84 research outputs found
“Ooh Aah…, Just a Little Bit”: a small amount of side channel can go a long way
No full textLecture Notes in Computer Science, vol. 8731We apply the FLUSH+RELOAD side-channel attack based on cache hits/misses to extract a small amount of data from OpenSSL ECDSA signature requests. We then apply a “standard” lattice technique to extract the private key, but unlike previous attacks we are able to make use of the side-channel information from almost all of the observed executions. This means we obtain private key recovery by observing a relatively small number of executions, and by expending a relatively small amount of post-processing via lattice reduction. We demonstrate our analysis via experiments using the curve secp256k1 used in the Bitcoin protocol. In particular we show that with as little as 200 signatures we are able to achieve a reasonable level of success in recovering the secret key for a 256-bit curve. This is significantly better than prior methods of applying lattice reduction techniques to similar side channel information.Naomi Benger, Joop van de Pol, Nigel P. Smart, and Yuval Yaro
Climate change policy in Canada: domestic influences on foreign policy formulation
No full textThis thesis examines the domestic politics that infuence government decison making. Specifically, how these domestic constituents, such as institutions, organizations and individuals, shape how the Canadian government formulates and impliments environmental policy. It will do so by providing a comparative analysis using the Chretien and Harper governments.October 201
Prehospital intubation in cardiac arrest: The debate continues
No full textNo abstract: this is an editoria
Pre-hospital resuscitation using the iGEL
No full textWe report our findings on the use of the iGEL (Intersurgical: Wokingham, UK) as an airway device during pre-hospital resuscitation
Autism spectrum disorder: prospects for treatment using gene therapy
No full textAutism spectrum disorder (ASD) is characterised by the concomitant occurrence of impaired social interaction; restricted, perseverative and stereotypical behaviour; and abnormal communication skills. Recent epidemiological studies have reported a dramatic increase in the prevalence of ASD with as many as 1 in every 59 children being diagnosed with ASD. The fact that ASD appears to be principally genetically driven, and may be reversible postnatally, has raised the exciting possibility of using gene therapy as a disease-modifying treatment. Such therapies have already started to seriously impact on human disease and particularly monogenic disorders (e.g. metachromatic leukodystrophy, SMA type 1). In regard to ASD, technical advances in both our capacity to model the disorder in animals and also our ability to deliver genes to the central nervous system (CNS) have led to the first preclinical studies in monogenic ASD, involving both gene replacement and silencing. Furthermore, our increasing awareness and understanding of common dysregulated pathways in ASD have broadened gene therapy’s potential scope to include various polygenic ASDs. As this review highlights, despite a number of outstanding challenges, gene therapy has excellent potential to address cognitive dysfunction in ASD
The 'true use of reading' : Sarah Fielding and mid eighteenth-century literary strategies.
No full textPhDThe aim of this thesis is to explore, by examining her life and
works, how Sarah Fielding (1710-68) established her identity as an author.
The definition of her role involves her notions of the functions of
writing and reading.
Sarah Fielding attempts to invite readers to form a sense of ties
by tacit understanding of her messages. As she believes that a work
of literature is produced through collaboration between the writer and
the reader, it is an important task in her view to show her attentiveness
toward reading practice. In her consideration of reading, she has two
distinct, even opposite views of her audience: on the one hand a familiar
and limited circle of readers with shared moral and cultural values and
on the other potential readers among the unknown mass of people. The
dual targets direct her to devise various strategies. She tries to
appeal to those who can endorse and appreciate her moral values as well
as her learning. Her writings and letters testify that she is sensitive
to the demands of the literary market, trying to lead the taste of readers
by inventing new forms.
The thesis opens with an overview of Sarah Fielding's career,
followed by a consideration of her critical attention to the roles of
reading. I go on to examine the narrative structures and strategies
she deploys, with a particular emphasis on her use of the epistolary
method. The following chapter deals with her attention to the reading
of the moral message tangibly embodied in her educational writing. It
is followed by an analysis of the activity which earned her a reputation
as a learned woman. Various as the forms of her works are, they invariably
reflect her attempt to balance herself between the two demands of
inventiveness and familiarity
Comparing APLS and oranges:caution with the use of direct-acting oral anticoagulants (DOACs) instead of warfarin in the treatment of antiphospholipid syndrome (APLS)
No full textA 63-year-old woman with known antiphospholipid syndrome (APLS) presented with catastrophic APLS and multiorgan dysfunction after a change in her anticoagulation from warfarin to rivaroxaban. Evidence suggests direct-acting oral anticoagulants (DOACs) like rivaroxaban may be less effective than warfarin in secondary prevention of thrombotic events in high-risk APLS patients.</p
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