163 research outputs found
Kuhar, Michael interview conducted by Campbell/Spillane
No full textMichael J. Kuhar, Ph.D., is a neuroscientist, author, and Candler Professor of Neuropharmacology, School of Medicine at Emory University; Georgia Research Alliance Scholar; Senior Fellow, Center for Ethics at Emory; and Affiliate Researcher, Yerkes National Primate Research Center of Emory University. Dr. Kuhar has spent more than four decades as a neuroscience and neuropharmacology researcher. His studies have focused on the cellular and anatomical bases of addiction in order to pave the way for a new class of drugs to target addiction and obesity through a better understanding of CART peptides. These specific peptides are neurotransmitters that have been implicated in the regulation of feeding, body weight, drug reward and stress. With his more than 900 scientific publications, Dr. Kuhar is the most cited researcher at Emory. He has trained more than 60 students, research fellows and visitors, and he is the author of The Addicted Brain, Why we abuse drugs, alcohol, and nicotine (2012 Pearson Education/FT Press) and The Art and Ethics of Being a Good Colleague (2013 CreateSpace Independent Publishing Platform). His latest book is the basis for the "Michael Kuhar on Getting Collegial" article in the Spring 2014 issue of Emory Magazine. In 2011, Dr. Kuhar received the Nathan B. Eddy Memorial Award from the College on Problems of Drug Dependence (CPDD) to honor his lifetime achievements in research that have advanced the understanding of drug dependence. Sources: Yerkes National Primate Research Center, Emory University. http://www.yerkes.emory.edu/research/divisions/behavioral_neuroscience/kuhar_michael.html Accessed 26 Oct 2021 Dr. Michael J. Kuhar, Ph.D. website. https://www.michaeljkuhar.com/ Accessed 07 June 2023 “Michael J. Kuhar” Wikipedia. https://en.wikipedia.org/wiki/Michael_J._Kuhar Accessed June 7 2023.National Science Foundation; College on Problems of Drug Dependence; University of Michigan Substance Abuse Research Center; University of Michigan Institute for Research on Women and Gender; Wayne State University; University of Florida College of Liberal Arts and Scienceshttp://deepblue.lib.umich.edu/bitstream/2027.42/192820/1/03_Kuhar_M.mp3http://deepblue.lib.umich.edu/bitstream/2027.42/192820/2/Kuhar_Michael_bio.docxhttp://deepblue.lib.umich.edu/bitstream/2027.42/192820/3/Kuhar_Michael_photo.jpghttp://deepblue.lib.umich.edu/bitstream/2027.42/192820/4/Kuhar_Michael_transcript_24.doc
The 4th Earl of Dunraven, 1841–1926: a study of his contribution to the emerging Ireland at the beginning of the 20th century
No full textThe 4th earl of Dunraven was born in Adare in 1841 into one of the wealthiest landed families in Ireland. Succeeding to the title in 1871 he was the quintessential Irish peer, engrossing himself in travel and adventure, interspersed with occasional, but highly significant, contributions in the House of Lords.
His decision to contest the Croom division of Limerick County Council in 1899 marked the beginning of his public life, into which he packed, in twenty five short years, a lifetime of endeavour for Ireland, much of which ended in frustrating lack of success. The contest threw up many surprises, notably his tangle with Bishop O’Dwyer of Limerick over the want of higher education facilities for catholics, and an unavailing, but enterprising attempt, on behalf of his nationalist opponent, to snatch victory at the end of an unusual campaign. Though he never became chairman, which was one of his aims, he left his mark on council business, none more so than as an example to his fellow unionists that they, too, could and should aspire to serve their fellow countrymen on local bodies.
The second period of his active life showed remarkable acuity and resilience as he helped to steer the land conference of 1902 and the university imbroglio to successful conclusions. During that period, also, the trauma and difficulties attached, at that time, to the sale of his estate and the disposal of his village property in Croom, are manifested. Unusual for a landlord he, in conjunction with his new found soul mate and collaborator, William O’Brien, doggedly pressed for a resolution of the festering problem of the evicted tenants, the so-called walking wounded of the land war. One of his most endearing enterprises was his involvement in the resuscitated Irish tobacco industry but that venture, too, failed due to no fault on the part of the two pioneering entrepreneurs, Dunraven and Col Nugent Everard from County Meath.
The third part, taken chronologically, deals with matters political and was the least fruitful of his life’s work and yet had the most potential. His unrelenting unionism, a credo he adhered to until the early 1920s, coupled with his shifting of the political goalposts (he gave the land settlement precedence over home rule) earned him the undying antipathy of the Irish Party and the nationalist press. His proposals, in 1904, for wide administrative reform, under the banner of the Irish Reform Association, floundered on the narrow rock of devolution. Despised by the nationalists he failed to win over any appreciable number of unionists to the new policy of conciliation. He failed, also, to divert the Ulster unionists from their path of separation. Abhorring partition, he, more than anyone else, before and after the great war, continually suggested workable and practical remedies for Ireland’s ills, but they fell on deaf ears as, by then, Dunraven had become a nonentity, accentuated by his strong support, during the war years, firstly for recruiting and, later, his advocacy of conscription. A realist at heart, in the early 1920s, he accepted the establishment of the Irish Free State as the best solution available at that time.
