84 research outputs found

    Stadt-Theater Düsseldorf / Mignon : Dienstag, den 10. November 1903 ; Oper in 3 Akten

    No full text
    mit Benutzung des Goetheschen Romans "Wilhelm Meisters Lehrjahre" von Michel Carré und Jules Barbier, deutsch von Ferd. Gumbert. Musik von Ambroise Thomas. Spielleitung: Oskar Fiedler. Musikalische Leitung: Walter Rabl. Personen: Caesar Krause, Gustav Waschow, Ernst Bedau, Ernst Herz, Ernst Winter, Hugo Lazak, Hella Fichna, Marta Petrini. Im 1. Akt: Zigeunertanz, arrangiert von der Ballettmeisterin Emilie Strigel-Senberg, ausgeführt von dem BallettpersonalIn Fraktu

    Stadt-Theater Düsseldorf / Die Zauberflöte : Sonntag, den 13. Dezember 1903: abends 7 Uhr ; Oper in 2 Akten

    No full text
    von Emanuel Schikaneder. Musik von Wolfgang Amadeus Mozart. Spielleitung: Oskar Fiedler. Musikalische Leitung: Dr. Walter Rabl. Personen: Heinrich Gärtner, Caesar Krause, Alfons Schützendorf, Peter Kirschbaum, Ernst Bedau, Franz Grassegger, Hermine Förster, Anton Passy-Cornet, Marta Petrini, Fanny Pracher, Jula Bielfeld, Hella Fichna, Else Pöhn, Mela Wiels, Clotild Rechnitz, Clara Bellwidt, Charles Hein, Eduard Gisiger, Karl Linke, Hugo Lazak, Karl GerickeIn Fraktu

    Stadt-Theater Düsseldorf / Mignon : Sonntag, den 17. Januar 1904: abends 7 Uhr ; Oper in 3 Akten

    No full text
    mit Benutzung des Goethe'schen Romans "Wilhelm Meisters Lehrjahre" von Michel Carré und Jules Barbier, deutsch von Ferd. Gumbert. Musik von Ambroise Thomas. Musikalische Leitung: Dr. Walter Rabl. Personen: Caesar Krause, Gustav Waschow, Ernst Bedau, Ernst Herz, Ernst Winter, Hugo Lazak, Hella Fichna, Marta Petrini. Im 1. Akt: Zigeunertanz, arrangiert von der Ballettmeisterin Emilie Strigel-Senberg, ausgeführt von dem BallettpersonalIn Fraktu

    Stadt-Theater Düsseldorf / Die Zauberflöte : Sonntag, den 27. Dezember 1903: abends 7 Uhr ; Oper in 2 Akten

    No full text
    von Emanuel Schikaneder. Musik von Wolfgang Amadeus Mozart. Spielleitung: Oskar Fiedler. Musikalische Leitung: Dr. Walter Rabl. Personen: Heinrich Gärtner, Caesar Krause, Alfons Schützendorf, Peter Kirschbaum, Ernst Bedau, Franz Grassegger, Hermine Förster, Anton Passy-Cornet, Marta Petrini, Fanny Pracher, Jula Bielfeld, Hella Fichna, Else Pöhn, Mela Wiels, Clotild Rechnitz, Clara Bellwidt, Charles Hein, Eduard Gisiger, Karl Linke, Hugo Lazak, Karl GerickeIn Fraktu

    Glikokortykosteroidy a czynność komórek beta

    No full text

    Stadt-Theater Düsseldorf / Mignon : Sonntag, den 18. Oktober 1903, abends 7 Uhr ; Oper in 3 Akten

    No full text
    mit Benutzung des Goetheschen Romans "Wilhelm Meisters Lehrjahre" von Michel Carré und Jules Barbier. Deutsch von Ferd. Gumbert. Musik von Ambroise Thomas. Spielleitung: Oskar Fiedler. Musikalische Leitung: Walter Rabl. Personen: Caesar Krause, Gustav Waschow, Ernst Bedau, Ernst Herz, Ernst Winter, Hugo Lazak, Hella Fichna, Philine: Marta Petrini vom Stadttheater in Leipzig (Gastspiel auf Engagement). Im 1. Akt: Zigeunertanz, arrangiert von der Ballettmeisterin Emilie Striegel-Senberg, ausgeführt von dem BallettpersonalIn Fraktu

    The Impact of Obesity on the Excretion of Steroid Metabolites in Boys and Girls: A Comparison with Normal-Weight Children

    No full text
    Obesity in childhood is associated with several steroid changes, which result from excess body mass. The aim of this study was to evaluate steroid metabolism in children with obesity compared with those with normal weight, especially in relation to sex and puberty progress. We analyzed the clinical data of 191 children, aged between 5 and 18 years, with 115 affected (64 girls and 51 boys) and 76 unaffected (35 girls and 41 boys) by obesity. Routine clinical assessment and pubertal stage evaluation based upon Tanner’s scale were performed. In addition, to evaluate the impact of puberty, children with pre-adolescence and advanced puberty were divided into separate subgroups. Then, 24 h urine steroid excretion profiles were analyzed by gas chromatography/mass spectrometry. Significant differences in the excretion of steroid metabolites were found between normal weight children and children with obesity, especially in the prepubertal cohort. In this group, we observed enhanced activity in all the pathways of adrenal steroidogenesis. Raised excretion of mineralocorticoid derivatives such as tetrahydro-11-deoxycorticosterone, tetrahydrocorticosterone, and 5α-tetrahydrocorticosterone supported increased activity of this track. No significant differences were detected in the excreted free forms of cortisol and cortisone, while the excretion of their characteristic tetrahydro-derivatives was different. In pre-adolescent children with obesity, α-cortol and especially α-cortolone appeared to be excreted more abundantly than β-cortol or β-cortolone. Furthermore, in children with obesity, we observed elevated androgen excretion with an enhanced backdoor pathway. As puberty progressed, remarkable reduction in the differences between adolescents with and without obesity was demonstrated

    Upregulation of FOXO3 in New-Onset Type 1 Diabetes Mellitus

    No full text
    Forkhead box O (FOXO) transcription factors have been implicated in the development and differentiation of the immune cells. FOXO3 plays a crucial role in physiologic and pathologic immune response. FOXO3, cooperatively with FOXO1, control the development and function of Foxp3+ regulatory T cells (Treg). Since the lack of Treg-mediated control has fundamental impact on type 1 diabetes mellitus (T1DM) development, we investigated FOXO3 expression in patients with T1DM. FOXO3 expression was estimated in peripheral blood mononuclear cells (PBMCs) from newly diagnosed T1DM pediatric patients (n=28) and age-matched healthy donors (n=27) by reahavel-time PCR and TaqMan gene expression assays. Expression analysis revealed significant upregulation of FOXO3 in T1DM (P=0.0005). Stratification of the T1DM group according to the presence of initial diabetic ketoacidosis (DKA) did not indicate differences in FOXO3 expression in patients with DKA compared to a mild T1DM onset (P>0.05). In conclusion, overexpression of FOXO3 is correlated with the ongoing islet autoimmune destruction and might suggest a potential role for this gene in the pathogenesis of type 1 diabetes mellitus
    corecore