165 research outputs found
Syntheses of 4-[(1H,3H)-pyrimidine-2,4-dion-1-yl]- and 4-[(1H,3H)-5- methylpyrimidine-2,4-dion-1-yl]-1,6-heptadienes
No full textHeptadienes containing nucleic bases are attractive building blocks for the synthesis of carbocyclic oligonucleotide analogs. Herein, we report an alternative synthetic route to 4-[(1H,3H)-pyrimidine-2,4-dion-1-yl]-1,6- heptadiene and 4-[(1H,3H)-5-methylpyrimidine-2,4-dion-1-yl]-1,6-heptadiene via building the pyrimidine ring utilizing 4-isocyanato-1,6-heptadiene intermediate.CROXALL WJ, 1950, J AM CHEM SOC, V72, P803, DOI 10.1021-ja01158a040; CZARNIK AW, 1981, J ORG CHEM, V46, P815, DOI 10.1021-jo00317a037; HWU JR, 1995, J ORG CHEM, V60, P856, DOI 10.1021-jo00109a016; ISRAEL M, 1973, J MED CHEM, V16, P1, DOI 10.1021-jm00259a001; NAIM A, 1992, TETRAHEDRON LETT, V33, P6779, DOI 10.1016-S0040-4039(00)61774-4; NAIM A, 1990, SYNTHETIC COMMUN, V20, P3439, DOI 10.1080-00397919008051586; SEMMELHA.MF, 1973, J AM CHEM SOC, V95, P7325, DOI 10.1021-ja00803a021; Tsai JY, 2003, J ORG CHEM, V68, P1235, DOI 10.1021-jo026379k11111
Manipulate energy transport via fluorinated spacers towards record-efficiency 2D Dion-Jacobson CsPbI<sub>3</sub> solar cells
No full textTwo-dimensional (2D) Dion-Jacobson (D-J)-type cesium lead iodide CsPbI 3 perform remarkably in terms of stability. However, the complex interactions between spacer and inorganic layers limit its excellent progress in perovskite solar cells (PSCs). Herein, starting from the considerable structural diversity of organic spacers, we engineer 2D CsPbI 3 with fine-tuning functionalities. Specifically, for the first time we embedded fluorinated aromatic cations in 2D D-J CsPbI 3, and successfully applied it into construction of high-performance PSCs. Compared with constitutive 1,4-diaminobenzene (PDA), the fluorinated 2-fluorobenzene-1,4-diamine (F-PDA) component greatly expands the dipole moment from 0.59D to 3.47D, which reduces the exciton binding energy of the system. A theoretical study shows that the spacer layer and inorganic plane are more enriched with charge accumulation in (F-PDA)Cs n– 1Pb nI 3 n+ 1. The results show that (F-PDA)Cs n– 1Pb nI 3 n+ 1 demonstrates more significant charge transfer between organic and inorganic layers than (PDA)Cs n– 1Pb nI 3 n+ 1, and it is confirmed in the femtosecond transient absorption experiment. Moreover, the interactions of the fluorinated spacer with the [PbI 6] 4 – plane effectively manipulate the crystallization quality, and thus the ion migration and defect formation of target 2D CsPbI 3 are inhibited. As a result, we obtained a record power conversion efficiency (PCE) beyond 15% for 2D D-J (F-PDA)Cs 3Pb 4I 13 (n = 4) PSCs with significantly improved environmental stability compared with the three-dimensional (3D) counterparts. Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Photovoltaic Materials and Device
A letter to Dion, [electronic resource] : Occasion'd by his Book call'd Alciphron, or The Minute Philosopher. By the Author of the Fable of the Bees.
No full textDion = George Berkeley, Bishop of Cloyne.Author of the fable of the bees = Bernard de Mandeville.In some copies sig. A2 is unsigned.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
Déconvenues diplomatiques et philologiques de Fabricius. Les rapports de Rome avec les peuples et cités d'Italie entre 285 et 280 av. J.-C. à la lumière d'un fragment de Dion Cassius
No full textGhislaine Stouder, Fabricius' diplomatie and philological disappointment. Rome's relationship with the peoples and cities of Italy between 285 and 280 B.C., in the light of a fragment of Cassius Dio, DHA 33/1, 2007, 47-70.
Abstract: Starting from a fragment by Cassius Dio (fg. 39.1), the author takes into account an embassy disregarded by the modern historians of Roman diplomacy, that of Fabricius which the successive editors have situated in 283 B.C. The notice is reappraised in the light of the conflicts involving Rome against the Gauls, the Etruscans and the Umbrians together with the preparation for war in South Italy, in Tarentum. Thus the reexamination of the transmission and historical context of the fragment makes it possible to establish a new chronology of the event - now dated 285/4 B.C. The study also reconsiders Cassius Dio's contribution to the story of that period and enables one to appreciate his unique testimony on the outbreak of the Tarentine war.Ghislaine Stouder, Déconvenues diplomatiques et philologiques de Fabricius. Les rapports de Rome avec les peuples et cités d'Italie entre 285 et 280 av. J.-C. à la lumière d'un fragment de Dion Cassius, DHA 33/1, 2007, 47-70.
