1,721,003 research outputs found
Oral appliances for the treatment of obstructive sleep apnea in patients with low C-PAP compliance: A long-term case series
Acute colonic distension in a patient with severe muscular dystrophy receiving non-invasive positive pressure ventilation
Are occlusal features associated with different temporomandibular disorder diagnoses in bruxers?
The Relation Between Daytime Sleepiness and Awake and Sleep Bruxism Report in Patients With Obstructive Sleep Apnoea
Objective: To assess the relationship between daytime sleepiness and both self‐reported awake bruxism (AB) and sleep bruxism (SB) in patients with different severities of obstructive sleep apnoea (OSA). Material and Methods: One hundred and seventy‐four participants (female = 33.9%; mean age [±SD] = 55.1 ± 12.3 years) with polygraphy‐confirmed OSA underwent a self‐reported assessment for both awake and SB and daytime sleepiness, using the BRUX scale questionnaire and Epworth sleepiness scale, respectively. Three BRUX scale sum scores were computed for each patient: total sum score, AB sum score and SB sum score. To assess OSA severity, the apnoea‐hypopnoea index and minimal oxygen saturation (MinSat) were considered. Correlations between daytime sleepiness, BRUX scale scores and OSA severity were assessed using Pearson's test. In addition, a multiple linear regression analysis model was used to assess the predictive effect of both self‐reported awake and SB and OSA severity on daytime sleepiness. Results: A significant, but weak correlation emerged between daytime sleepiness and the BRUX scale total sum score ( r = 0.155; p < 0.05), the awake BRUX scale sum score ( r = 0.174; p < 0.05) and MinSat ( r = 0.194; p < 0.01). No significant correlations were found between OSA severity and any other variables. The multiple linear regression analysis showed that only the awake BRUX scale sum score had a positive predictive association with daytime sleepiness ( B = 0.485; [95% CI = 0.076; 0.936]; p = 0.027). Conclusions: Within the limitations of this study, in individuals with OSA, self‐reported AB showed a predictive effect for daytime sleepiness, while no significant correlation between daytime sleepiness and OSA severity emerged
Effect of a passive exhalation port on tracheostomy ventilation in amyotrophic lateral sclerosis patients: A randomized controlled trial
Botulinum toxin therapy: functional silencing of salivary disorders.
Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and
effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary fistulas that may
have a post-traumatic or post-operative origin. BTX injections can be considered in sialoceles and salivary fistulas after the failure of or
together with conservative treatments (e.g. antibiotics, pressure dressings, or serial aspirations). BTX treatment has a promising role in
chronic sialadenitis. BTX therapy is highly successful in the treatment of gustatory sweating (Frey’s syndrome), and could be considered
the gold standard treatment for this neurological disorder
Botulinum toxin and rehabilitation treatment in inclusion body myositis for severe oropharyngeal dysphagia
Current opinion in diagnosis and treatment of laryngeal carcinoma.
Laryngeal carcinoma is the 11th commonest form of cancer in men world-wide, with 121,000 new cases in 1985. More than 95% of all laryngeal malignancies are squamous cell carcinomas. Treatment indications in cancer of the larynx are often controversial, since there are few comparative studies of different available therapeutic approaches. Surgery and radiotherapy are both widely used, and the choice between these two procedures is the most common therapeutic decision which has to be taken. Laryngeal function preservation has gained more and more weight in the last decades and chemotherapy is also a significant component of several curative approaches. In the last decades, several organ-preserving surgical techniques have become available and consequently total laryngectomy results less applied. Regardless of the treatment modality, Tis, T1, T2 laryngeal carcinomas have an 80-90% probability of cure, whereas for more advanced tumours this is approximately 60%. The most effective approach to laryngeal cancer remains prevention and early diagnosis when this cancer is curable with function preserving treatments
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