243 research outputs found
Supplemental_Material – Supplemental material for Effects of quadriceps muscle neuromuscular electrical stimulation in living donor liver transplant recipients: phase-II single-blinded randomized controlled trial
No full textSupplemental material, Supplemental_Material for Effects of quadriceps muscle neuromuscular electrical stimulation in living donor liver transplant recipients: phase-II single-blinded randomized controlled trial by Masatoshi Hanada, Akihiko Soyama, Masaaki Hidaka, Hiroki Nagura, Masato Oikawa, Ayumi Tsuji, Karina Tamy Kasawara, Sunita Mathur, W Darlene Reid, Mitsuhisa Takatsuki, Susumu Eguchi and Ryo Kozu in Clinical Rehabilitation</p
Supplemental Material - Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review
No full textSupplemental Material for Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review by John M Nicholson, Camila E Orsso, Sahar Nourouzpour, Brenawen Elangeswaran, Karan Chohan, Ani Orchanian-Cheff, Lee Fidler, Sunita Mathur and Dmitry Rozenberg in Chronic Respiratory Disease</p
sj-docx-1-pit-10.1177_15269248221145039 - Supplemental material for A Qualitative Study of the Perspectives of Healthcare Professionals on Features of Digital Health Interventions to Support Physical Activity in Solid Organ Transplant Recipients
No full textSupplemental material, sj-docx-1-pit-10.1177_15269248221145039 for A Qualitative Study of the Perspectives of Healthcare Professionals on Features of Digital Health Interventions to Support Physical Activity in Solid Organ Transplant Recipients by Lauren Handler, Paula Jaloul, Jessica Clancy, Brittany Cuypers, Jayme Muir, Julia Hemphill, Tania Janaudis-Ferreira, Chaya Gottesman, Lisa Wickerson, Mike Lovas, Joseph A. Cafazzo and Sunita Mathur in Progress in Transplantation</p
Supplemental Material - Clinical implications of frailty assessed in hospitalized patients with acute-exacerbation of interstitial lung disease
No full textSupplemental Material for Clinical implications of frailty assessed in hospitalized patients with acute-exacerbation of interstitial lung disease by Marine Van Hollebeke Karan Chohan, Colin Adams, Jolene H Fisher, Shane Shapera, Lee Fidler, Ewan C Goligher, Tereza Martinu, Lisa Wickerson, Sunita Mathur, Lianne G Singer, W Darlene Reid and Dmitry Rozenberg in Chronic Respiratory Disease.</p
Weekend physiotherapy practice in community hospitals in Canada
No full textAffiliated institutions include: Univeristy of Toronto (C. Ellerton, S. Mathur, D. Brooks)Purpose: The objectives of this study were: 1) to describe the provision of weekend physiotherapy services in acute care community hospitals across Canada, and 2) to describe regional availability of these services. Method: Questionnaires were mailed to acute care community hospitals (institutions with > 100 inpatient beds, excluding psychiatric, mental health, paediatric, rehabilitation, tertiary and long term care facilities) across Canada from January to April, 2010. Results: Of 146 hospitals deemed eligible, 71% responded. Weekend physiotherapy service was offered at 69% of community hospitals overall, but this rate varied: =75% in all regions except Quebec (30%). Services differed in availability between Saturdays, Sundays and holidays, both in number of physiotherapists and hours served (K-W, p < 0.02, for each) and were largely compensated via time in lieu. Conclusions: Regional variation exists in access to weekend physiotherapy service in Canada. Further research is required to address the efficacy of weekend physiotherapy services for different patient groups to inform what constitutes appropriate frequency of weekend physiotherapy care in the community setting.Dina Brooks is supported by a Canada Research Chai
Life of Indians in the west as reflected in short stories by Sunita Jain
No full textThe main goal of the thesis is to evaluate the contribution of the short stories written by Hindi writer, Sunita Jain concerning the cultural differences between the Western and the Indian cultures and the lives of Indian people within the diaspora in the United States. The thesis opens with a brief introduction of the history of the Indian immigration to the United States of America and to England. This historical background is necesarry for understanding the basic elements of what follows. The thesis continues with the description of the main differences between the Western culture and the Indian culture. The content is focused towards the observations highlighted in the selected works by Sunita Jain. The chapter also raises questions on what it means to be an Indian in the world today and how the Indians deal with the balance of spirituality and materialism on home soil. The penultimate chapter, chapter three, looks at the life of Sunita Jain and describes the crucial moments that have affected her writings. The final chapter describes the life of the heros in Sunita Jain's short stories, that are placed in USA or after they returned to India from USA. The chapter also examines the cultural differences as they were grasped by the author, it deals with the common life they lead and compares it to the one..
Life of Indians in the west as reflected in short stories by Sunita Jain
No full textThe main goal of the thesis is to evaluate the contribution of the short stories written by Hindi writer, Sunita Jain concerning the cultural differences between the Western and the Indian cultures and the lives of Indian people within the diaspora in the United States. The thesis opens with a brief introduction of the history of the Indian immigration to the United States of America and to England. This historical background is necesarry for understanding the basic elements of what follows. The thesis continues with the description of the main differences between the Western culture and the Indian culture. The content is focused towards the observations highlighted in the selected works by Sunita Jain. The chapter also raises questions on what it means to be an Indian in the world today and how the Indians deal with the balance of spirituality and materialism on home soil. The penultimate chapter, chapter three, looks at the life of Sunita Jain and describes the crucial moments that have affected her writings. The final chapter describes the life of the heros in Sunita Jain's short stories, that are placed in USA or after they returned to India from USA. The chapter also examines the cultural differences as they were grasped by the author, it deals with the common life they lead and compares it to the one..
