51 research outputs found
3-(Benzylthio)-1,2,4-triazine-5,6,-diamines: Promising molecules against chronic and neuropathic pain
No full textZur Chemie von 1,2,4-Triazin- und 1,2,4-Triazol-Analoga des Analgetikums Flupirtin
No full textDie vorliegende wissenschaftliche Abhandlung ist der Synthese und Reaktivität von Flupirtin-Analoga mit 1,2,4-Triazin-Gerüst und 1,2,4-Triazol-Körper gewidmet.The present thesis deals with the synthesis and reactivity of flupirtine analogs containing a 1,2,4-triazine or 1,2,4-triazole core
Analyses of sphingosine‐1‐phosphate in the context of transfusion: how much is in stored blood products and in patient blood?
No full textBACKGROUND: Sphingosine-1-phosphate (S1P) is a bloodborne lipid that regulates vascular tone and endothelial permeability. S1P concentrations are reduced in critically ill patients. As hematopoietic cells produce S1P, this study intends to investigate S1P concentrations in blood products during storage and in patient plasma after blood transfusion. STUDY DESIGN AND METHODS: S1P concentrations were measured in 83 red blood cell (RBC) units and 73 platelet concentrates (PCs) before and after storage. In addition, 26 critically ill patients who received one or two RBC units were recruited to measure S1P plasma levels before and three times within 24 hours after transfusion. RESULTS: The highest S1P concentrations were found in fresh PCs. S1P concentrations in PCs are reduced by 60% when stored at room temperature for 4 days, whereas in RBCs S1P concentrations remained stable when stored at 4°C within 35 days. S1P concentrations in PCs and RBCc were 2.5 to 6 times higher compared to patient plasma. Plasma S1P levels in critically ill patients, however, transiently decreased after transfusion of RBCs and recover to pretransfusion values within the following 24 hours. CONCLUSION: S1P concentrations in blood products are significantly higher compared to human plasma S1P levels, even though plasma S1P levels decreased after RBC transfusion in critically ill patients and reached pretransfusion values within 24 hours
ChemInform Abstract: Synthesis and Properties of 3,6-Diamino-Substituted 1,2,4-Triazin-5(2H)-ones.
No full textCyclization of N′,N′‐Disubstituted Anthranilic Hydrazides with 1,1′‐Oxalyldiimidazole to 4‐Amino‐2,3,4,5‐tetrahydro‐1H‐1,4‐benzodiazepin‐2,3,5‐triones.
No full textOxalylation of N‐Phenylanthranilic‐O‐alkylhydroxamates to 4‐Alkoxy‐2,3,4,5‐tetrahydro‐1H‐1,4‐benzodiazepine‐2,3,5‐triones.
No full textChemInform Abstract: Cyclic Oxalylation of Primary N-Substituted Anthranilamides: 1H-Benzo[e][1,4]diazepine-2,3,5(4H)-triones and 11a-Chlorobenzo[e]oxazolo[3,2-a] [1,4]diazepine-2,3,5,11(10H,11aH)-tetraones.
No full textA New Series of 2-Alkoxy(aralkoxy)-[1,2,4]triazolo[1,5-a]quinazolin-5-ones as Adenosine Receptor Antagonists
No full textChemInform Abstract: A New Series of 2-Alkoxy(aralkoxy)-[1,2,4]triazolo[1,5-a]quinazolin-5-ones as Adenosine Receptor Antagonists.
No full textThe Emergence of a New ‘Socialist’ Market Labour Regime in China
No full textChina’s transition to a market economy has been a process of basic institutional changes and institution building. The institutional change from a socialist labour regime (SLR) as one of the backbones upholding the traditional leninist system to a new ‘socialist’ market labour regime (SMLR) became particularly important for the success of economic and political reforms. This analysis is based on the analytical framework of regimes and makes use of the idea of path dependence. An ensemble of institutions, mutually interconnected and influencing each other, forms the regime and shapes its trajectory. Six institutions are identified to constitute the employment regime: (1) the system of social control, (2) the production system, (3) the system of industrial relations, (4) the welfare system, (5) the family order, and (6) the educational system. The SMLR is still characterised by its socialist past and differs from other varieties of transformation labour regimes and bears little resemblance to labour regimes in Western market economies.China, institutional change, transition, labour market, employment regime, path dependence theory, ASEAN, Mercosur, CMA
- …
