373 research outputs found
Time course of action of three adenosine A1 receptor agonist with differing lipophilicity in rats: comparison of pharmacokinetic, haemodynamic and EEG effects
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Input-Output Economics: Theory and Applications - Featuring Asian Economies
No full textThijs ten Raa, author of the acclaimed text The Economics of Input–Output Analysis, now takes the reader to the forefront of the field. This volume collects and unifies his and his co-authors' research papers on national accounting, Input–Output coefficients, economic theory, dynamic models, stochastic analysis, and performance analysis. The research is driven by the task to analyze national economies. The final part of the book scrutinizes the emerging Asian economies in the light of international competition
Intra-patient variability in tacrolimus trough concentrations and renal function decline in pediatric renal transplant recipients
No full textPrytula AA, Bouts AH, Mathot RAA, van Gelder T, Croes LK, Hop W, Cransberg K. Intra-patient variability in tacrolimus trough concentrations and renal function decline in pediatric renal transplant recipients. Abstract: High intra-patient variability in TCL exposure is a risk factor for allograft loss and late acute rejection. We hypothesized that a higher intra-patient variability leads to a faster decline in GFR in pediatric renal transplant patients and that adolescents have a higher intra-patient variability due to poorer adherence. We included 69 children aged 3.518 yr who had undergone renal transplantation between April 1996 and May 2009 in two pediatric nephrology centers in the Netherlands. We analyzed TCL trough concentrations over a period of one yr and calculated TCL trough concentrations variability using VC. We investigated the correlation between the TCL trough concentrations variability and the decline in estimated GFR over four yr. The median intra-patient variability in TCL concentrations was 30.1% (range 8.677.6) and the mean GFR slope -3.8 mL/min/1.73 m2/yr. The VC correlated neither with the GFR slope, nor with the patients age. However, children with late acute rejection had higher VC (p = 0.045). We were unable to provide evidence that a high variability in TCL exposure leads to a faster decline in renal function, although children with late acute rejection have a higher variability in TCL exposure. Adolescents do not have a higher intra-patient variability in TCL trough concentrations than younger childre
Competitive Pressure on China: Factor Rewards Migration
No full textOur objective is to assess personal income under perfect competition, when factors are rewarded according to their productivities, and to contrast the ensuing distribution with the status quo.Competition will yield winners and losers, both in terms of factor claims and in terms of regions or provinces. Income differences will press people to migrate.To analyze this, we divide China into 30 input-output sectors and 27 provinces; we maximize domestic final demand, while preserving its proportions in each province, subject to material balances and factor constraints.The shadow prices to the constraints represent competitive commodity prices and factor rewards.Unskilled labor would stand to lose and, therefore, inequality would mount.The pressure on interprovincial migration would be enormous with 10 to 20% of the people on the road.The flipside is the great potential for improvement of the average standard of living.competition;income distribution;migration
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