to kidney function.Design and Methods: in a cross-sectional prospective age-matched and sex-matched controlled study, 18 children with CKD (6-17 years, mean stage 3) and 20 healthy, age-matched, and gender-matched controls were studied. TEE and PAEE were measured using basal metabolic rate (BMR), activity diaries and doubly labeled water (healthy subjects). Results were related to estimated glomerular filtration rate (eGFR). The main outcome measure was TEE measured by different methods (factorial, doubly labeled water, and a novel device).Results: total energy expenditure and PAEE with or without adjustments for age, gender, weight, and height did not differ between the groups and was not related to eGFR. TEE ranged from 1927 ± 91 to 2330 ± 73 kcal/d; 95 ± 5 to 109 ± 5% estimated average requirement (EAR), physical activity level (PAL) 1.52 ± 0.01 to 1.71 ± 0.17, and PAEE 24 to 34% EAR. Comparisons between DLW and alternative methods in healthy children did not differ significantly, except for 2 (factorial methods and a fixed PAL; and the novel device).Conclusion: in clinical practice, structured approaches using supportive evidence (weight, height, BMI sds), predictive BMR or TEE values and simple questions on activity, are sufficient for most children with CKD as a starting energy prescription

    Gilbert Hottois y la “Species Technica”

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    Purpose/Context. The purpose of this article is to provide a new light on the work of Gilbert Hottois and unpublished documents from his autobiography to analyze the evolution of the author\u27s thought. Methodology/Approach. The methodology used is qualitative. It is based on the study of Hottois\u27 work and his notes for an autobiographical project, in which he outlined a brief chronology of the evolution of his topics of interest. Results/Findings. The evolution of author Gilbert Hottois\u27 thought was identified in light of: (i) his interest in science fiction in the 1950s and 1960s, (ii) the publication of his doctoral thesis and his first books on philosophy between 1970 and 1980, (iii) the appearance in 1981 of his novel "Species Technica", (iv) the publication in 1984 of the book "Le Signe et la Technique", (v) his reflections on bioethics between 1985 until the early 2000s, and (vi) his later contributions on science fiction and transhumanism. Discussion/Conclusions/Contributions. The philosophy of technoscience and the question of the future of man are primary elements in understanding the thought of Gilbert Hottois. His work should be seen around the theme of the long-term transformation of mankind through technoscience and thus Hottois should be recognized for his contributions to the reflection and study on the mutation of man due to technology.Propósito/Contexto. El objetivo de este artículo es dar una nueva mirada a la obra de Gilbert Hottois y a documentos inéditos de su autobiografía, para analizar la evolución del pensamiento del autor. Metodología/Enfoque. La metodología utilizada es cualitativa, basada en el estudio de la obra de Hottois y en sus notas para un proyecto autobiográfico, en las cuales esbozó una breve cronología de la evolución de sus temas de interés. Resultados/Hallazgos. Se identificó la evolución del pensamiento del autor Gilbert Hottois a la luz de: (i) su interés en la ciencia ficción en las décadas de 1950 y 1960, (ii) la publicación de su tesis doctoral y sus primeros libros de filosofía entre 1970 y 1980, (iii) la aparición en 1981 de su novela “Species Technica”, (iv) la publicación en 1984 del libro “Le Signe et la Technique”, (v) sus reflexiones sobre bioética entre 1985 hasta principios de la década de 2000, y (vi) sus posteriores contribuciones sobre la ciencia ficción y el transhumanismo. Discusión/Conclusiones/Contribuciones. La filosofía de la tecnociencia y la cuestión del futuro del hombre son elementos primordiales para comprender el pensamiento de Gilbert Hottois. Su obra debe ser vista en torno al tema de la transformación a largo plazo de la humanidad a través de la tecnociencia y por ende Hottois debe ser reconocido por sus contribuciones a la reflexión y estudio sobre la mutación del hombre debido a la tecnología.Objetivo/Contexto. O objetivo deste artigo é dar um novo olhar ao trabalho de Gilbert Hottois e a documentos inéditos de sua autobiografia, a fim de analisar a evolução do pensamento do autor. Metodologia/Aproximação. A metodologia utilizada é qualitativa, baseada no estudo do trabalho de Hottois e suas notas para um projeto autobiográfico, no qual ele esboçou uma breve cronologia da evolução de seus temas de interesse. Resultados/Descobertas. A evolução do pensamento do autor Gilbert Hottois foi identificada à luz do (i) seu interesse pela ficção científica nos anos 50 e 60, (ii) a publicação de sua tese de doutorado e seus primeiros livros sobre filosofia entre 1970 e 1980, (iii) o aparecimento em 1981 de seu romance "Species Technica", (iv) a publicação em 1984 do livro "Le Signe et la Technique", (v) suas reflexões sobre bioética entre 1985 e o início dos anos 2000, e (vi) suas contribuições posteriores sobre ficção científica e transhumanismo. Discussão/Conclusões/Contribuições. A filosofia da tecnociência e a questão do futuro do homem são elementos primários na compreensão do pensamento de Gilbert Hottois. Seu trabalho deve ser visto em torno do tema da transformação a longo prazo da humanidade através da tecnociência e, portanto, Hottois deve ser reconhecido por suas contribuições para a reflexão e estudo da mutação do homem devido à tecnologia