This is the first attempt to chronicle the life-work of Dunraven, a worthy representative of a gallant band of Irishmen whose attempts to meaningfully contribute to the emerging Ireland of the first two decades of the last century were despised at the time, and neglected and unrecorded since.N
GenEO
No full textThe open source software GenEO, written in Python, includes two new families of preconditioners for symmetric positive definite linear systems. 1) First, the AWG preconditioners (for Algebraic-Woodbury-GenEO) have the feature of being algebraic \cite{zbMATH07846109,10.1007/978-3-030-95025-5_81}. By this, we mean that only the knowledge of the matrix A for which the linear system is being solved is required. Thanks to the GenEO spectral coarse space technique, the condition number of the preconditioned operator is bounded theoretically from above. This upper bound can be made smaller by enriching the coarse space with more spectral modes.The novelty is that, unlike in previous work on the GenEO coarse spaces, no knowledge of a partially non-assembled form of A is required. Indeed, the spectral coarse space technique is not applied directly to A but to a low-rank modification of A of which a suitable non-assembled form is known by construction. The extra cost is a second coarse solve in the preconditioner. 2) Second, the framework for Krylov subspace methods with adaptive multipreconditioning is implemented. Multipreconditiioning is a technique that allows to apply more than one preconditioner at each step. Domain decomposition is a natural application. Since a multipreconditioned iteration is more expensive than a classical iteration, it is advantageous to multiprecondition only when necessary. To this end, an adapativity scheme was proposed in \cite{zbMATH06601530} and is implemented in GenEO.GenEO uses Petsc4py and Dolfinx to solve 2D and 3D problems. Then, it is easy to compare this new family of preconditioners with those already defined in Petsc and see their impact on various problems with highly heterogeneous coefficients.@Article{zbMATH06601530, Author = {Spillane, Nicole}, Title = {An adaptive multipreconditioned conjugate gradient algorithm}, FJournal = {SIAM Journal on Scientific Computing}, Journal = {SIAM J. Sci. Comput.}, ISSN = {1064-8275}, Volume = {38}, Number = {3}, Pages = {a1896--a1918}, Year = {2016}, Language = {English}, DOI = {10.1137/15M1028534}, Keywords = {65F10,65N30,65N55}, zbMATH = {6601530}, Zbl = {1416.65087}}@Article{zbMATH07846109, Author = {Gouarin, Lo{\"{\i}}c and Spillane, Nicole}, Title = {Fully algebraic domain decomposition preconditioners with adaptive spectral bounds}, FJournal = {ETNA. Electronic Transactions on Numerical Analysis}, Journal = {ETNA, Electron. Trans. Numer. Anal.}, ISSN = {1068-9613}, Volume = {60}, Pages = {169--196}, Year = {2024}, Language = {English}, DOI = {10.1553/etna_vol60s169}, Keywords = {65F10,65N30,65N55}, URL = {etna.mcs.kent.edu/volumes/2021-2030/vol60/abstract.php?vol=60&pages=169-196}, zbMATH = {7846109}}@inproceedings{10.1007/978-3-030-95025-5_81,abstract = {The starting point for the algebraic preconditioner is to relax condition (1) by allowing symmetric, but possibly indefinite, matrices in the splitting of A.},address = {Cham},author = {Spillane, Nicole},booktitle = {Domain Decomposition Methods in Science and Engineering XXVI},editor = {Brenner, Susanne C. and Chung, Eric and Klawonn, Axel and Kwok, Felix and Xu, Jinchao and Zou, Jun},isbn = {978-3-030-95025-5},pages = {745--752},publisher = {Springer International Publishing},title = {Toward a New Fully Algebraic Preconditioner for Symmetric Positive Definite Problems},year = {2022}
GenEO
No full textThe open source software GenEO, written in Python, includes two new families of preconditioners for symmetric positive definite linear systems. 1) First, the AWG preconditioners (for Algebraic-Woodbury-GenEO) have the feature of being algebraic \cite{zbMATH07846109,10.1007/978-3-030-95025-5_81}. By this, we mean that only the knowledge of the matrix A for which the linear system is being solved is required. Thanks to the GenEO spectral coarse space technique, the condition number of the preconditioned operator is bounded theoretically from above. This upper bound can be made smaller by enriching the coarse space with more spectral modes.The novelty is that, unlike in previous work on the GenEO coarse spaces, no knowledge of a partially non-assembled form of A is required. Indeed, the spectral coarse space technique is not applied directly to A but to a low-rank modification of A of which a suitable non-assembled form is known by construction. The extra cost is a second coarse solve in the preconditioner. 