196 research outputs found
Influence of rotation on axisymmetric plasma equilibria: double-null DTT scenario
Get PDFWe study the dependence of some relevant tokamak equilibrium quantities on
the toroidal plasma rotation. The Grad-Shafranov equation generalised to the
rotating case is analytically solved employing two different representations
for the homogenous solution. Using an expression in terms of polynomials, we
describe the separatrix shape by a few geometrical parameters, reproducing
different plasma scenarios such as double-null and inverse triangularity. In
this setting, the introduction of toroidal rotation corresponds to variations
on relevant plasma quantities, most notably an enhancement of the poloidal
beta. Using a more general expression in terms of Bessel functions, we
reconstruct the full plasma boundary of the double-null configuration proposed
for the upcoming DTT experiment, demonstrating how said configuration is
compatible with different values of the plasma velocity.Comment: 7 pages, 6 figures. Submitted to PPC
The use of FEA packages in the simulation of a drawing operation with springback, in the presence of random uncertainty
No full textThe springback response on a stamped part, calculated by finite element analysis has been evaluated taking into account the uncertainty of some process conditions. In fact, in the simulation of sheet metal forming and springback, a traditional deterministic approach is not able to take into account the uncertain physical variations related to material characteristics, friction conditions, tools active surfaces status, etc.
During sheet metal forming operations many different sources of non-controllable process variations usually display their effect leading to a degree of uncertainty in the final parts’ quality. For this reason, statistical tools and methods are increasingly being used in combination with FE numerical simulation. Then, if one of the purposes of process design is to study and model robustness or reliability of a given process in aleatory conditions, a CAE study might become a feasible way to do it.
Today, the evaluation of the performances of a sheet metal stamping process, under uncertainty of the main variables, is possible using several commercial FEA packages. These software tools automatically allow the pre-emptive evaluation of the robustness of technological decisions and the process sensitivity to a random variation of uncontrollable parameters or conditions. For accurate calculations these innovative numerical approaches usually require a considerable amount of computational work both in terms of CPU time and in terms of number of CPUs. A specific experimental and numerical activity has been developed in order to better understand the technical capabilities in terms of process simulation in stochastic conditions
Diffusive time evolution of the Grad-Shafranov Equation for a Toroidal Plasma
Get PDFWe describe the evolution of a plasma equilibrium having a toroidal topology
in the presence of constant electric resistivity. After outlining the main
analytical properties of the solution, we illustrate its physical implications
by reproducing the essential features of a scenario for the upcoming Italian
experiment Divertor Tokamak Test Facility, with a good degree of accuracy.
Although we find the resistive diffusion timescale to be of the order of
s, we observe a macroscopic change in the plasma volume on a timescale
of s, comparable to the foreseen duration of the plasma discharge by
design. In the final part of the work, we compare our self-consistent solution
to the more common Solov'ev one, and to a family of nonlinear configurations.Comment: 15 pages, 2 figure
Imsejhin ghall-qadi tal-komunita` Nisranija permezz tal-ministeru sacerdotali
Get PDFThe article focuses upon the call to service through the exercise of the priestly ministry. The point of departure of the study is the Johannine pericope which describes the washing of the disciples' feet by Jesus (Jn 13:1-20). The article describes how the celebration of the liturgy is a fount of vocations to the ordained ministry. The author then studies three documents of the Second Vatican Council -- Optatam Totius, Presbyterorum Ordinis and Christus Dominus -- in order to depict the centrality of service to priestly ministry. A number of evocative texts are referred to, as well as formation documents from the local Church of Malta. Furthermore, the respective contributions of Bishop Tonino Bello, Pope Benedict XVI and Pope Francis are also given pride of place, as more light is thrown on the theme of the article.peer-reviewe
Trattamento del carcinoma del pancreas. Attualità e prospettive
No full textPancreatic ductal adenocarcinoma (PDAC) is still one of the deadliest solid malignancies, with an extremely poor prognosis, with a 1-year survival rate of approximately 20%. Low survival rates of PDAC mainly derive from late diagnosis, with only a minority of patients amenable to surgery, as well as high rates of relapse and lack of effective treatments for advanced disease stages. As a result, there is an urgent need for the development of new effective therapies. At present, the greatest step towards an improvement of treatment has been made with the introduction of two combination chemotherapy regimens, namely FOLFIRINOX (folinic acid, 5-fluorouracil, irinotecan and oxaliplatin) and gemcitabine/nab-paclitaxel. However, current research is also taking a multidirectional approach aiming at developing new treatment options, such as the use of agents targeting the oncogenic network signaling of KRAS or the extracellular matrix, as well as immune therapies
Selected news from the 2014 Genitourinary Cancers Symposium: translating novel strategies into clinical practice
No full text2014 Genitourinary Cancers Symposium San Francisco, CA, USA, 30 January-1 February 2014 The American Society of Clinical Oncology symposium dedicated to genitourinary tumors represents an unmissable opportunity for the whole oncology community with a special interest in the diagnosis and treatment of genitorurinary tract malignancies, in particular kidney and prostate tumors. The 2014 Genitourinary Cancers Symposium focused attention on the need to find a personalized therapy for metastatic renal cell carcinoma and castration-resistant prostate cancer patients. The development of biomarkers for tumor response and/or resistance will represent a major step in this context and has been the focus of several researches at the symposium
Wolff, Spinoza, and the Interpretation of Scripture
No full textDespite his long-standing opposition to Spinoza, Christian Wolff was depicted by many as a crypto-Spinozist himself. Scholars have so far focused mainly on Wolff’s metaphysical doctrines in order to settle the issue of his alleged commitment to Spinozism. However, there is evidence that Wolff had already been suspected of Spinozism long before the 1720s, at the very beginning of his career, and not because of his metaphysics but because of his exegetical method and his defense of Copernicanism against the received interpretation of Josh. 10:12-13. This chapter offers a reconstruction of that episode and explores the hypothesis that remnants of Spinoza’s Tractatus Theologico-Politicus are present in Wolff’s early hermeneutics and especially in his reformulation of the so-called accommodation doctrine. The possibility that Wolff’s first contact with Spinoza did not concern the metaphysics of the Ethica but the exegetical principles of the TTP opens up a new perspective on Wolff’s complex relation to Spinozism
A comparative analysis of opioid-free and opioid-sparing anaesthesia techniques for laparoscopic ovariectomy in healthy dogs
No full textOpioids are widely used for perioperative analgesia in both human and veterinary anaesthesia. Intravenous (IV) opioids are administered to blunt the sympathetic response, often used as a pain surrogate during surgery (Pascoe 2000). Similarly, throughout the postoperative period, opioids are used to veterinarians may not have access to these analgesic drugs and may struggle to find reasonable options to manage pai
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