18 research outputs found
Sequence-Modification in Copoly(ester-Imide)s: A Catalytic/supramolecular Approach to Writing/reading Copolymer Sequence-Information
No full textCatalytic
ester-interchange reactions, analogous to mutation and recombination, allow new
sequence-information to be written, statistically, into NDI-based
poly(ester-imide) chains. Thus, insertion of the cyclic ester cyclopentadecanolide
("exaltolide") into an NDI-based homopolymer, and quantitative
sequence-exchange between two different homopoly(ester-imide)s, are catalysed
by di-n-butyl tin(IV) oxide. Emerging sequences are
identified at the triplet and quintet levels by 1H NMR analysis,
using supramolecular complexation of pyrene-d10
at the NDI residues to amplify the separation of resonances associated with
different sequences. In such systems, pyrene is able to act as a
"reader-molecule" by generating different levels of ring-current
shielding from the different patterns of supramolecular binding to all the NDI-centred
sequences of a given length
Recommended from our members
Sequence-modification in copoly(ester-imide)s: a catalytic/supramolecular approach to the evolution and reading of copolymer sequence-information
No full textCatalytic ester-interchange reactions, analogous to mutation and recombination, allow new sequence-information to be written, statistically, into NDI-based poly(ester-imide) chains. Thus, both insertion of the cyclic ester cyclopentadecanolide ("exaltolide") into an NDI-based homopolymer, and quantitative sequence-exchange between two different homopoly(ester-imide)s, are catalysed by di-n-butyl tin(IV) oxide. Emerging sequences are identified at the triplet and quintet levels using supramolecular complexation of pyrene-d10 at the NDI residues to amplify the separation of 1H NMR resonances associated with different sequences. In such systems, pyrene is able to act as a "reader-molecule" by generating different levels of ring-current shielding from the different patterns of supramolecular binding to all the NDI-centred sequences of a given length
Tackling Gender Inequality in STEM: Breaking Barriers and Building Futures
No full textThis symposium explores critical dimensions of gender inequality, diversity initiatives, and allyship in STEM (Science, Technology, Engineering, and Mathematics) workplaces. Drawing on empirical studies from the Netherlands, Denmark, and the United Kingdom, the presenters address key challenges in fostering inclusion in STEM fields.
A Contextualized Intersectional Approach to Inequality in STEM Work- A Review and Research Agenda
Author: Jessica Fiorelli; Hasselt University
Breaking Gender Barriers in STEM: A Comprehensive Approach to Combating Masculine Defaults
Author: Dejan Matlak; -
Author: Lena Knappert; Vrije Universiteit Amsterdam
Author: Yuval Engel; University of Amsterdam
Author: Danny Sanders; The Inclusion Studio
Allyship as World-Building: A Study of Women with Mental Health Issues in the UK STEM
Author: Elina Meliou; University of Southampton
Author: Weerahannadige Dulini Fernando; University of Warwick
Author: Krystal Wilkinson; Manchester Metropolitan University
Author: Gustavo Sanchez Munoz; -
The Lost Futures of Gender Diversity in STEM: The Politics of Time in Danish Diversity Initiatives
Author: Justine Grønbæk Pors;
Single-Site Binding of Pyrene to Poly(ester-Imide)s Incorporating Long Spacer Units: Prediction of NMR Resonance-Patterns from a Fractal Model
No full textSingle-Site Binding of Pyrene to Poly(ester-Imide)s Incorporating Long Spacer Units: Prediction of NMR Resonance-Patterns from a Fractal Model
No full textSingle-Site Binding of Pyrene to Poly(ester-Imide)s Incorporating Long Spacer Units: Prediction of NMR Resonance-Patterns from a Fractal Model
No full textCo-polycondensation
of the diimide-based diols N,N\u27-bis(2-hydroxyethyl)hexafluoro-isopropylidene-diphthalimide,
(HFDI), and N,N\u27-bis(2-hydroxy-ethyl)naphthalene-1,4,5,8-tetracarboxylic-diimide,
(NDI), with aliphatic diacyl chlorides ClOC(CH2)xCOCl (x = 5
to 8) affords linear copoly(ester-imide)s. Such copolymers interact with pyrene
via supramolecular binding of the polycyclic aromatic molecule at NDI residues.
This results in upfield complexation shifts and sequence-related splittings of
the NDI 1H NMR resonances, but gives a very different resonance-pattern
from the corresponding copolymer where x
= 2. Computational modelling of the polymer with x = 5 suggests that, in this system, each pyrene molecule binds to
just a single NDI residue rather than to an adjacent pair of NDI\u27s in a tight
chain-fold ("dual-site" binding) as found for x = 2. The new single-site binding model enables the pattern of 1H
NMR resonances for copolymers with longer spacers (x = 5 to 8) to be reproduced and assigned by simulation from sequence-specific
shielding factors based on the fractal known as the fourth-quarter Cantor set.
As this set also enables an understanding of dual-site binding systems, it
evidently provides a general numerical framework for supramolecular
sequence-analysis in binary copolymers
Single-Site Binding of Pyrene to Poly(ester-Imide)s Incorporating Long Spacerunits: Prediction of NMR Resonance-Patterns from a Fractal Model
No full textRecommended from our members
Single-site binding of pyrene to poly(ester-imide)s incorporating long spacer-units: prediction of NMR resonance-patterns from a fractal model.
No full textCo-polycondensation of the diimide-based diols N,N'-bis(2-hydroxyethyl)hexafluoroisopropylidene-diphthalimide, (HFDI), and N,N'-bis(2-hydroxy-ethyl)naphthalene-1,4,5,8-tetracarboxylic-diimide, (NDI), with aliphatic diacyl chlorides ClOC(CH2) x COCl (x = 5 to 8) affords linear copoly(ester-imide)s. Such copolymers interact with pyrene via supramolecular binding of the polycyclic aromatic at NDI residues. This interaction results in upfield complexation shifts and sequence-related splittings of the NDI 1H NMR resonances, but gives a very different final resonance-pattern from the copolymer where x = 2. Computational modelling of the polymer with x = 5 suggests that each pyrene molecule binds to just a single NDI residue rather than by intercalation between a pair of NDI's at a tight chain-fold, as was found for x = 2. The new single-site binding model enables the pattern of 1H NMR resonances for copolymers with longer spacers (x = 5 to 8) to be reproduced and assigned by simulation from sequence-specific shielding factors based on a type of fractal known as the last-fraction Cantor set. As this type of fractal also enables an understanding of pairwise binding systems, it evidently provides a general numerical framework for supramolecular sequence-analysis in binary copolymers
