147 research outputs found
Vital seeds: an assemblage approach to seed production and ownership
No full textPresented at the Environmental justice in the Anthropocene symposium held on April 24-25, 2017 at the Lory Student Center, Colorado State University, Fort Collins Colorado. This symposium aims to bring together academics (faculty and graduate students), independent researchers, community and movement activists, and regulatory and policy practitioners from across disciplines, research areas, perspectives, and different countries. Our overarching goal is to build on several decades of EJ research and practice to address the seemingly intractable environmental and ecological problems of this unfolding era. How can we explore EJ amongst humans and between nature and humans, within and across generations, in an age when humans dominate the landscape? How can we better understand collective human dominance without obscuring continuing power differentials and inequities within and between human societies? What institutional and governance innovations can we adopt to address existing challenges and to promote just transitions and futures?Includes bibliographical references.This paper is a think piece which attempts to examine the complexities of holistic research in a brief space. I outline a theoretical positioning for environmental study based in assemblage thinking, a sometimes contentious (Hornborg 2017), but useful approach. I then demonstrate the kind of inquiry by utilizing this assemblage approach in order to explore and critique discursive-legal issues in US patent and PVPA certification legislation. The end-goal of the project is to begin exploring how assemblage thinking within environmental justice scholarship could imagine a more just ecologic future
Corrigendum to âResponse to: Mitochondrial neuropathy affects peripheral and cranial nerves and is primary or secondary or bothâ [Neuromuscular Disorders 26/8 (2016) 549](S0960896616302899)(10.1016/j.nmd.2016.06.007)
No full textThe authors regret that the order of the first and last names was listed incorrectly in the above letter. The correct order for the authors' names is: Michelangelo Mancuso, Daniele Orsucci, Corrado Angelini, Enrico Bertini, Claudio Bruno, Valerio Carelli, Giacomo P. Comi, Massimiliano Filosto, Costanza Lamperti, Maurizio Moggio, Tiziana Mongini, Isabella Moroni, Paola Tonin, Antonio Toscano, Gabriele Siciliano, on behalf of the Nation-wide Italian Collaborative Network of Mitochondrial Diseases. Moreover, as this was a letter, only the affiliation of the corresponding author (M. Mancuso) was given. The corresponding author's address is not the affiliation for all other authors except for Daniele Orsucci and Gabriele Siciliano who share the same affiliation: Department of Clinical and Experimental Medicine, Neurological Institute, University of Pisa, Pisa, Italy. The authors would like to apologise for any inconvenience caused
Introductory notes to a grammar of Cahuilla : [to appear in Linguistic Studies offered to Joseph Greenberg on the occasion of his 60th birthday]
No full textThese notes grew out of my preoccupation with writing a grammar of a particular language, Cahuilla, which is spoken in Southern California and belongs to the Uto-Aztecan family. [...] The Introduction to the Grammar as a whole – of which two sections are reproduced here in a modified version – tries to integrate the synoptic views of the different chapters into a series of comprehensive statements. The statements cluster around two topics: 1. A presentation of Cahuilla as a type of language. 2. Remarks on writing a grammar
Development of enabling technologies for single cell analysis with mass spectrometry
No full textMass spectrometry (MS) is an effective methodology for untargeted, label-free, highly multiplexed analyses of trace compounds based on their mass-to-charge ratios. For biological applications, these properties have generated interest in determining biomarkers of diseased states, detecting drug compounds and metabolites, and observing previously unknown chemical messengers. Recent developments in instrumentation have provided exquisite sensitivity with robust performance. A growing field of single cell chemical analysis has arisen around these figures of merit. While early reports utilized manual isolation and extraction, recent developments in high-throughput sampling have enabled the examination of large populations of cells. One such method includes the analysis of dispersed single cells on a flat surface. When cells are randomly seeded onto the surface, their locations have to be determined by optical imaging to direct acquisition of isolated cells efficiently. A variety of microprobe ionization sources are suitable for such analyses, though smaller probe footprints can utilize more densely seeded samples.
This dissertation describes two technologies for performing single cell analysis with mass spectrometry. The first, synchronized desorption electrospray ionization (DESI), facilitates ambient ionization MS with high mass resolution, low duty cycle mass analyzers. The initial report utilized synchronized DESI for mass spectrometry imaging, but interrupting the desorption plume would be useful for profiling several locations on a surface in an arbitrary order for single cell analysis. The second methodology utilizes microscopy images to guide MS profiling. Specifically, image analysis software, called microMS, was developed to perform cell finding and correlate optical coordinates with the physical coordinates in a mass spectrometer. Since most of the functionality of microMS is decoupled from the mass spectrometer, the workflow can be easily extended to a variety of instruments. Using matrix-assisted laser desorption/ionization (MALDI) time of flight (TOF)-MS, rodent pancreatic islet cells were investigated and heterogeneous peptide processing was detected at the single cell level. With secondary ion mass spectrometry, disparate tissue from the mammalian nervous system was differentiated and further stratified into separate populations. A unique feature of such analyses is that only a fraction of the sample is consumed and the location of a cell is constant once the sample is dried. This property greatly simplifies sequential, follow-up analysis. As an example, MALDI-TOF-MS was utilized to rapidly screen a population of islet cells to select alpha and beta cell types. The locations of those cells were then targeted for liquid microjunction extraction in order to examine their metabolite profiles with capillary electrophoresis-MS. Finally, while microscopy-guided MS profiling is accurate enough to target single cells, the methodology is flexible enough to analyze much larger samples, including tissue sections or bacterial colonies. As an application, natural product mutant libraries were screened directly from E. coli colonies using microMS. The suite of technologies and protocols described increases the applicability of many mass spectrometers to characterize a range of cells, colonies and similar objects for their chemical composition.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-05-01The student, Troy Comi, accepted the attached license on 2017-04-19 at 08:42.The student, Troy Comi, submitted this Dissertation for approval on 2017-04-19 at 08:48.This Dissertation was approved for publication on 2017-04-19 at 11:28.DSpace SAF Submission Ingestion Package generated from Vireo submission #10885 on 2017-08-10 at 14:31:48Made available in DSpace on 2017-08-10T19:52:12Z (GMT). No. of bitstreams: 3
