4 research outputs found
Genetics of pituitary adenomas
No full text© 2017 Neurology India, Neurological Society of India. Clinically relevant pituitary tumors presenting with altered hormonal secretion or mass effect represent a significant proportion of patients in endocrinology clinics. However, in recent years, these patients are also referred to clinical genetic services due to possible germline mutations causing syndromic or isolated pituitary adenomas. While somatic mutations have been identified in GNAS, USB8, PIK3CA, GPR101 and rarely in RAS, germline mutations have been identified in MEN1, cyclin dependent kinase inhibitor genes, AIP, DICER1, PRKAR1A, PRKACA, SDH genes and GPR101. In this review, we present a short overview of pituitary adenoma classifications, pituitary development and somatic and germline genetic changes identified in these adenomas
Probing the theological resources of a seventeenth‐century Timbuktu tārīkh : the Tārīkh al‐Sūdān and Ashʿarī kalām
No full textAbstract: The Tārīkh al-Sūdān, the so-called Tarīkh al-fattāsh, and the Notice historique, Timbuktu’s three famous seventeenth-century tārīkhs (chronicles) piqued the interest of Western scholars, travellers and colonial officials since the mid nineteenth-century. The first Western written works began to be produced at the end of the nineteenth century and burgeoned over the twentieth century with several large projects continuing into the present century, as recent as 2015. These works were primarily, though not exclusively, concerned with the authorship, sources, political properties of the tārīkhs, and Timbuktu’s social history. This article is interested in Muslim theology as a resource of the Tārīkh al-Sūdān, one the three tārīkhs. It focuses in particular on the precepts of Ashʿarī kalām (theology) of Sunni Islam as the key resource the author of the Tarīkh al-Sūdān
A point-free version of torsionfree classes and the Goldie torsion theory
No full textTorsion theories are a pinnacle in the theory of abelian categories. They are
a generalization of torsion abelian groups and in this generalization one of
the most studied is that whose torsionfree class consists of nonsingular
modules. To introduce the concept of singular interval we use the symmetric
idea of torsion theories, that is the torsion class determines the torsionfree
class and vice-versa, thus to introduce nonsingular intervals over an
upper-continuous modular complete lattice, (a.k.a idiom, a.k.a modular
preframe) we define the concept of \emph{division free} set. We introduce the
division free set of nonsingular intervals which defines a division set of
singular intervals in a canonical way. Several properties of division free sets
and some consequences of nonsingular intervals are explored allowing us to
develop a small part of a point-free nonsingular theory.Comment: 24 pages, corresponding [email protected]
