177 research outputs found
Introduction: Brigid Brophy
No full textAn introduction to the special issue of Contemporary Women's Writing on the author Brigid Brophy
Cleophas Dowd Collection-Brigid Matilda Foley Dowd Collins
No full textBrigid Matilda Foley Dowd Collins was the mother of Cleophas Dowd who lived in the Uinta Basin
Reforging Roma into New Soviet Gypsies
No full textGuest: Brigid O’Keeffe is an Associate Professor of History at Brooklyn College where she specializes in late imperial Russian and Soviet history. Her research interests include internationalism, Esperanto, selfhood, ethnicity, citizenship and everyday Soviet life. She’s the author of New Soviet Gypsies: Nationality, Performance, and Selfhood in the Early Soviet Union published by University of Toronto Press
Julie Haydon (Brigid), scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 1950
No full textPhoto of Julie Haydon (Brigid), in a scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 195
Using Human Brain Tissue to Characterise Primary Tauopathy in a New Zealand Cohort
No full textPrimary tauopathies are a group of neurodegenerative disorders characterised by the
pathological intracellular deposition of the tau protein. Pathologically, tauopathies are defined
by differences in tau isoform composition, morphology, cell-type specific inclusions, and
neuroanatomical distribution of tau pathologies. Despite having distinct pathological tau
signatures, the clinical presentation of tauopathies exist as a spectrum of disease
symptomology. To further complicate this, clinical syndromes often have significant symptom
overlap with multiple other tauopathies and even other neurodegenerative diseases.
This thesis identified and characterised a previously undescribed cohort of primary tauopathies
in the New Zealand Neurological Foundation Brain Bank. The first section of the thesis
identified the heterogeneous clinical and pathological population of primary tauopathy cases
by collecting clinical and pathological records. This revealed that few cases had the same
clinical and pathological diagnosis. This also showed that cases with the same clinical or
pathological diagnoses had diverse symptoms and variable pathological landscapes.
The second section of this thesis examined the abundance of tau neurofibrillary tangles (NFTs)
and their tau isoform expression across multiple brain regions. Primary tauopathies are
characterised by their predominant tau isoform expression. Furthermore, individual primary
tauopathies are pathologically diagnosed by the presence of morphological characteristic tau
lesions in specific regions. Quantitative analysis of tau using multiplex immunohistochemistry
(IHC) revealed a highly variable regional abundance of tau NFTs in the primary tauopathies.
Furthermore, this analysis revealed less isoform predominance than initially described in the
literature.
The last section of this thesis examined the glial lesions in the same cohort. Some primary
tauopathies also have a characteristic glial lesion that is crucial in the pathological diagnosis of
these diseases. Semi-quantitative analysis of cell-specific markers using multiplex-IHC
revealed a highly variable regional distribution, abundance, and morphological landscape of
glial lesions in primary tauopathies. Furthermore, this thesis showed that concomitant tau
pathologies were more abundant than previously described in the literature. This may
contribute to the primary tauopathies’ highly heterogeneous pathological and clinical
characteristics. Overall, this thesis has contributed key insights into the pathological landscape
of primary tauopathies in New Zealand
Julie Haydon (Brigid), scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 1950
No full textPhoto of Julie Haydon (Brigid), in a scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 195
Julie Haydon (Brigid), scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 1950
No full textColor slide photograph of Julie Haydon as Brigid, in a scene from Paul Vincent Carroll\u27s "Shadow and Substance," performed at Kingsbury Hall, University of Utah, May 10-13, 1950
RADIOCARBON DATING OF TECHNOLOGICAL TRANSITIONS: THE LATE HOLOCENE SHIFT FROM ATLATL TO BOW IN NORTHWESTERN SUBARCTIC CANADA – ERRATUM
No full textThe author affiliations appearing in Grund and Huzurbazar (2017) contain errors. The correct affiliations for the authors are as follows:
Brigid Sky Grund ▪ Anthropology Department, University of Wyoming, Department 3431, 1000 E. University Avenue, Laramie, Wyoming 82071-2001.Snehalata V. Huzurbazar ▪ Department of Biostatistics, West Virginia University, P.O. Box 9190, One Medical Center Drive, Morgantown WV 26506, USA.Additionally, the sentence on page 5 reading, “Catastrophic melting events create palimpsest the upper layers of ice (Meulendyk et al. 2012), potentially introducing taphonomic bias” inadvertently omitted two words. The correct sentence is “Catastrophic melting events create a palimpsest in the upper layers of ice, potentially introducing taphonomic bias.”The publisher apologizes for these errors.</jats:p
Julie Haydon (Brigid) and Joseph F. Catmull (Very Rev. Thomas Canon Skerritt), scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 1950
No full textPhoto of Julie Haydon (Brigid) and Joseph F. Catmull (Very Rev. Thomas Canon Skerritt), in a scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 195
Joseph F. Catmull (Very Rev. Thomas Canon Skerritt) and Julie Haydon (Brigid), scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 1950
No full textPhoto of Joseph F. Catmull (Very Rev. Thomas Canon Skerritt) and Julie Haydon (Brigid), in a scene from Paul Vincent Carroll\u27s "Shadow and Substance" performed at Kingsbury Hall, University of Utah, May 10-13, 195
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