Résumé : Partant d'un fragment de Dion Cassius (fg. 39.1), l'auteur s'est attaché à l'étude d'une ambassade négligée dans l'histoire de la diplomatie romaine, celle de Fabricius que les éditeurs successifs ont datée de 283 av. J.-C. La notice est réappréciée à la lumière des conflits impliquant Rome contre les Gaulois, les Étrusques et les Ombriens, parallèlement aux préparatifs de guerre en Italie du Sud, à Tarente. Le réexamen de la transmission et du contexte historique du fragment permet ainsi d'aboutir à une chronologie nouvelle de l'épisode, désormais daté de 285/4 av. J.-C. Letude revient aussi sur l'apport pendant longtemps trop souvent négligé de Dion Cassius pour cette période de l'histoire romaine et permet d'apprécier son témoignage unique sur le déclenchement de la guerre contre Tarente.Stouder Ghislaine. Déconvenues diplomatiques et philologiques de Fabricius. Les rapports de Rome avec les peuples et cités d'Italie entre 285 et 280 av. J.-C. à la lumière d'un fragment de Dion Cassius. In: Dialogues d'histoire ancienne, vol. 33, n°1, 2007. pp. 47-70
A complex and punctate distribution of three eukaryotic genes derived by lateral gene transfer
No full textAbstract Background Lateral gene transfer is increasingly invoked to explain phylogenetic results that conflict with our understanding of organismal relationships. In eukaryotes, the most common observation interpreted in this way is the appearance of a bacterial gene (one that is not clearly derived from the mitochondrion or plastid) in a eukaryotic nuclear genome. Ideally such an observation would involve a single eukaryote or a small group of related eukaryotes encoding a gene from a specific bacterial lineage. Results Here we show that several apparently simple cases of lateral transfer are actually more complex than they originally appeared: in these instances we find that two or more distantly related eukaryotic groups share the same bacterial gene, resulting in a punctate distribution. Specifically, we describe phylogenies of three core carbon metabolic enzymes: transketolase, glyceraldehyde-3-phosphate dehydrogenase and ribulose-5-phosphate-3-epimerase. Phylogenetic trees of each of these enzymes includes a strongly-supported clade consisting of several eukaryotes that are distantly related at the organismal level, but whose enzymes are apparently all derived from the same lateral transfer. With less sampling any one of these examples would appear to be a simple case of bacterium-to-eukaryote lateral transfer; taken together, their evolutionary histories cannot be so simple. The distributions of these genes may represent ancient paralogy events or genes that have been transferred from bacteria to an ancient ancestor of the eukaryotes that retain them. They may alternatively have been transferred laterally from a bacterium to a single eukaryotic lineage and subsequently transferred between distantly related eukaryotes. Conclusion Determining how complex the distribution of a transferred gene is depends on the sampling available. These results show that seemingly simple cases may be revealed to be more complex with greater sampling, suggesting many bacterial genes found in eukaryotic genomes may have a punctate distribution.</p
[[alternative]]Studies on the Constituents of Ganoderma Comphoratum
No full text[[abstract]]Ganoderma comphoratum Zang et Su, SP. nov., growing rarely on the inner cavity wall of Cinnamomum comphora (L) Prcsl. in Taiwan, is a new genus of Ganoderma species. The methanolic extract of the fruiting body of the ganoderma comphoratum is separated by column chromatography, normal phase high performance liquid chromatography. As a result, thirteen compounds were isolated and identified by the spectral analysis. These Compounds are:
＊Compound A：4α-Methylergost-8, 24 (28)-dien-3, 11-dion-26-oic acid.
Compound B：4α-Methylergost-8, 24 (28)-dien-3, 7, 11-trion -26-oic acid.
＊Compound C：7β-Hydroxy-4a-methylergost-8, 24(28)-dien-3, 11-dion-26-oic acid.
Compound D：7β-Hydroxy-4a-methylergost-8, 24(28)-dien-3, 7, 11-trion-26-oic acid.
＊Compound E：4α-Methylergost-8, 14, 24 (28)-trien-3, 11-dion-26-oic acid.
＊Compound F：7β-Hydroxy-4α-methylergost-8, 14, 24(28)-trien-3, 11-dion-26-oic acid.
＊Compound G：Methyl-3α, 2α-dihydroxy-4α-methylergost-8, 24(28)-dien-7, 11-dion-26-oate.
