327,972 research outputs found
Carotenoid accumulation in Dietzia maris NITD protects from macromolecular damage
No full textOver the past decades, nutraceuticals have attracted considerable interest because of their potential nutritional,
safety and therapeutic effects. Carotenoid molecules are potent nutraceuticals with an attractive colour and have
been shown to play crucial roles in the immune system and susceptibility of organisms to certain diseases. Reactive oxygen species (ROS) are considered to be a major threat to cellular components and lead to protein oxidation, lipid peroxidation and DNA damage. In the present study, canthaxanthin (CX), an orange-red keto-carotenoid, was extracted from Dietzia maris NITD. Carbonyl content measurement showed that the presence of CX
can prevent protein oxidation in D. maris NITD. The inhibition of protein oxidation in vitro revealed a high correlation coefficient of the extracted CX with positive controls. Both the linoleic acid model (IC50 = 932.48 μg/ml)
and the goat liver model experiments showed that CX can also inhibit lipid peroxidation in vitro. CX from D. maris
NITD was also proved to be effective in maintaining the observable intactness of a model DNA (pBR322). The
present study indicated that bacterial CX can be a useful bioactive compound to prevent oxidative damage incurred by cellular macromolecules in terms of pharmaceutical and nutraceutical aspects
Free jet millimeter wave spectroscopy of oxazolidinone compounds.
No full text2-Oxazolidinone (systematic name 1,3-oxazolidin-2-one) is a five-member heterocyclic ring exhibiting potential medicinal roperties. It is the pharmacophore of a class of antimicrobial agents which have a unique structure and good activity gainst Gram-positive pathogenic bacteria (e.g. linezolid, the first in clinical use 2-oxazolidinone antibiotic). Often the functionality of drugs is related to their conformational flexibility and ability to form non covalent interactions with ts urroundings. In order to understand how substitution affect these properties, a series of oxazolidone compounds has been studied by means of millimeter wave free jet Stark modulated absorption spectroscopy [1] and quantum mechanical
calculations. The achieved data will be presented. [1] C. Calabrese, A. Maris, L. Evangelisti, L.B. Favero, S. Melandri and W. Caminati, J. Phys. Chem. A, 117, 13712 (2013)
Il seminario permanente di studi e ricerche Fortuna maris
No full textIl contributo illustra nascita, obiettivi e composizione del Seminario permanente di studi e ricerche Fortuna maris istituito presso il Dipartimento di Studi Umanistici dell'Università degli Studi di Ferrara
Maris-France Avril : Itinéraires ď Hannibal en Gaule.
No full textBailly Antoine-S. Maris-France Avril : Itinéraires ď Hannibal en Gaule.. In: Revue de géographie alpine, tome 84, n°3, 1996. p. 130
Perspective-taking accuracy on a conceptually complex problem
No full textPerspective taking is the process of constructing an understanding of other persons' ways of conceptualizing and responding to situations. It involves the effortfulemployment of strategies that enable individuals to visualize, understand, anticipate, or
predict the perceptions, thoughts, feelings, or actions of others. This is achieved when the observer attempts to create a mental model that corresponds to another's own mental model of situations. The present research was designed in the context of a model that views perspective taking as a process of constructing a representation that varies in difficulty according to (a) the degree of similarity between the perspective taker and the target person and (b) the degree of similarity between the perspective taker's own life situation and that of the person whose perspective is taken (target situation) (Cutting &Chinn, 2007).
The perspective-taking problem provided to participants (college students enrolled in an educational psychology course) is unlike most prior research on perspective taking. It required them to predict how a conceptually novel target person (a villager living in Los Molinos, Peru) responded to a dissimilar situation (introduction of water purification practices). Multiple source documents on this topic provided opportunities for participants to seek out information and adjust their mental models accordingly. In addition, a variety of prompts and scaffolds to promote strategy use were
examined for their influence on perspective-taking accuracy. Results from this study showed that brainstorming multiple predictions facilitated initial prediction accuracy and that new information in critical source documents enhanced final prediction accuracy.
