1,720,976 research outputs found
Diagnostic utility of power Doppler sonography in superficial non-metastatic lymphadenopathy
No full text
Reproducibility and repeatability of foveal avascular zone area measurements using swept-source optical coherence tomography angiography in healthy subjects
No full textPURPOSE:
To assess the reproducibility and repeatability of foveal avascular zone (FAZ) area measurements using swept-source optical coherence tomography angiography (SS-OCTA) in healthy subjects.
METHODS:
Sixty-four eyes of 64 healthy volunteers were randomly subjected to FAZ area measurements using SS-OCTA by 2 examiners in 2 different sessions.
RESULTS:
The FAZ areas measured by the first and second observer were 0.269 ± 0.092 mm2 and 0.270 ± 0.090 mm2, respectively. Within subjects, the coefficients of variations were 2.44% (95% confidence interval [CI] 1.95% to 2.93%) and 2.66% (95% CI 2.00% to 3.31%) for the first and second observers, respectively. The coefficient of repeatability average measurements of FAZ area were 0.021 mm2 and 0.024 mm2. The intraclass correlation coefficient values were 0.993 (95% CI 0.989 to 0.996) and 0.991 (95% CI 0.986 to 0.995). Interobserver and intraobserver concordance correlation coefficients ranged from 0.998 (95% CI 0.997 to 0.999) to 0.999 (95% CI 0.998 to 0.999) and from 0.989 (95% CI 0.982 to 0.993) to 0.987 (95% CI 0.979 to 0.992), respectively.
CONCLUSIONS:
The FAZ area measurements by means of SS-OCTA showed high reproducibility and repeatability in healthy eyes
Diagnostic utility of an echo-contrast agent in patients with synovitis using power Doppler ultrasound: a preliminary study with comparison to contrast-enhanced MRI
No full textSuperficial inflammatory and primary neoplastic lymphadenopathy: diagnostic accuracy of power-doppler sonography.
No full textMicrovascular changes after vitrectomy with internal limiting membrane peeling: an optical coherence tomography angiography study
No full textPURPOSE: To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM).
METHODS:
A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolled in the study. Patients were treated with pars plana vitrectomy followed by ERM and ILM peeling. Subjects were evaluated at baseline and at the week-1 and month-1 follow-up visits. At each visit, patients were evaluated with a complete ophthalmologic evaluation, which included imaging with optical coherence tomography angiography.
RESULTS:
Overall, the SCP vessel density was 43.0 ± 3.0% at baseline and was stable throughout the follow-up (40.0 ± 4.0% at week-1 and 41.0 ± 4.0% at month-1 follow-up visits; p = 0.087 and p = 0.426, respectively). Nevertheless, the SCP vessel density was reduced at week-1 visit in both the superior and inferior sectors. In these sectors, the superficial vessel density was still reduced at the month-1 follow-up visit.
CONCLUSIONS:
We observed a reduction in the SCP vessel density occurring after pars plana vitrectomy with ILM peeling. The reduction is referred to those areas where other changes (e.g., swelling of the arcuate nerve fiber layer) have been already described. In theory, superficial vessel density modifications may be due to the direct surgical trauma to the inner retina, where the superficial plexus is contained, during the ILM grasping
Conjunctival characteristics in primary open-angle glaucoma and modifications induced by trabeculectomy with mitomycin C: an in vivo confocal microscopy study
No full textOBJECTIVES: To evaluate the microscopic epithelial features seen with in vivo confocal microscopy (IVCM) of bulbar conjunctiva in glaucomatous patients undergoing trabeculectomy with mitomycin C in order to elucidate modifications.
METHODS: Fifteen eyes of 15 consecutive Caucasian patients affected with primary open-angle glaucoma (POAG) undergoing trabeculectomy and 10 eyes of 10 glaucomatous patients (controls) under medical therapy were enrolled. Eyes were examined using a digital confocal laser-scanning microscope (HRT II Rostock Cornea Module) at baseline and after 6 weeks. The mean microcyst density (MMD: cysts/mm(2)) and microcyst area (MMA: mum(2)) were the main outcome measurements.
RESULTS: Before surgery, the mean intraocular pressure (IOP) was 25.1 (SD 3.2) mm Hg. MMD and MMA were 22.4 (11.9) and 4696.0 (3608.1), respectively. After trabeculectomy, the mean IOP was 16.1 (1.7) mm Hg. A marked increase in both MMD and MMA, with values of 103.1 (22.6) and 29 489.3 (12 954.9), respectively, was observed. In the control group at baseline, the mean IOP was 15.7 (1.9) mm Hg, and the microcyst parameters did not differ from eyes undergoing filtering surgery. After 6 weeks, IOP and microcysts parameters did not show any significant modifications.
CONCLUSIONS: Conjunctival epithelial microcysts were demonstrable in glaucomatous eyes under medical therapy prior to trabeculectomy. The filtering procedure increased microcysts density and surface at bleb site indicating a marked postsurgical enhancement of aqueous filtration across conjunctiva
Optical Coherence Tomography Angiography in the Multimodal Imaging Evaluation of Interferon-Associated Retinopathy: A Case Report
No full textThe authors present the case of a 59-year-old woman in treatment with interferon alfa-2b for stage IV melanoma and widespread metastases who presented with interferon-associated retinopathy. An ocular examination revealed multiple retinal cotton-wool spots and hard exudates. Interferon treatment was suspended. The patient was followed up for 5 months following the baseline visit by means of en face optical coherence tomography (OCT), spectral-domain OCT, and OCT angiography. Multimodal imaging was useful in the follow-up of this condition, permitting the characterization of all the lesions hallmarking the interferon-retinopathy and showing that this illness was related to a reduction of the retinal vascular perfusion
The efficacy of an echo-contrast agent in ultrasound power doppler evaluation of sinovitis: comparison with magnetic resonance imaging with and without contrast medium
No full textADULT-ONSET FOVEOMACULAR VITELLIFORM DYSTROPHY EVALUATED BY MEANS OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: A Comparison With Dry Age-Related Macular Degeneration and Healthy Eyes
No full textPURPOSE: To investigate alterations of superficial and deep retinal vascular densities, as well as of choroidal thickness, in patients affected by adult-onset foveomacular vitelliform dystrophy (AOFVD).
METHODS:
A total of 22 eyes (15 patients) affected by AOFVD were recruited in the study. Furthermore, 20 eyes of 20 healthy subjects and 20 eyes of 18 patients affected by intermediate dry age-related macular degeneration (AMD) were enrolled. All patients underwent a complete ophthalmologic examination, including optical coherence tomography angiography. Outcome measures were superficial vessel density, deep vessel density, and choroidal thickness.
RESULTS:
Parafoveal superficial vessel density was increased in patients with AOFVD compared with the AMD group (50.6 ± 4.3% and 46.3 ± 4.3%, respectively, P = 0.016). Parafoveal deep vessel density was 57.9 ± 6.4% in patients with AOFVD, 52.2 ± 3.8% in patients with AMD, and 52.7 ± 6.0% in healthy controls (P = 0.006 and P = 0.035, respectively, after comparison with the AOFVD group).
CONCLUSION:
We demonstrated that both superficial and deep vessel densities were significantly increased in patients with AOFVD, after the comparison with intermediate patients with AMD. These findings suggest that the pathogenic mechanisms in AOFVD are different from those in AMD and that optical coherence tomography angiography could be useful in differentiate early stages of these two diseases
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