Peripheral Skeletal Muscle Structure and Contractile Function in Adults with Cystic Fibrosis
No full textGenetic mutations in cystic fibrosis (CF) result in dysfunction of the CF transmembrane conductance regulator (CFTR) protein. As people with CF are living longer, issues regarding skeletal muscle performance have become more prominent. Limb muscle structure and contractile function in adults with CF are not well characterized and their associations with patient demographics and clinical features have not been adequately evaluated. CFTR protein is expressed in human skeletal muscle, but its role is unknown. This thesis was undertaken to characterize limb muscle structure and contractile function in people with CF, to examine their associations with demographic and clinical variables in people with CF, and to delineate the impact of abnormalities of CFTR protein on skeletal muscle structure and contractile function in people with CF. A systematic review and meta-analysis (Study 1) found adults with CF to have thigh muscle atrophy, and a subgroup had quadriceps weakness. Also, adults with CF had lower handgrip strength, especially in females, and it was associated with lower lung function. A prospective study designed to investigate the association between CFTR protein dysfunction and muscle structure (Study 2) demonstrated no differential impact of the extent of diminished CFTR protein activity on quadriceps size or muscle quality, as determined by ultrasound measures. Upper and lower limb muscle strength, determined by dynamometry, and leg muscle power assessed with stair climb power test (Study 3) showed no relationships between CFTR protein dysfunction and impairment in muscle strength or muscle power. Nevertheless, quadriceps muscle contractility was found to be lower in people with severe CFTR protein dysfunction. In conclusion, adults with CF are confirmed to have impairment in their limb muscle size and muscle strength, and CFTR protein plays a role in muscle contractility, which needs to be confirmed with cellular and molecular studies in humans with CF. Future studies are needed to examine the implications of these results on ventilatory muscle contractility, and how CFTR modulator therapies affect muscle contractility in adults with CF. Furthermore, upper limb muscle structure and contractile function, and other aspects of muscles, e.g. muscle architecture, need further exploration in adults with CF.Ph.D
Muscle Matters: Understanding how Muscle Function Contributes to Reactive Stepping Performance
No full textMuscle weakness and balance control are two important predictors of fall risk. The main objective of this work was to determine how leg muscle function contributes to reactive stepping performance – a strategy used to recover balance. Studies 1-3 were conducted in young, healthy adults and study 4 was performed in individuals with chronic stroke. The first study demonstrated that force plate measures used to estimate foot-off and swing times of the stepping limb following a loss of balance had good to excellent between-session reliability. The second study highlighted unique function-specific increases in muscle activity following larger balance perturbations. Namely, the timing of muscle activation suggested that the modulation of medial gastrocnemius and biceps femoris was likely important for reducing forward momentum, propelling the swing limb forward, and applying braking forces at foot contact. In addition, increased muscle activity of the vastus lateralis and tibialis anterior likely contributed to earlier foot-off times and restabilization of the centre of mass following foot contact. The third study found that while most measures of muscle strength and explosive force were not related to reactive step timing, knee extensor explosive force was correlated with swing time. The last study revealed strong correlations between the average number of steps required to recover balance and knee flexor and extensor concentric peak torque in chronic stroke. Overall, the findings of this work suggest that muscle function contributes to reactive stepping performance, with the knee extensors having an important role particularly during restabilization. Variability in strength and balance control due to aging or neurological injury may accentuate these correlations to a greater extent and warrant further investigation.Ph.D
Skeletal Muscle Dysfunction in Lung Transplant Patients
No full textLung transplantation improves health-related quality of life (HRQL), daily function and survival for individuals with advanced lung disease. However, lung transplantation is now offered to older and more complex patients who are at a higher risk of skeletal muscle dysfunction; the implications of which remain uncertain. The overall objective was to assess how elements of muscle dysfunction (mass, strength and function) are associated with pre- and post-transplant physical function, HRQL, and clinical outcomes. We hypothesized that pre-transplant skeletal muscle dysfunction would be associated with impairments in pre-transplant HRQL, activities of daily-living (ADL), six-minute walk distance (6MWD), and worse post-transplant functional recovery with increased pre- and post-transplant mortality. Three studies targeting the pre- and post-transplant periods were undertaken. In study 1, a novel method of muscle mass quantification using computed tomography (CT) was retrospectively evaluated in 527 lung transplant candidates. CT muscle cross-sectional area in transplant candidates was 10% lower than age and sex-matched controls and independently associated with 6MWD, strength training volumes and post-transplant hospital length of stay (LOS), but no association was observed with pre- or post-transplant mortality. In study 2, muscle mass assessed with bio-electrical impedance, quadriceps strength, and function (Short Physical Performance Battery, SPPB) were prospectively evaluated in 50 lung transplant candidates. Quadriceps strength and SPPB were associated with pre-transplant HRQL, ADL, and 6MWD. Number of muscle deficits (mass, strength and/or function) was directly correlated with post-transplant hospital LOS, but not with delisting/mortality or post-transplant 6MWD. In study 3, the impact of pre-transplant skeletal muscle mass and function on post-transplant functional independence, HRQL, and 6MWD was evaluated in a select group of lung transplant recipients with prolonged mechanical ventilation (â Ľ 7 days). Age and intensive care unit (ICU) LOS were the only determinants of early post-transplant functional recovery, highlighting the importance of ICU-acquired morbidity. In summary, these studies demonstrate that skeletal muscle function is an important marker of pre-transplant daily function and predicts post-transplant hospital LOS, but is not a significant predictor of post-transplant function or mortality. Future studies should examine whether targeted rehabilitation strategies in the pre-transplant period may improve daily function and early post-transplant outcomes.Ph.D
- …
