1,720,992 research outputs found
[The effect of interleukin 1 and 2 and interferon-gamma on pulmonary edema lesions in mice. I: validation of an experimental model].
No full textStudio sugli effetti delle Interleuchine 1 e 2 e dell'Interferon- gamma sull'edema polmonare lesionale nel topo I:Validazione del modello sperimentale
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The role of hemodynamic monitoring in the diagnosis of a rteriovenous fistulas following penetrating abdominal trauma
No full textVascular injuries after penetrating gunshot wounds can result in arteriovenous fistulas, whose principal anatomical locations are the upper and lower extremities, whereas abdominal vessels are rarely involved. The aim of this paper is to report a case of penetrating abdominal trauma with evidence of visceral damage in which the analysis of hemodynamic data was a useful tool in the early diagnosis of intrarenal and aortocaval fistulas
Clinical features of septic encephalopathy in surgical and trauma patients in the intensive care unit British Journal of Surgery, 83:858, 1996
No full textLa necrosi pancreatica infetta in terapia intensiva
No full textBACKGROUND: Infected necrotizing pancreatitis is the most fulminant variety of this disease. The reported mortality is up to 50%. The haemodynamic features of cardiovascular instability has many similarities to sepsis syndrome, septic shock and multiple organ dysfunction syndrome (MODS). The purpose of this study is to review personal experience in the ICU (hospital of Varese) to determine etiology, treatment and complications. METHODS: Twenty patients treated since 1988 with infected necrotizing pancreatitis required surgical treatment and mechanical ventilation. RESULTS: The mortality rate was 60% and ICU-stay was 26.5 +/- 12.3 days, the median age was 54 +/- 13. Ranson's criteria at admission to the ICU was 6.6 +/- 1.2, Glasgow point was 4.6 +/- 1.2 (5.5 +/- 0.87 died, 3.2 +/- 0.8 survived p < 0.01), Baltazar score 6.2 +/- 2.1 (7.4 +/- 2.1 died, 5.5 +/- 0.9 survived p < 0.05) and SAPS II score 43.4 +/- 12.1 (50.1 +/- 7.8 died, 34 +/- 5.5 survived p < 0.01). The etiology was: gallstones (45%), alcoholism (15%), ERCP (15%) and idiopathic in 25%. Serum pancreatic amylase was 342 +/- 113.9 U/l (550 +/- 100 died, 155 +/- 60 survived p < 0.01), lipase was 334 +/- 176 U/l and transaminases GOT was 123 +/- 46 u/l (156 +/- 90 died, 29 +/- 7 survived p < 0.05). High initial amylase and GOT levels were frequently found in non survived patients. MODS occurred in 17 cases (85%), ARDS in 2 patients (10%), abdominal bleeding in 6 (30%) and septic syndrome in 8 (40%). CONCLUSIONS: It is thus possible that a target-oriented approach including fluid replacement, rapid correction of intestinal underperfusion, inotropic and antibiotic therapy, supply of specific nutrients and other therapeutic strategies as open laparostomy must be employed to prevent MODS or septic syndrome in pancreatic infection after acute necrotizing pancreatitis
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