3,143 research outputs found

    Di Negro e Dickens

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    A study of the relationship between C. Dickens and G.C. Di Negro during Dickens's stay in Genoa, with transcriptions of Dickens's unpublished letters to Di Negro

    EFFECTS OF 12 WEEKS OF ESSENTIAL AMINO ACIDS (EAA)-BASED MULTI-INGREDIENT NUTRITIONAL SUPPLEMENTATION ON MUSCLE MASS, MUSCLE STRENGTH, MUSCLE POWER AND FATIGUE IN HEALTHY ELDERLY SUBJECTS: A RANDOMIZED CONTROLLED DOUBLE-BLIND STUDY.

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    Objective: to counteract muscle mass, muscle strength and power loss during aging, and to study age-related change of neuromuscular manifestation of fatigue in relation to nutritional supplementation. Design: randomized controlled double-blind study. Setting: twice-daily consumption for 12 weeks of an Essential Amino Acids (EAA)-based multi-ingredient nutritional supplement containing EAA, creatine, vitamin D and Muscle Restore Complex®. Participants: 38 healthy elderly subjects (8 male, 30 female; age: 68.91±4.60 years; body weight: 69.40±15.58 kg; height: 1.60±0.09 m) were randomized and allocated in supplement (SUPP) or placebo (PLA) group. Mean Measurements: vitamin D blood level; Appendicular Lean Mass (ALM); Visceral Adipose Tissue (VAT); Maximal Voluntary Contraction (MVC) and Peak Power (PP); myoelectric descriptors of fatigue: Fractal Dimension and Conduction Velocity initial values (FD iv, CV iv), their rates of change (FD slopes, CV slopes) and the Time to perform the Task (TtT). Mean Results: significant changes were found in SUPP compared to baseline: vitamin D (+8.73 ng/ml; p<0.001); ALM (+0.34 kg; p<0.001); VAT (-76.25 g; p<0.001); MVC (+0.52 kg; p<0.001); PP (+4.82 W; p<0.001). Between group analysis (SUPP Vs. PLA) showed improvements: vitamin D blood levels (+11,72 ng/ml; p<0.001); Legs FFM (+443.7 g; p<0.05); ALM (+0.53 kg; p<0.05); MVC (+1.38 kg; p<0.05); PP (+9.87 W; p<0.05). No statistical changes were found for FD iv, CV iv, FD and CV slopes and TtT, either compared to baseline or between groups. Significant correlations between mean differences in SUPP group were also found. Conclusion: the study demonstrates that in healthy elderly subjects an EAA-based multi-ingredient nutritional supplementation of 12 weeks is not effective to change myoelectric manifestation of fatigue and TtT failure but can positively affect muscle mass, muscle strength, muscle power and VAT, counterbalancing more than one year of age-related loss of muscle mass and strength. Keywords: essential amino acids, creatine, vitamin D, antioxidants, muscle aging, muscle strength, muscle power, muscle fatigue.Objective: to counteract muscle mass, muscle strength and power loss during aging, and to study age-related change of neuromuscular manifestation of fatigue in relation to nutritional supplementation. Design: randomized controlled double-blind study. Setting: twice-daily consumption for 12 weeks of an Essential Amino Acids (EAA)-based multi-ingredient nutritional supplement containing EAA, creatine, vitamin D and Muscle Restore Complex®. Participants: 38 healthy elderly subjects (8 male, 30 female; age: 68.91±4.60 years; body weight: 69.40±15.58 kg; height: 1.60±0.09 m) were randomized and allocated in supplement (SUPP) or placebo (PLA) group. Mean Measurements: vitamin D blood level; Appendicular Lean Mass (ALM); Visceral Adipose Tissue (VAT); Maximal Voluntary Contraction (MVC) and Peak Power (PP); myoelectric descriptors of fatigue: Fractal Dimension and Conduction Velocity initial values (FD iv, CV iv), their rates of change (FD slopes, CV slopes) and the Time to perform the Task (TtT). Mean Results: significant changes were found in SUPP compared to baseline: vitamin D (+8.73 ng/ml; p<0.001); ALM (+0.34 kg; p<0.001); VAT (-76.25 g; p<0.001); MVC (+0.52 kg; p<0.001); PP (+4.82 W; p<0.001). Between group analysis (SUPP Vs. PLA) showed improvements: vitamin D blood levels (+11,72 ng/ml; p<0.001); Legs FFM (+443.7 g; p<0.05); ALM (+0.53 kg; p<0.05); MVC (+1.38 kg; p<0.05); PP (+9.87 W; p<0.05). No statistical changes were found for FD iv, CV iv, FD and CV slopes and TtT, either compared to baseline or between groups. Significant correlations between mean differences in SUPP group were also found. Conclusion: the study demonstrates that in healthy elderly subjects an EAA-based multi-ingredient nutritional supplementation of 12 weeks is not effective to change myoelectric manifestation of fatigue and TtT failure but can positively affect muscle mass, muscle strength, muscle power and VAT, counterbalancing more than one year of age-related loss of muscle mass and strength. Keywords: essential amino acids, creatine, vitamin D, antioxidants, muscle aging, muscle strength, muscle power, muscle fatigue

    Chiral Properties of Strong Interactions in a Magnetic Background

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    We investigate the chiral properties of QCD in presence of a magnetic background field and in the low temperature regime, by lattice numerical simulations of N_f = 2 QCD. We adopt a standard staggered discretization, with a pion mass around 200 MeV, and explore a range of magnetic fields (180 MeV)^2 \leq|e|B \leq (700 MeV)^2, in which we study magnetic catalysis, i.e. the increase of chiral symmetry breaking induced by the background field. We determine the dependence of the chiral condensate on the external field, compare our results with existing model predictions and show that a substantial contribution to magnetic catalysis comes from the modified distribution of non-Abelian gauge fields, induced by the magnetic field via dynamical quark loop effects

    Theta dependence of the deconfinement temperature in Yang-Mills theories

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    We determine the theta dependence of the deconfinement temperature of SU(3) pure gauge theory, finding that it decreases in presence of a topological theta term. We do that by performing lattice simulations at imaginary theta, then exploiting analytic continuation. We also give an estimate of such dependence in the limit of a large number of colors N, and compare it with our numerical results

    Phase diagram of Yang-Mills theories in the presence of a θ term

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    We study the phase diagram of non-Abelian pure gauge theories in the presence of a topological θ term. The dependence of the deconfinement temperature on θ is determined on the lattice both by analytic continuation and by reweighting, obtaining consistent results. The general structure of the diagram is discussed on the basis of large-N considerations and of the possible analogies and dualities existing with the phase diagram of QCD in the presence of an imaginary baryon chemical potential
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