1,721,191 research outputs found
Atlas of SPECT-CT
The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gauned wudespread acceptance in many clinical settings, especially within incology, and now SPECT-CT promises to emulate its success. Useful applications of this new approach have been identified not only in oncology but also andocrinology, cardiology, internal medicine and other specialities. This atlas, which includes hundreds of high-quality images, is a user-frinendly guide to the optimal use and interpretation of SPECT-CT. The full range of potential SPCET-CT applications in clinical routine is considered and assesed by acknowledged experts. The book is designed to serve a reference text for both nuclear physicians and radiologists; it will also provide fundamental support for radiographers, technologists, and nuclear medicine and radiology residents. Following the editors' other atlases on PET-CT and non-FDG PET-CT, the "Atlas of SPECT-CT" completes a triology offering up-to-date information and guidance on the full spectrum of hybrid imaging
PET-CT Beyond FDG
Althoug [18F]fluorodeooxyglucose (FDG) generally shows an exellent performance as a cancer-imaging agent when using PET/CT, there are some settings in wich other radiopharmaceuticals offer advantages. Such non-FDG tracers are now gaining widespread acceptance not only research but also in clinical practise, with the acquisition of promising results in the management of various cancers. This atlas, including about 500 highquality images, is a user-friendly guide to PET/CT imaging beyond FDG. A wide range of tracers is covered such as 18F- and 11C-choline, 11C-methionine, 18F-ethyl-L-tyrosine, 68Ga-DOTA-NOC, 11C-acetate, 11C-thymidine and 18F-DOPA. Troughout, the emphasis is on image interpretation with guidance on the recognition of normal, begin, and malignant uptake and clear instruction on learning points and pitfalls. This book is a companion to the editors' recently published Atlas of PET/CT, which focuses exclusively on the use of FDG. It is designed to serve as a reference text for both nuclear physicians and radiologists, and will also be of great benefit to radiographers, tschnologists and nuclear medicine and radiology residents
Atlas of PET-CT. A quick guide to image interpretetion
This user-friendly atlas, featuring about 500 images, should be a quick guide to interpreting PET/CT images with FDG in oncology. It also illustrates how to recognize normal, para physiological, and begin pathological upatakes in a case-based pratical manner. The text, wich includes most relevant technical and pathophysiological premises, covers the main clinical applications and clearly articulates learning points and pitfalls. This atlas aims to become a standard text for nuclear menicine physicians and radiologists, residents and technicians whose work involves in PET/Ct imaging. This book is also suiteable for both unadergarduate and post graduate courses
How can we optimize modem imaging techniques for breast cancer, with main reference to breast recurrence?
Medicina Nucleare. TECNICHE - METODOLOGIE - APPLICAZIONI per studenti e medici di medicina generale
Detection of a-to-i rna editing in sars-cov-2
ADAR1-mediated deamination of adenosines in long double-stranded RNAs plays an important role in modulating the innate immune response. However, recent investigations based on metatranscriptomic samples of COVID-19 patients and SARS-COV-2-infected Vero cells have recovered contrasting findings. Using RNAseq data from time course experiments of infected human cell lines and transcriptome data from Vero cells and clinical samples, we prove that A-to-G changes observed in SARS-COV-2 genomes represent genuine RNA editing events, likely mediated by ADAR1. While the A-to-I editing rate is generally low, changes are distributed along the entire viral genome, are overrepresented in exonic regions, and are (in the majority of cases) nonsynonymous. The impact of RNA editing on virus–host interactions could be relevant to identify potential targets for therapeutic interventions
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