However, cognitive biases, such as rationalizing anomalous information and confirmation bias, interfered with correcting inaccurate predictions.Ph.D.Includes bibliographical references (150-163)by Maris F. Cuttin
Move Over, Roger Maris: Breaking Baseball's Most Famous Record
No full textThe dataset presented in this article, created by Jeffrey S. Simonoff of New York University, refers to game-by-game information for Mark McGwire and Sammy Sosa during summer of 1998. Roger Maris's long time Major League Baseball home run record was broken during this time frame. This data can be used to demonstrate graphical displays, categorical data analysis, analysis of variance, logistic regression, and smoothing methods for Poisson and binomial data. This is a great activity for a sports fan wanting to learn more about the statistics attached to his or her favorite sport
Título: Periplus maris Erythraei
No full text"Periplus Maris Erythraei" se atribuye equivocadamente a Arriano"Marca de ed: el frontispicioSign.: *\p7\s, A-Z\p8\s, 2A-2E\p5\s, 2F\p3\sTexto a 2 colCada obra con port. propiaFront. calc. "Joh Vanden Avele fecit" alusivo a las obras de ArrianoLas h. de grab. pleg. son un mapa de Eritrea "Erythraei sive rubri maris periplus olim ab Arriano descriptus nunc rero ab Abrah. Ostelio ex eodem delineatus. Amstelodami: Sumptibus Ioannis Iansohii" (entre pp. 2 y 3); una tabla que ilustra posiciones tácticas (entre pp. 96 y 97) y un mapa del Ponto Ensino (pp. 112 y 113)Grab. calc. entre pp. 1 y 97 que ilustran posiciones tácticasContiene : "Epicteti Stoici Enchiridion ... Paraphrasis graeca quam idem casabonus primus vulgarit ... subirarntur Epitecti Enchiridion ab Angelo politano graeco versum denique Epicteti Apuphegmata Estobaei Eclogis et fragmenta quaedam e M. Aurelio Antonino et Agellio colectu pp. 323 a 45
High Resolution Millimeter Wave Absorption Spectroscopy: from the laboratory data to the astronomical surveys
No full textConventional absorption spectroscopy is still the workhorse in high-resolution rotational laboratory spectroscopy.1 The data obtained from these kind of instruments are relevant for astronomical searches of complex molecules that represent excellent probes of the physical and chemical environments and history of the sources where they are detected.2 Nowadays, observations performed by the Atacama Large Millimeter Array (ALMA) open up new opportunities to reveal the chemical complexity of solar systems analogues. At the same time the huge amount of data collected and the extremely rich surveys represent a challenge for the astrochemistry community. To reach this goal, the spectroscopic know-how is fundamental in recognizing typical pattern lines due to multiple internal interactions and motions that cause complicated energy level schemes, since the resulting spectra will be rather difficult to predict theoretically, mainly in the sub-mm wave region. For this reason a strong interplay between laboratory spectroscopists and observational astronomers is increasingly required to be able to unravel the experimental data.
In this talk the features and the potential of the high resolution rotational spectroscopy technique will be pointed out, providing some results on different kind of molecules characterized by complex conformational landscapes. In particular, molecular spectra of potential astronomical interest will be presented, obtained using the free jet absorption millimeter wave and the free space cell absorption sub-mm wave spectrometers working at University of Bologna.3
References
[1] S. Brünken, S. Schlemmer, arXiv:1605.07456, 2016
[2] E. Herbst, E. F. van Dishoeck, Annu. Rev. Astron. Astrophys. 47, 427, 2009
[3] C. Calabrese, A. Maris, L. Evangelisti, L. B. Favero, S. Melandri, W. Caminati, J. Phys. Chem. A. 117, 13712, 201
Prediction of soft X-ray photo-electron/absorption spectra by ab initio calculations
No full textWe present two different theoretical approaches used to predict the photoelectron and the photoabsorption and discuss their accuracy by comparison with new experimental data.
The first method has been developed specifically for molecular inner shell excitation and ionization by Nobuhiro Kosugi since 1980 and implemented in the GSCF3 code. [1] Here the core ionized states and core-to-excited states transitions are solved within the Hartree-Fock approximation by explicitly taking into account the core hole. The excited orbitals to be singly occupied by the core-electron excitations are optimized within the STatic EXchange (STEX) method by freezing the core and the occupied valence HF orbitals of the corresponding core hole state. The calculations have been run for several molecules of biological interest (tyramine, tryptamine, tryptophol, barbituric and thiobarbituric acid) and the obtained XPS and NEXAFS spectra have been compared with the experimental results. [2]
The second approach has been developed by Angela Acocella in order to investigate the onset of the ionization dynamics in photoelectron spectroscopy with a quantum-mechanical time-dependent propagator used to evolve the electronic wavefunction [3] with the aim to correlate it to the spectral analysis. In practice, the high energy of the incoming photon triggers a complicated re-organization of the wavefunction where the usually dominant one-photon contribution is combined with all the possible many-photon contributions of the same energy, together with the continuum states of the ionized electron. The presented model proved to reproduce with reasonable accuracy both XPS and UPS spectra of the coronene molecule. [4]
[1] N. Kosugi and H. Kuroda, Chem. Phys. Lett. 74 (1980) 490.
N. Kosugi and H. Kuroda, Chem. Phys. Lett., 94 (1983) 377.
N. Kosugi, Theor. Chim. Acta, 72 (1987) 149.
[2] M. Coreno, V. Feyer, O. Plekan, K. C. Prince, R. Richter; W. Caminati, L. Evangelisti, B. M. Giuliano, A. Maris, S. Melandri, manuscript in preparation.
[3] A. Acocella, G. A. Jones and F. Zerbetto, J. Phys. Chem. A 110 (2006) 5164-5172.
A. Acocella, F. Carbone and F. Zerbetto, J. Am. Chem. Soc., 132 (2010) 12166-12167.
[4] A. Acocella, M. De Simone, F. Evangelista, M. Coreno and F. Zerbetto, paper submitted
Analysis of Yield Spreads on Commercial Mortgage-Backed Securities
No full textYield spreads on commercial mortgage-backed securities (CMBS) are defined as the difference between the yield on CMBS and the yield on comparable-maturity Treasuries. CMBS yield spreads declined dramatically from 1992 until 1997, then increased in 1998 and 1999. The relationship between CMBS yield spreads and other variables is estimated in an effort to explain recent trends. Results identify several variables that are related to yield spreads on both fixed-rate and variable-rate CMBS. However, even after controlling for other observable factors, the yield spread on CMBS still declined from 1992 until 1997, then increased each of the next two years. Possible explanations for this phenomenon are explored.
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