28 research outputs found
Pedagogia del dono, formazione del cuore, educazione al volontariato: una triade di amore nell’etica della quotidianità
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Expecting an already born child:prospective adoptive parents’ expectations in intercountry adoption
No full textProspective adoptive parents need to develop adequate knowledge of adoptive parenthood and adoptable children before child placement. Pre-adoption preparation has been considered a predictor of positive outcomes both for parents and children, while unrealistic expectations towards adoptive parenthood are related to difficulties in facing the adoptive parenting process, especially those that may arise from the child’s emotional, psychological and behavioural problems. Despite the importance of prospective adoptive parents’ expectations for the positive outcomes of adoption, few studies have examined the expectations of couples awaiting adoption. This article investigates the expectations concerning adoptive parenting in a group of 60 Italian prospective adoptive parents who completed an open-ended questionnaire aimed at understanding their expectations regarding adoptable children and their wishes and fears about adoptive parenting. The thematic analysis highlighted prospective adoptive parents’ expectations of more desirable qualities of children and underestimation of the difficulties they may encounter during the adoptees’ adjustment process. The results offer insights to adoption professionals with a view to enhancing the quality of prospective adoptive parents’ preparation before child placement
Crescere in nuove configurazioni familiari: sfide e risorse dell’affidamento di minori a persone LGBTQ+
No full textDistribution of GD3 in DPPC monolayers: A thermodynamic and atomic force microscopy combined study
No full textGangliosides are the main component of lipid rafts. These microdomains, floating in the outer lea. et of cellular membrane, play a key role in fundamental cellular functions. Little is still known about ganglioside and phospholipid interaction. We studied mixtures of dipalmitoylphosphatidylcholine and GD3 (molar fraction of 0.2, 0.4, 0.6, 0.8) using complementary techniques: 1), thermodynamic properties of the Langmuir-Blodgett films were assessed at the air-water interface (surface tension, surface potential); and 2), three-dimensional morphology of deposited films on mica substrates were imaged by atomic force microscopy. Mixture thermodynamics were consistent with data in the literature. In particular, excess free energy was negative at each molar fraction, thus ruling out GD3 segregation. Atomic force microscopy showed that the height of liquid-condensed domains in deposited films varied with GD3 molar fraction, as compatible with a lipid aggregation model proposed by Maggio. No distinct GD3-rich domain was observed inside the films, suggesting that GD3 molecules gradually mix with dipalmitoylphosphatidylcholine molecules, confirming DeltaG data. Morphological analysis revealed that the shape of liquid-condensed domains is strongly influenced by the amount of GD3, and an interesting stripe-formation phenomenon was observed. These data were combined with the thermodynamic results and interpreted in the light of McConnell's model
A Multicenter Real-Life Study On Anticoagulant Treatment With Direct Oral Anticoagulants In Patients With Ph Negative Myeloproliferative Neoplasms
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Role of Genetic and Acquired Prothrombotic Risk Factors in Genesis of Sudden Sensorineural Hearing Loss.
No full textThe methylenetetrahydrofolate reductase C677T mutation, factor V G1691A (factor V Leiden) mutation, prothrombin G20210A mutation and 8 other laboratory values associated with increased thrombotic risk were analyzed in 40 patients with sudden sensorineural hearing loss (SSHL). The results were compared with those obtained from 120 controls not affected by SSHL. We found a statistically significant higher frequency of hyperhomocysteinemia in the SSHL group compared with controls, and that this was also associated with the presence of homozygosity for the MTHFR C677T mutation. The study results suggest that SSHL might be caused, among other factors, by a combination of these 2 variables. We suggest that this analysis of the MTHFR C677T mutation should be further investigated to establish the etiology of SSHL, and that the same analysis should be taken into account in those patients with high levels of homocysteine
P-glycoprotein inserted in planar bilayers formed from liposomes opened on amorphous carbon Langmuir-Blodgett monolayer
No full textSudden sensorineural hearing loss: A vascular cause? Analysis of prothrombotic risk factor in head and neck.
No full textObjective: This aim of this study was to determine the prevalence of thrombophilic risk factors in sudden sensorineural hearing loss, central retinal vein occlusion, and stroke associated with small vessel disease, with the purpose of investigating and reinforcing the vascular hypothesis in the pathogenesis of sudden sensorineural hearing loss. Design: Case-control study. Genetic and acquired risk factors of these three groups were compared with healthy controls. Study sample: Forty-nine, 60, and 101 patients affected respectively by sudden sensorineural hearing loss, central retinal vein occlusion, or stroke associated with small vessel disease, enrolled during a three-year period were compared with 210 healthy controls. Results: The frequency of hyperhomocysteinemia (homocysteine ≥ 15 μmol/L) was higher in each disease group than in controls. A statically significant, albeit weak, correlation between the MTHFR C677T mutation and hyperhomocysteinemia was found in all three diseases. Conclusions: Hyperhomocysteinemia proved to be a risk factor for sudden sensorineural hearing loss. Based on these results, we propose to analyse homocysteine in sudden sensorineural hearing loss patients and, if its values are high, to evaluate the presence of MTHFR C677T mutation
