429 research outputs found
Role of CRP in COVID-19 pneumonia: A single-center experience of 1000 cases in a tertiary care setting in India
No full textIntroduction
Robust data are available for C-reactive protein (CRP) in bacterial infection, and it can be used in this coronavirus disease 2019 (COVID-19) pneumonia pandemic for initial assessment before planning of treatment in indoor settings in comparison with other inflammatory markers and computed tomography (CT) severity.
Materials and methods
A prospective, observational, follow up study was conducted that included 1000 COVID 19 cases confirmed with RT PCR. All cases were assessed with lung involvement documented and categorized based on high resolution computed tomography (HRCT) thorax, oxygen saturation, and inflammatory markers such as CRP at the entry point and follow up. Age, sex, comorbidities, use of BIPAP/NIV (Bi-level positive airway pressure/Non-invasive ventilation), and outcomes such as with or without lung fibrosis as per HRCT severity were key observations. Statistical analysis was done using χ2 test.
Results
Age (50 years) and sex (male versus female) had a significant association with CRP in predicting severity (P < 0.00001 and P < 0.010, respectively). CT severity score at the entry point with CRP level had a significant correlation (P < 0.00001). CRP level had a significant association with duration of illness (P < 0.00001). Comorbidities had a significant association with CRP level (P < 0.00001). CRP level had a significant association with oxygen saturation (P < 0.00001). BIPAP/NIV requirement during hospitalization had a significant association with CRP level (P < 0.00001). Timing of BIPAP/NIV requirement had a significant association with CRP level. (P < 0.00001). Follow-up CRP titer during hospitalization as compared with the entry point normal and abnormal CRP levels showed a significant association in post-COVID lung fibrosis (P < 0.00001).
Conclusion
CRP is an easily available and universally acceptable inflammatory marker and documented to play a very crucial role in predicting timings of interventions and post-COVID lung fibrosis
Disproportionate tachycardia and tachypnea in pulmonary tuberculosis: A marker of concurrent cardiac dysfunction
No full textCardiovascular involvement in tuberculosis is not uncommon. Cardiac dysfunction is a clinical presentation due to direct or indirect affection due to tuberculosis. Cardiac dysfunction is possible without structural cardiac disease. In this case report, a 32-year-old male presented with constitutional symptoms for 6 months with acute deterioration with tachycardia and tachypnea with hypoxia 2 weeks before hospitalization. Radiological investigations documented conglomerated miliary tuberculosis and confirmed by sputum smear microscopy and Gene Xpert MTB/Rif. Cardiac investigations revealed sinus tachycardia in electrocardiogram, raised cardiac enzymes in laboratory evaluation, and “global left ventricular hypokinesia” with reduced ejection fraction in echocardiography. We have started Anti-tuberculosis treatment as per National guidelines for 6 months with steroids backup for four weeks. We have documented cardiac function improvement in one month post treatment, bacteriological cure after 2 months of ATT and near complete radiological resolution after 6 months. We recommend cardiac workup in all pulmonary tuberculosis cases with disproportionate tachycardia and tachypnea with or without hypoxia
Computerised library system and the legal profession
No full textThe author explores the computer applications and computerised methods of functioning that have become prevalent in India both in the library system and in the legal profession in India. However, Patil argues that modern technology and managerial techniques evolved during the last few years in India are no substitute for a capable and efficient administrator, who could use these tools to achieve the goals set for law libraries and to the legal profession. The prospects of introducing modern technology in India depends on administrative, physical, and operational decisions. Further, such a system finally created with its infrastructure, may give lead for the establishment of world-wide information network activities. (Editor’s abstract.
