481 research outputs found
APPENDIX_I – Supplemental material for Explicit and implicit experience of own’s body in painful musculoskeletal disorders and rheumatic diseases: A scoping review protocol of available quantitative and qualitative evidence
No full textSupplemental material, APPENDIX_I for Explicit and implicit experience of own’s body in painful musculoskeletal disorders and rheumatic diseases: A scoping review protocol of available quantitative and qualitative evidence by Antonello Viceconti, Eleonora Maria Camerone, Deborah Luzzi, Matteo Pardini, Diego Ristori, Alberto Gallace and Marco Testa in SAGE Open Medicine</p
HOW ACCURATELY PRE-OPERATIVE PLANNING MATCHES THE ACHIEVED SURGERY: A FINITE ELEMENT STUDY
No full textPre-operative planning trains the surgeon in the workshop environment. The final objective of the early researches
along this line is to arrange a set of instruments to predict the primary stability in the pre-operative planning moving
toward a less and minimally invasive surgical technique. Nevetheless, even assuming a perfect surgical planning, there
is still the practical problem of correct positioning of the stem in the femur during surgery. An erroneous initial
positioning could lead to the implant instability promoting the ultimate failure of the implant [1,2]. Initial excessive
relative micromotions at the bone-implant interface may inhibit the bony in-growth and secondary long term fixation
[3,4]. To achieve a good level of primary stability the surgery technique play therefore a fundamental role.
Aim of the present study was to asses the sensitivity of the relative bone-implant micromotions, stresses and strains to
the surgical parameters as planned and achieved by the surgeon respectively before and after the operation. For this
purpose, the subject-specific finite element (FE) model of a cadaveric femur, accounting for patient and surgeon, was
derived from pre-operative and post-operative CT scans. The specific aim was to verify if finite element models based
on pre-clinical planning correctly match the achieved implant stability conditions
Uso di sensori indossabili in studi clinici: aspetti regolatori
No full text<p>This is a guideline document that the DARE consortium produced to assist the Italian Ethics Committees called to evaluating clinical studies involving wearable devices. As the level of certification depends on the context of use, this guideline became necessary as we submit to various Italian Ethics Committees the many clinical studies the DARE project involves. We hope it can help the Ethics Committees to have a more uniform evaluation of these and other similar studies.</p>
Special Issue on 'Computational Modelling in Medicine': Guest editor introduction.
No full textNon disponibil
Supplementary material to Chen 2016 JMBBM
No full textSupplementary material to the paper: "MICRO-CT BASED FINITE ELEMENT MODELS OF CANCELLOUS BONE PREDICT ACCURATELY DISPLACEMENT COMPUTED BY ELASTIC REGISTRATION: A VALIDATION STUDY" by Yuan Chen 1, Enrico Dall'Ara 2, Erika Sales 3, Krishnagoud Manda 3, Robert Wallace 4, Pankaj Pankaj 3, Marco Viceconti 1<div><br></div><div><div>1Department of Mechanical Engineering and INSIGNEO Institute for in silico Medicine, University of Sheffield, UK</div><div>2Department of Human Metabolism and INSIGNEO Institute for in silico Medicine, University of Sheffield, UK</div><div>3Institute for Bioengineering, School of Engineering, The University of Edinburgh, UK</div><div>4Department of Orthopaedics, The University of Edinburgh, UK</div><div><br></div><div>Submitted to Journal of the Mechanical Behavior of Biomedical Materials on September 2015, and in revised form in February 2016.</div><div><br></div><div>Please refer to the paper and to the figure captions for more information.</div><div><br></div></div
Mechanoregulation of bone remodelling in mice under physiological loading
No full textThese are the raw data analysed and reported in the manuscript entitled "EVALUATION OF DIFFERENT BONE REMODELLING THEORIES ON THE CHANGES IN BONE MINERAL DENSITY OF MICE TIBIAE UNDER PHYSIOLOGICAL LOADING" by Yongtao Lu, Enrico Dall’Ara, Maya Boudiffa, and Marco Viceconti, submitted for publication to the Journal of the Royal Society Interface.
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Data for paper "A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population"
No full textComplete results set of the study reported in "A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population" by Pinaki Bhattacharya, Zainab Altai, Muhammad Qasim,
and Marco Viceconti. Biomechanics and Modeling in Mechanobiology (2019) 18: 301. Open-access link: https://doi.org/10.1007/s10237-018-1081-
Pre-operative prediction of soft tissue balancing in knee arthoplasty part 1: effect of surgical parameters during level walking
No full textAn important reason for poor functional outcome of Total Knee Arthroplasty is inadequate soft tissue balancing. Custom-made cutting guides or computer-aided surgical navigation make possible to accurately achieve what is planned; the challenge is to perform a pre-operative planning that properly accounts for soft-tissue balancing. The first step in the development of a patient-specific computer model that can predict during pre-operative planning the post-operative soft-tissue balancing is a better understanding of the role that cutting heights and angles have on the balancing of the soft tissues after TKA as the patient perform the more common daily tasks. In the present study, we conducted a sensitivity analysis of the ligament elongations during level walking due to TKA as a function of position and orientation of the cutting guides, by means of a validated patient-specific dynamic model of the post-TKA knee biomechanics. The results suggest a considerable sensitivity of the collateral ligaments elongation to the surgical variables, and in particular to the varus-valgus angles of both tibia and femur. This complete elongation map can be used as a baseline for the development of reduced-order models to be integrated in pre-operative planning environments. This article is protected by copyright
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