495 research outputs found

    Correction to: Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan

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    The article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First without open access. After publication in volume 71, issue 4, page 711–722 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</jats:p

    A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy

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    東京女子医科大学博士(医学)博士(医学) 甲第762号(主論文の要旨、要約、審査結果の要旨、本文),著者名: Shota MITSUBOSHI, Jun HOMMA, Hidekazu SEKINE, Ryo TAKAGI, Tatsuya SHIMIZU, Masato KANZAKI,タイトル:A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy,掲載誌:Regenerative therapy (2352-3204),巻・頁・年:19巻 p.113~121(2022),著作権関連情報:© 2022 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.,DOI:10.1016/j.reth.2022.01.005doctoral thesi

    A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy

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    博士(医学) 甲第762号(主論文の要旨、要約、審査結果の要旨、本文),著者名: Shota MITSUBOSHI, Jun HOMMA, Hidekazu SEKINE, Ryo TAKAGI, Tatsuya SHIMIZU, Masato KANZAKI,タイトル:A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy,掲載誌:Regenerative therapy (2352-3204),巻・頁・年:19巻 p.113~121(2022),著作権関連情報:© 2022 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.,DOI:10.1016/j.reth.2022.01.00

    Literatuurstudie materiaaltransport door golven

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    Samenvatting van Japans onderzoek onder leiding van Horikawa en Homma in de periode 1960-197

    SENDAI VIRUS (PARAMYXOVIRIDAE)

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    Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species

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    AbstractWe have shown that mitochondrial c-Src regulates reactive oxygen species (ROS) production by phosphorylating the succinate dehydrogenase A of respiratory complex II (CxII). To elucidate the molecular mechanisms underlying ROS production regulated by c-Src in the CxII, we investigated the CxII protein complex derived from cells treated with Src family kinase inhibitor PP2. We identified flotillin-1 as a c-Src target that prevents ROS production from CxII. Phosphorylation-site analysis suggests Tyr56 and Tyr149 on flotillin-1 as sites for phosphorylation by c-Src. A comparison of cells expressing flotillin-1 and its phosphorylation defective mutants confirms the requirement for flotillin-1 phosphorylation for its interaction with CxII and subsequent reduction in ROS production. Our findings suggest a critical role of flotillin-1 in ROS production mediated by c-Src

    Global Trends in the Value of Author Order Across Medical Publications: A Cross‐Sectional Bibliometric Study

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    ABSTRACT This study aimed to analyse the value of author order across countries, within the ‘Medicine General Internal’ and ‘Surgery’ fields, to enhance transparency and fairness in academic evaluations, particularly in international collaborative research. A cross‐sectional bibliometric study was conducted using data from 2,845,748 papers published in 2022 across over 18,000 journals listed on Web of Science. The study focused on 124,736 papers from the ‘Medicine General Internal’ and ‘Surgery’ fields published in the top 19 countries. The analysis examined the position of the corresponding author relative to other co‐authors by country and specialty. Hierarchical clustering was applied to identify patterns and group countries based on author order. Three distinct clusters were identified with regard to the corresponding author's position. In Cluster A (South Korea, China and Taiwan), the corresponding author was often the last author. In Cluster B (India, Japan, Italy, Türkiye and Spain), the corresponding author was frequently the second author. Cluster C (the United States, England and Germany) included countries where the corresponding author was typically the first author. The findings underscore the need for clear, internationally accepted author order standards. Establishing such standards is crucial for promoting fairness, transparency and efficiency in international collaborative research and for ensuring equitable scientific communication
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