271 research outputs found
“Process for the preparation of 3,6-di-O-acethyl-D-glycals via transacylation and regioselective enzymic hydrolysis”
No full textRegioselective hydrolysis in 6-O position, catalyzed by immobilied lipases . Migration of the acethyl group from 6 to 4 position, givs 3,6-di-O-acethyl-D-glycals in high yields
Procedimento per la preparazione di 3,6-di-O-acetil-D-glicali
No full textidrolisi regioselettiva di glicali per acetilat
D-piranosamine peracetilate 3-monodeprotette e procedimento per la loro preparazione
No full textIdrolisi regioselettiva di piranosamine completamente acetilate, catalizzata da lipasi immobilizzat
“One-pot” synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-α-D-glucopyranose as intermediate for α-D-lactosamine octaacetate preparation
No full textWe have recently reported the synthesis of different acyl pyranoses, bearing only one free
hydroxyl group, obtained by regioselective enzymatic hydrolysis of the peracetylated precursors
and subsequent acyl migration of the hydrolyzed products. As a part of this ongoing research,
we have focused our attention onto the pure regioisomers of 2-acetamido-2-deoxy-1,3,4,6-tetra-
O-acetyl-α-D-glucopyranose (1) as key intermediate for the preparation of a large number of
oligosaccharides. Particularly, we have developed an efficient process to obtain a deprotected
derivative of 1 having only one free hydroxyl group at the C-4 position (3) as a valuable synthon
for the preparation of N-acetyl-α-D-lactosamine heptaacetate (4), building-block in a new
synthetic pathway for oligosaccharides like Sialyl Lewis x. Our chemo-enzymatic strategy allows
to obtain the disaccharide (4) in good overall yield, starting from a commercially available cheap
compound and without any intermediate purification. Our approach is, indeed, an interesting
alternative to the classical multi-step chemical procedures that are often plagued by low yields
and formation of undesired by-products
Sintesi one-pot di 2-acetamido-2-desossi-1,3,6-tri-O-acetil-alfa-D-glucopiranosio per la preparazione di N-acetil-D-lattosamina octaacetato
No full textOne-pot synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-apha-D-glucopyranose as intermediate for the synthesis of N-acetyl-D-lactosamine octaacetate
No full text
"Author Meets Critics: Predrag Cicovacki, Author of Gandhi's Footprints, Meets Critics Sanjay Lal and Carlo Filice"
No full textTwo critics respond to Predrag Cicovacki’s book, Gandi’s Footprints. Cicovacki opens the discussion by presenting his motivations for exploring a paradox, that Gandhi’s work is widely revered but not widely emulated. Cicovacki explores a resolution to the paradox by suggesting how Gandhi’s promising visions may be followed without being imitated, especially Gandhi’s insight that we must seek spiritual grounding for life in a materialistic world. Critic Sanjay Lal affirms Cicovacki’s insight but suggests that precisely because Gandhi’s aspirations for spiritual life were profoundly transformative we should take care not to dilute them into our conventional wisdoms. Critic Carlo Filice asks how Gandhi’s commitment to unified reality could be more clearly articulated once a distinction is drawn between spirit and matter, also how Gandhi’s nonviolence could manage to embrace important exceptions. In reply to critics, Cicovacki proposes an approach to Gandhi informed by the insights of Tagore
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