2) Second, the framework for Krylov subspace methods with adaptive multipreconditioning is implemented. Multipreconditiioning is a technique that allows to apply more than one preconditioner at each step. Domain decomposition is a natural application. Since a multipreconditioned iteration is more expensive than a classical iteration, it is advantageous to multiprecondition only when necessary. To this end, an adapativity scheme was proposed in \cite{zbMATH06601530} and is implemented in GenEO.GenEO uses Petsc4py and Dolfinx to solve 2D and 3D problems. Then, it is easy to compare this new family of preconditioners with those already defined in Petsc and see their impact on various problems with highly heterogeneous coefficients.@Article{zbMATH06601530, Author = {Spillane, Nicole}, Title = {An adaptive multipreconditioned conjugate gradient algorithm}, FJournal = {SIAM Journal on Scientific Computing}, Journal = {SIAM J. Sci. Comput.}, ISSN = {1064-8275}, Volume = {38}, Number = {3}, Pages = {a1896--a1918}, Year = {2016}, Language = {English}, DOI = {10.1137/15M1028534}, Keywords = {65F10,65N30,65N55}, zbMATH = {6601530}, Zbl = {1416.65087}}@Article{zbMATH07846109, Author = {Gouarin, Lo{\"{\i}}c and Spillane, Nicole}, Title = {Fully algebraic domain decomposition preconditioners with adaptive spectral bounds}, FJournal = {ETNA. Electronic Transactions on Numerical Analysis}, Journal = {ETNA, Electron. Trans. Numer. Anal.}, ISSN = {1068-9613}, Volume = {60}, Pages = {169--196}, Year = {2024}, Language = {English}, DOI = {10.1553/etna_vol60s169}, Keywords = {65F10,65N30,65N55}, URL = {etna.mcs.kent.edu/volumes/2021-2030/vol60/abstract.php?vol=60&pages=169-196}, zbMATH = {7846109}}@inproceedings{10.1007/978-3-030-95025-5_81,abstract = {The starting point for the algebraic preconditioner is to relax condition (1) by allowing symmetric, but possibly indefinite, matrices in the splitting of A.},address = {Cham},author = {Spillane, Nicole},booktitle = {Domain Decomposition Methods in Science and Engineering XXVI},editor = {Brenner, Susanne C. and Chung, Eric and Klawonn, Axel and Kwok, Felix and Xu, Jinchao and Zou, Jun},isbn = {978-3-030-95025-5},pages = {745--752},publisher = {Springer International Publishing},title = {Toward a New Fully Algebraic Preconditioner for Symmetric Positive Definite Problems},year = {2022}
The 4th Earl of Dunraven, 1841–1926: a study of his contribution to the emerging Ireland at the beginning of the 20th century
No full textThe 4th earl of Dunraven was born in Adare in 1841 into one of the wealthiest landed families in Ireland. Succeeding to the title in 1871 he was the quintessential Irish peer, engrossing himself in travel and adventure, interspersed with occasional, but highly significant, contributions in the House of Lords.
His decision to contest the Croom division of Limerick County Council in 1899 marked the beginning of his public life, into which he packed, in twenty five short years, a lifetime of endeavour for Ireland, much of which ended in frustrating lack of success. The contest threw up many surprises, notably his tangle with Bishop O’Dwyer of Limerick over the want of higher education facilities for catholics, and an unavailing, but enterprising attempt, on behalf of his nationalist opponent, to snatch victory at the end of an unusual campaign. Though he never became chairman, which was one of his aims, he left his mark on council business, none more so than as an example to his fellow unionists that they, too, could and should aspire to serve their fellow countrymen on local bodies.
The second period of his active life showed remarkable acuity and resilience as he helped to steer the land conference of 1902 and the university imbroglio to successful conclusions. During that period, also, the trauma and difficulties attached, at that time, to the sale of his estate and the disposal of his village property in Croom, are manifested. Unusual for a landlord he, in conjunction with his new found soul mate and collaborator, William O’Brien, doggedly pressed for a resolution of the festering problem of the evicted tenants, the so-called walking wounded of the land war. One of his most endearing enterprises was his involvement in the resuscitated Irish tobacco industry but that venture, too, failed due to no fault on the part of the two pioneering entrepreneurs, Dunraven and Col Nugent Everard from County Meath.