    Service-oriented grids and problem solving environments

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    The Internet’s continued rapid growth is creating an untapped environment containing a large quantity of highly competent computing resources suitable for exploitation in existing capacity-constrained and new innovative capability-driven distributed applications. The Grid is a new computing model that has emerged to harness these resources in a manner that fits the problem solving process needs of the computational engineering design community. Their unique requirements have created specific challenges for Grid technologies to bring interoperability, stability, scalability and flexibility, in addition to, transparent integration and generic access to disparate computing resources within and across institutional boundaries.The emergence of maturing open standards based service-oriented (SO) technologies has fulfilled the fundamental requirements of interoperability, leaves a flexible framework onto which sophisticated system architectures may be built, and provides a suitable base for the development of future Grid technologies. The work presented in this thesis is motivated by the desire to identify, understand, and resolve important challenges involved in the construction of Grid-enabled Problem Solving Environments (PSE) using SO technologies. The work explains why they are appropriate for Grid computing and successfully demonstrates the application and benefits of applying SO technologies in the scenarios of Computational Micromagnetics and Grid-enabled Engineering Optimisation and Design Search (Geodise) systems. Experiences achieved through the work can also be of referential value to future application of Grid computing in different areas

    Gilbert Hottois y la “Species Technica”

    No full text
    Purpose/Context. The purpose of this article is to provide a new light on the work of Gilbert Hottois and unpublished documents from his autobiography to analyze the evolution of the author's thought. Methodology/Approach. The methodology used is qualitative. It is based on the study of Hottois' work and his notes for an autobiographical project, in which he outlined a brief chronology of the evolution of his topics of interest. Results/Findings. The evolution of author Gilbert Hottois' thought was identified in light of: (i) his interest in science fiction in the 1950s and 1960s, (ii) the publication of his doctoral thesis and his first books on philosophy between 1970 and 1980, (iii) the appearance in 1981 of his novel "Species Technica", (iv) the publication in 1984 of the book "Le Signe et la Technique", (v) his reflections on bioethics between 1985 until the early 2000s, and (vi) his later contributions on science fiction and transhumanism. Discussion/Conclusions/Contributions. The philosophy of technoscience and the question of the future of man are primary elements in understanding the thought of Gilbert Hottois. His work should be seen around the theme of the long-term transformation of mankind through technoscience and thus Hottois should be recognized for his contributions to the reflection and study on the mutation of man due to technology.Propósito/Contexto. El objetivo de este artículo es dar una nueva mirada a la obra de Gilbert Hottois y a documentos inéditos de su autobiografía, para analizar la evolución del pensamiento del autor. Metodología/Enfoque. La metodología utilizada es cualitativa, basada en el estudio de la obra de Hottois y en sus notas para un proyecto autobiográfico, en las cuales esbozó una breve cronología de la evolución de sus temas de interés. Resultados/Hallazgos. Se identificó la evolución del pensamiento del autor Gilbert Hottois a la luz de: (i) su interés en la ciencia ficción en las décadas de 1950 y 1960, (ii) la publicación de su tesis doctoral y sus primeros libros de filosofía entre 1970 y 1980, (iii) la aparición en 1981 de su novela “Species Technica”, (iv) la publicación en 1984 del libro “Le Signe et la Technique”, (v) sus reflexiones sobre bioética entre 1985 hasta principios de la década de 2000, y (vi) sus posteriores contribuciones sobre la ciencia ficción y el transhumanismo. Discusión/Conclusiones/Contribuciones. La filosofía de la tecnociencia y la cuestión del futuro del hombre son elementos primordiales para comprender el pensamiento de Gilbert Hottois. Su obra debe ser vista en torno al tema de la transformación a largo plazo de la humanidad a través de la tecnociencia y por ende Hottois debe ser reconocido por sus contribuciones a la reflexión y estudio sobre la mutación del hombre debido a la tecnología.Objetivo/Contexto. O objetivo deste artigo é dar um novo olhar ao trabalho de Gilbert Hottois e a documentos inéditos de sua autobiografia, a fim de analisar a evolução do pensamento do autor. Metodologia/Aproximação. A metodologia utilizada é qualitativa, baseada no estudo do trabalho de Hottois e suas notas para um projeto autobiográfico, no qual ele esboçou uma breve cronologia da evolução de seus temas de interesse. Resultados/Descobertas. A evolução do pensamento do autor Gilbert Hottois foi identificada à luz do (i) seu interesse pela ficção científica nos anos 50 e 60, (ii) a publicação de sua tese de doutorado e seus primeiros livros sobre filosofia entre 1970 e 1980, (iii) o aparecimento em 1981 de seu romance "Species Technica", (iv) a publicação em 1984 do livro "Le Signe et la Technique", (v) suas reflexões sobre bioética entre 1985 e o início dos anos 2000, e (vi) suas contribuições posteriores sobre ficção científica e transhumanismo. Discussão/Conclusões/Contribuições. A filosofia da tecnociência e a questão do futuro do homem são elementos primários na compreensão do pensamento de Gilbert Hottois. Seu trabalho deve ser visto em torno do tema da transformação a longo prazo da humanidade através da tecnociência e, portanto, Hottois deve ser reconhecido por suas contribuições para a reflexão e estudo da mutação do homem devido à tecnologia

    Nutritional Characterisation of Childhood Chronic Kidney Disease: Trace Element Malnutrition in Paediatric Renal Disease (TeMPeReD) Study

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    Background/Objectives: In chronic kidney disease (CKD), poor nutrition is associated with poorer clinical outcomes. There are limited data on milder stages of childhood CKD. Methods: This study characterised the nutritional state of a cohort of children with CKD. Results: Within the cohort (mean age 10.5 years, mean eGFR = 57 mL/min/1.73 m2), obesity defined by body mass index rates was comparable to that in the general population, but central obesity (waist-to-height ratio > 0.5) was evident in 44% of children. Although average nutrient intakes for the cohort were acceptable, there was marked variability in the risk of poor nutrient intake (<LRNI): selenium (35%), magnesium (35%), iodine (30%), and zinc (30%). No child met the recommended dietary fibre intake. The prevalence of frank deficiency of vitamins and minerals in blood concentrations was low. Blood concentrations of vitamins A and E were near-universally elevated. In those who had a decline in kidney function at the 12-month follow-up, dietary intake of fibre correlated with the degree of decline. Conclusions: Much work is needed to optimise the nutritional status of children with CKD as an important modifiable risk factor for disease progression and other important outcomes

    Boulton and Fothergill silver.

