1,721,176 research outputs found
International gestational age-specific centiles for umbilical artery Doppler indices: a longitudinal prospective cohort study of the INTERGROWTH-21st Project
Effects of coronavirus 19 pandemic on maternal anxiety during pregnancy: a prospectic observational study
EP31.11: Time to diagnosis type IV sacrococcygeal teratoma: a case report and review of literature
The combined use of ultrasound with magnetic resonance in the study of fetal brain: From the diagnosis towards the prognosis and beyond!
EP19.12: A national survey on current practice of ultrasound in the management of postpartum hemorrhage
Concomitant effects of late fetal growth restriction and intra-cytoplasmatic sperm injection on fetal cardiac remodelling: a case report
Perinatal assessment of lung hemodynamics. A new tool for predicting of bronchopulmonary dysplasia
Administration of antenatal corticosteroid is associated with reduced fetal growth velocity: a longitudinal study
Objective: To elucidate whether antenatal administration of corticosteroids in pregnancies with threatened preterm labor affects growth velocity. Methods: A cohort of 262 pregnancies exposed to antenatal corticosteroids longitudinally studied and delivered from 36 weeks (cases) were compared to an unexposed group of 270 women (controls). Methods: Fetal growth was assessed analyzing the growth velocity of head circumference (HC), abdominal circumference (AC), femur length (FL) and estimated fetal weight (EFW). Growth velocity (GV) was calculated as the difference in the Z-score between the biometric measurements recorded at the time of steroids administration and at 36 week of gestation, divided by the time interval (expressed in days) between the two scans and multiplied by 100. Similarly, changes in the Pulsatility Index (PI) of uterine, umbilical (UA), middle cerebral (MCA) arteries and cerebroplacental ratio (CPR) during the same time interval were also computed. Results: Median gestational age at steroid administration (30.2 weeks vs 30.4) and follow-up ultrasound (36.4 weeks vs 36.4) were similar between cases and controls. In pregnancies exposed to antenatal corticosteroids, growth velocity in the HC (−0.61 vs. 0.12; p ≤ 0.001), AC (−0.55 vs. −0.04; p ≤ 0.001) and EFW (−0.89 vs. 0.06; p ≤ 0.001) were lower when compared to pregnancies not exposed to steroid therapy, while there was no difference in the growth velocity of FL (−0.05 vs 0.19; p =.06) or in any of the Doppler parameters explored. Conclusion: In pregnancies exposed to antenatal steroid therapy, there is a significant reduction in fetal growth velocity not otherwise associated with changes in cerebroplacental Dopplers
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