The third part, taken chronologically, deals with matters political and was the least fruitful of his life’s work and yet had the most potential. His unrelenting unionism, a credo he adhered to until the early 1920s, coupled with his shifting of the political goalposts (he gave the land settlement precedence over home rule) earned him the undying antipathy of the Irish Party and the nationalist press. His proposals, in 1904, for wide administrative reform, under the banner of the Irish Reform Association, floundered on the narrow rock of devolution. Despised by the nationalists he failed to win over any appreciable number of unionists to the new policy of conciliation. He failed, also, to divert the Ulster unionists from their path of separation. Abhorring partition, he, more than anyone else, before and after the great war, continually suggested workable and practical remedies for Ireland’s ills, but they fell on deaf ears as, by then, Dunraven had become a nonentity, accentuated by his strong support, during the war years, firstly for recruiting and, later, his advocacy of conscription. A realist at heart, in the early 1920s, he accepted the establishment of the Irish Free State as the best solution available at that time.
This is the first attempt to chronicle the life-work of Dunraven, a worthy representative of a gallant band of Irishmen whose attempts to meaningfully contribute to the emerging Ireland of the first two decades of the last century were despised at the time, and neglected and unrecorded since.N
Hardboiled American detective fiction: the novels of Ross Macdonald, Mickey Spillane & Robert B. Parker
No full textA careful, but brief study of the works of Dashiell Hammett and his immediate heir, Raymond Chandler, will reveal the potential of the hardboiled literary style, and the base from which we can measure, in greater detail, the contributions of the genre\u27s modern practitioners, particularly Ross Macdonald, Mickey Spillane, and the more contemporary Robert Parker. In evaluating these very different writers, we will consider three key elements of their fiction: 1) the nature of their detective-protagonist; 2) the nature of evil/crime: 3) the attitude of the hero/author towards women, love, and the family. In examining these sylistic features and the complexity and depth with which Hammett and Chandler dealt with them, we will have become more familiar with the potential style and content of this school, qualifying us to draw conclusions about the evolution of the genre since then, and to examine reasons for its enduring popularity
Images of Mary: Contemporary Variations
No full textArchived website and summary of exhibit in the Marian Library
Artists: Artists Joan M.Bohlig; Sandra Bowden; Lu Bro; Kit Cameron; Jerry Ellen Cannizzaro; David R.Coté; Lesia Dovzhenko; Robert Eustace; Nick Faraci; Timothy Farrer; Sharon Gill-Kolasinski; Christine Granger; Tatiana Grant; Christine H. Hayward; Marjorie Hennessy; Alice Hertel; Sr. Durie Kim, FMI; Rosemary A. Luckett; Patricia A. Lyle; Jean Marlow; Lynne Mcilvride Evans; Janet McKenzie; Melinda Morey; Serafina R. Nankervis; Madeline Panichelli; Aka Pereyma; Christina Pereyma; Joseph Pizzat; Sr. Mary Polutanovich; Bro. Jerome Pryor, SJ; Thomas Quirk; Diane Savino; Elizabeth Schultz; Bro. Don Smith, SM; Jan Solowianiuk; Anne Spillane Moher; Emil Stoenescu; Beverly Stoller; Melanie Twelves; Beverly Wirth; Suzanne M.Young
Exhibit dates: May 25 - July 5, 199
CDC bulletin, vol. IX, no. 11, November 1950
No full textOn cover: Toxicology of insecticides.Toxicology of insecticides / Wayland J. Hayes, Jr. -- The Status of fly resistance to insecticides in the Savannah area and its implications in the general problem of fly control / Kenneth D. Quarterman -- The newer economic poisons of use in disease control / William M. Upholt -- Insecticidal formulations / George W. Pearce, Mary B. Goette, Janet T. Spillane -- The Equipment Development Section of the Technical Development Services / Lawrence B. Hall -- The Radioactive Isotope Laboratory Unit at Technical Development Services / Jens A. Jensen -- -- Epidemic and disaster aid / Frank R. Shaw -- Part I. Disaster aid of long ago -- Part II. A Recent natural disaster at Texas City -- Part III. The Northwest flood (Columbia River Basin Flood - Spring 1948) -- -- Book review: Subtropical entomology -- Morbidity data.With the development of the Communicable Disease Center and the general expansion of Service personnel and activities following World War II, it became possible for the Service to render greater aid, not only in number of persons supplied but also in equipment and material furnished. Notable examples of this expanded service were the Texas City disaster, April 16, 1947, and the Northwest (Columbia River) flood in the spring of 1948.Federal Security Agency, U.S. Public Health Service, Communicable Disease Center, Atlanta, Georgia.36 numbered page
Assistive Technology
No full textCurrent federal legislation requires not only that students with disabilities be educated in the least restrictive setting but also that all students have equal access to a standards based curriculum. Providing this access can be a significant challenge for students who are unable to independently participate in traditional classroom activities. For these students, assistive technology supports may be the key to a successful general education placement. This chapter will discuss the process of designing and implementing assistive technology supports for a 2nd grade student with multiple physical, medical, and communication challenges.</jats:p
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