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    PhDThis thesis is about the silver business of Matthew Boulton and John Fothergill at their Soho Manufactory near Birmingham. Their partnership lasted from 1762 until 1782. A rounded discussion of the topic is attempted. Within the contexts of industry elsewhere and Soho's other activities, successive chapters cover the early development, marketing, production, design, and later decline of the partners' silver. Silver plate was prestigious and, untypically for Boulton, he concentrated on sales to the public rather than trade customers. To attract orders he made modest charges. This was viable where mainly machinery was used to make plate, even though sales were not high, since the expense of machinery was substantially covered by the larger sales of non-silver items. However, where Boulton relied to a greater degree upon hand methods, he lacked technical means to compensate for low profit-margins. Moreover, inefficiency and the firm's lack of capital which led to substantial bankers' interest charges on payment for bullion, particularly when customers paid late, caused losses. These problems applied particularly to silver plate and were mainly responsible for the decision to reduce production drastically; however, the manufacture of a large range of small items remained relatively consistent. The thesis includes appendices. Some contain new information about annual totals for the following aspects of the business: the volume of assay silver; each type of article; pieces sold on commission; and sterling silver supplies. Other appendices provide details about the partners' silversmiths and extracts from a Soho inventory. This thesis involves a more detailed use of sources than previous studies of the topic. Apart from the silver itself (which is selectively illustrated), the Matthew Boulton Papers and statistics derived from The Birmingham Assay office provide the main sources. Manuscripts covering silver production elsewhere provide contextual material for understanding the partners' silver business

    Vitamin B6 in pediatric renal transplant recipients

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    Objectives: Our aim was to assess the vitamin B6 intake and biochemical status in a sample of children who have undergone renal transplantation. Methods: A prospective observational study was performed in 10 pediatric renal transplant recipients to determine their vitamin B6 status through dietary assessment and serum Pyridoxal 5′-phosphate (PLP) measurement. Results: Ten children (mean age of 11.9 years) had median serum PLP concentrations of 62.45 nmol/L (interquartile range ±83.40). Two children (20%) had values above the reference range, and none below. Mean vitamin B6 intake was 138.7% of reference nutrient intake (standard deviation ±35.2%). No children were in receipt of vitamin B6 supplementation. Conclusion: There is no previous literature on vitamin B6 status in children who have undergone renal transplantation. In adult transplant recipients, elevated serum PLP concentrations have been described and ascribed to possible excessive intakes. In this sample, no children appeared biochemically deficient, but 20% had elevated concentrations. Dietary intakes were not excessive, and no children reported oral Vitamin B6 supplementation. Exploration of vitamin B6 metabolism in this population is required.</p

    Association of nutritional status and health-related quality of life in children with chronic kidney disease

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    Purpose: Health-related quality of life (HRQoL) is an important, patient-centred measure. Although nutritional status is altered in children with CKD, the impact of nutritional status on HRQoL in this population has not been explored. The aims of this study are to report the HRQoL scores as assessed by the validated PedsQL™ questionnaire and to explore the relationship of HRQoL scores to markers of nutritional status. It will also examine the concordance between the scores of the child and their parent/carer. Methods: A single-centre, cross-sectional, observational study was performed exploring the markers of nutritional status (anthropometry—including presence of obesity, micronutrient status and appetite) and HRQoL and assessed by the PedsQL™ questionnaire in children aged 3–18 years with pre-dialysis, conservatively managed CKD. Results: A total of 46 children were recruited, with a mean age of 10.5 years. HRQoL scores were lower than in healthy controls throughout all domains. Lower scores were associated with short stature and poor appetite. Markers of obesity or micronutrient status were not associated with HRQoL scores. Discussion: Nutritional status impacts upon HRQoL. Further study is needed to evaluate how changing nutritional status may affect HRQoL in children with CKD, and this may be used to facilitate the development of patient-centred treatment goals and plans.</p
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