＊Compound H：2, 2', 5, 5' -tetramethoxy-3, 4, 3', 4'-di-methylenedioxy-6, 6'-dimethyl biphenyl.
Compound I：3β-Hydroxy-24-methylenelanost-7, 9(11)-dien-21-oic acid.
Compound J：3β, 15α-Dihydroxy-24-methylenelanost-7, 9(11)-dien-21-oic acid.
Compound K：24-Methylenedihydrolanosterol.
Compound L：9(E)-Octadecenoic acid.
Compound M：9, 12(E, E)-Octadecadienoic acid.
There were six new compounds (＊ symbol) which haven't reported on any paper.
Erratum: Bioelectronic neural pixel: Chemical stimulation and electrical sensing at the same site (Proceedings of the National Academy of Sciences of the United States of America (2016) 113: 34 (9440-9445) DOI: 10.1073/pnas.1604231113)
No full textCorrection for "Bioelectronic neural pixel: Chemical stimulation and electrical sensing at the same site," by Amanda Jonsson, Sahika Inal, llke Uguz, Adam J. Williamson, Loïg Kergoat, Jonathan Rivnay, Dion Khodagholy, Magnus Berggren, Christophe Bernard, George G. Malliaras, and Daniel T. Simon, which appeared in issue 34, August 23, 2016, of Proc Natl Acad Sci USA (113:9440-9445; first published August 9, 2016; 10.1073/pnas.1604231113). The authors note that, due to a printer's error, the first name of the third author, Ilke Uguz, originally published with the first letter as a lowercase letter l. This letter should instead appear as an uppercase letter i. The online version has been corrected
Holy or wholly? : a systematic theological study of Sabbath keeping in the works of Samuele Bacchiocchi and Marva J. Dawn
No full textThesis (MTh)--Stellenbosch University, 2018.ENGLISH ABSTRACT: This thesis is a study of the doctrinal concept of Sabbath keeping in the works of Samuele Bacchiocchi and Marva J. Dawn, respectively. Bacchiocchi is from the Seventh Day Adventist
(SDA) Church which believes that the seventh day of the week is to be kept as the Sabbath. On the other hand, Marva Dawn is a Lutheran who believes in the relevance and benefits of keeping one day in a week as the Sabbath. Using a qualitative content analysis of books and articles by these two Theologians the doctrinal concept of Sabbath keeping is extensively
studied in their respective works to find the distinctive theological contributions to Sabbath keeping that each author offers. In addition, other theologians including those who have written on Sabbath keeping are cited as secondary sources to maximize the critical theological discourse and outcome of this study. The intention of this process is to facilitate a critical
engagement on Sabbath keeping in the works of Bacchiocchi and Dawn to gain a new, more complex, and nuanced understandings of Sabbath keeping. The study is then concluded by summarising the findings of the research, how the theology of Sabbath keeping can be enriched, developed, nuanced, and problematized through this critical theological engagement
between the works of Samuele Bacchiocchi and Marva J. Dawn, and suggesting areas for future research.AFRIKAANSE OPSOMMING: Hierdie tesis is ʼn studie van die leerstellinge oor Sabbats onderhoud in die werke van Samuele Bacchiocchi en Marva J. Dawn onderskeidelik. Bacchiocchi werk van die perspektief van die Sewende Daagse Adventiste Kerk (SDA) wat glo dat die sewende dag as die Sabbat onderhou
moet word. Marva J. Dawn, aan die ander kant, is ʼn Lutheraan wat die tradisie verteenwoordig
wat die relevansie en voordele uitwys om een dag in die week as Sabbat te onderhou. Deur gebruik te maak van kwalitatiewe inhoud analise van boeke en artikels deur hierdie twee teoloë, is die leerstellinge en dogma van Sabbat onderhoud in diepte bestudeer in die onderskeie werke om sodoende ʼn kenmerkende bydrae na Sabbats onderhoud te bevorder deur ook beide teoloë se bydrae te respekteer. Bykomend word ander teoloë wat bydraes maak oor Sabbats onderhoud as sekondêre bronne aangehaal om sodoende kritiese teologiese diskoers en uitkomste te maksimaliseer. Die intensie van die proses is om ʼn kritiese interaksie oor Sabbat onderhoud in die werke van Bacchiocchi en Dawn te fasiliteer om sodoende nuwe, meer
komplekse en genuanseerde verstaan van Sabbat onderhoud te ontwikkel. Die studie se gevolgtrekking gaan opsommend om met die bevindinge en meer spesifiek hoe die teologie van Sabbat onderhoud verdiep, meer ontwikkeld en genuanseerd kan wees deur kritiese teologiese interaksie met die werke van Samuele Bacchiocchi en Marva J. Dawn. Daar word
ook voorstelle gemaak vir toekomstige navorsing in hierdie veld
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