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Previous issue date: 2017-04-19Embargo set by: Colleen Fallaw for item 102655
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Rethinking Control: Complexity in Agri-environmental Governance Research
No full textFirst paragraph:
Discourse on governance always faces the challenge of describing, and usually simplifying, the many voices who formally and informally participate in controlling, and therefore governing, shared outcomes for community members both locally and globally (Callon, Lascoumes, & Barthe, 2009). Environmental and agricultural governance faces this problem redoubled, as outcomes and governing bodies cross boundaries between species, affecting humans and nonhumans, animals and otherwise (Latour, 2017; Tsing, 2015). Addressing incoherence, difference, and complexity (Law, 2004) is a general research concern among social scientists who wish to avoid subjugating otherwise marginalized participants. By looking to measurements and research methods that arise from studies outside politics and economics, actors that would be hidden or silenced by political economic critiques and metrics may become visible. For engaged governance research, the benefits of this are clear: a more inclusive social science of governing stakeholders. This edited collection brings together diverse international scholarship in agri-food social science research to rethink the framework of agri-environmental governance. The editors frame the selection of essays as efforts to look to the mess of stakeholders, legislators, growers, eaters, food councils, lands, crops, assessments, and so forth as a governing assemblage. By doing this, researchers are able to explore meanings and social experiences that diverge (although do not entirely separate) from neoliberal (e.g., large, corporate) frameworks in ways that complicate the governing underpinnings that are continually at work (re)territorializing the world of agriculture, food, and environment policy and praxis...
Do Farmers Know Better? Exploring Innovation, Environmental Change, and Rural Livelihoods among US Hop Growers
No full textThis dissertation examines the paired social and environmental impacts of farmer-driven innovation through on-site interviews and participant observation with US hop growers. Together, these three research articles make an important contribution to environmental and rural sociology along with science and technology studies by showing how farmer-directed science can support more sustainable futures. While most large-scale US farmers are already technologically and economically “locked” into unsustainable practices, hop growers break this mold, using profits resulting from the craft beer boom to innovate their own implements and further develop their own on-farm breeding programs. Using qualitative methods, I examine these growers as a case study, revealing that farmer-driven innovation can result in improvements to environmental sustainability and adaptive capacity. However, I also find that without policy interventions, small farmers are excluded from profitable new technologies and laborers still face unequal exposure to environmental and financial risks. The three articles each examine different aspects of this dynamic: Chapter 2 overviews the contemporary state of Yakima Valley hop farming and describes hop growers’ efforts to “decommodify” hops. Chapter 3 is a “deep dive” study into knowledge-politics involved in producing new genetics at the largest farmer directed hop breeding operation in the US (HBC). Chapter 4 examines the small farmers that operate as an alternative to the large neo-plantation farms indicative of the new US and Yakima-focused hop marketplace
Rethinking Control: Complexity in Agri-environmental Governance Research
No full textFirst paragraph:
Discourse on governance always faces the challenge of describing, and usually simplifying, the many voices who formally and informally participate in controlling, and therefore governing, shared outcomes for community members both locally and globally (Callon, Lascoumes, & Barthe, 2009). Environmental and agricultural governance faces this problem redoubled, as outcomes and governing bodies cross boundaries between species, affecting humans and nonhumans, animals and otherwise (Latour, 2017; Tsing, 2015). Addressing incoherence, difference, and complexity (Law, 2004) is a general research concern among social scientists who wish to avoid subjugating otherwise marginalized participants. By looking to measurements and research methods that arise from studies outside politics and economics, actors that would be hidden or silenced by political economic critiques and metrics may become visible. For engaged governance research, the benefits of this are clear: a more inclusive social science of governing stakeholders. This edited collection brings together diverse international scholarship in agri-food social science research to rethink the framework of agri-environmental governance. The editors frame the selection of essays as efforts to look to the mess of stakeholders, legislators, growers, eaters, food councils, lands, crops, assessments, and so forth as a governing assemblage. By doing this, researchers are able to explore meanings and social experiences that diverge (although do not entirely separate) from neoliberal (e.g., large, corporate) frameworks in ways that complicate the governing underpinnings that are continually at work (re)territorializing the world of agriculture, food, and environment policy and praxis...
Letter to the Editor Regarding: A Comprehensive Review on Copemyl®.
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International insolvency law
No full textInternational Insolvency Law Key words: COMI, Insolvency regulation, insolvency, bankruptcy, forum shopping In today's globalized world, proceedings with an international element have become more and more important. This work deals with an important sector of private international law - international insolvency law. Owing to the breadth of the topic, the author has chosen to focus specifically on issues surrounding COMI (Centre of Main Interests) in the European context in conjunction with Council Regulation (EC) no. 1346/2000 on insolvency proceedings dated 29 May 2000 and its amendment in 2015. In addition to the description of the general parameters of European insolvency regulations he refers to the discussion regarding the advantages and disadvantages of COMI as the main factor for the determination of a court's jurisdiction for the initiation and conduct of insolvency proceedings with an international element, and tries to show (with references to several judgments of the European Court of Justice and national courts - among them the Czech courts) both the development of its application in practice and the development of the definition of COMI itself and criteria for assessment. In first chapters author gives the overview of theoretical grounds of the cross- border insolvency and shows the..
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