86 research outputs found

    mRNA export and cancer

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    This PhD focuses on the relationship between mRNA export and cancer

    Testis-sparing surgery for testicular masses: current perspectives

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    Males who present with a palpable testis nodule are likely to have malignant germ cell tumor in > 90% of cases. Therefore radical orchiectomy remains the standard of care for intratesticular tumors. However, due to the recent developments of high-frequency probes in ultrasonography, the incidence of detecting a small non-palpable testis tumors is higher and higher. These lesions are thought to be benign in more than 60-80% of cases, thus a radical orchiectomy should be considered an overtreatment. In addiction to that, radical orchiectomy might cause infertility, psychological issues and endocrine disorders, hence an organ-sparing procedure in such cases should be pursued

    Re: Comprehensive Molecular Characterization of Muscle Invasive Bladder Cancer

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    Robertson AG, Kim J, Al-Ahmadie H, et al Cell 2017;171:540–56.e2
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