The Benefits of Being Economics Professor A (and not Z)
No full textAlphabetic name ordering on multi-authored academic papers, which is the convention in the economics discipline and various other disciplines, is to the advantage of people whose last name initials are placed early in the alphabet. As it turns out, Professor A, who has been a first author more often than Professor Z, will have published more articles and experienced afaster growth rate over the course of her career as a result of reputation and visibility. Moreover, authors know that name ordering matters and indeed take ordering seriously: Several characteristics of an author group composition determine the decision to deviate from the default alphabetic name order to a significant extent.performance measurement, incentives, economists, name ordering
Elements of Ethnotaxonomy in Dhule and Nandurbar Districts (Maharashtra)
No full textDhule and Nandurbar districts of Maharashtra are mainly inhabited by tribals and rural folks. The author’s ethnobotanical and floristic forays in these districts brought out certain elements of ethnotaxonomy like ethnotaxonomic markers, classifications, principles of nomenclature and exomorphic features. The facts gathered indicated that the people in the area are fairly flooded with reckonable elements of ethnotaxonomy. And 22 ethnotaxonomic markers are identified. These are evaluated and discussed pertinently in this paper.-----------------------------------------------------------------------------------------------------Post Graduate Department of Botany, S.S.V.P.S’s L.K. P.R.Ghogrey Science College, Dhule-424005 (Maharashtra), India*Corresponding author, Email: [email protected] Cite This Article As: D.A. Patil. 2010. Elements of Ethnotaxonomy in Dhule and Nandurbar Districts (Maharashtra). J. Ecobiotechnol. 2(3): 18-25
Trends of chronic obstructive pulmonary disease diagnosis and treatment in rural setting in India: A large, two-center, prospective, observational study of 6000 cases in tertiary care setting in India
No full textBackground: Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality due to chronic respiratory illness in India. More than half of COPD patients were not getting adequate rationale inhalation treatment in primary to tertiary care setting. Materials and Methods: A prospective, observational, interview (questionnaire)-based complete workup COPD study conducted during June 2016 to June 2019 in the Department of Pulmonary Medicine, Venkatesh Chest Hospital, and MIMSR Medical College, Latur, screened 12,000 cases with chronic respiratory symptoms with cough, sputum production, and shortness of breath, and all cases were undergone spirometry and 6000 COPD cases were enrolled. In this study, we assessed disease knowledge and the methods of treatment offered to all patients before enrollment by applying questionnaire. Statistical analysis was done using single proportion test (Chi-square test). Observation and Analysis: We have observed that 3% of study cases were aware of their illness “COPD disease,” 54% are not knowing the disease or not counseled for COPD disease ever before, and 43% are not convinced as they are having COPD (categorized as “difficult patient”) (P < 0.0001). Inhalation treatment was offered in only 58% of COPD cases, levosalbutamol monotherapy in 31% of cases, levosalbutamol plus beclometasone in 18% of cases, and formoterol plus budesonide or salmeterol plus fluticasone only in 9% of COPD cases (P < 0.0001), latter being categorized as “difficult treatment” being costlier than former ones. We also observed irrational and exuberant use of oral medicines in 42% of COPD cases, theophylline in 16%, salbutamol in 7%, and oral steroids in 19%, and these medicines were preferred by treating doctors over inhalation treatment in spite of knowledge of inhalation treatment and categorized as “difficult doctor” (P < 0.0001). Conclusion: COPD is less efficiently evaluated and halfheartedly treated in rural setting, and more emphasis should be given to spirometry training for proper diagnosis and awareness regarding advantages of inhalation treatment over oral medicines
Influence of geometric parameters on 3D periodic lattice effective properties
No full textLattice materials are generated by tessellating a unit cell, composed of a specific truss configurations, in an infinite periodicity to combine the effect of bulk material properties and geometric periodicity. They offer enhanced mechanical and dynamic properties per unit mass, and the ability to engineer the material response by optimizing the unit cell. Characterizing lattice properties through experiments can be a time consuming and costly process, so analytical and numerical methods are crucial. Specifically, the Bloch-wave homogenization approach allows one to characterize the effective static properties of the lattice unit cell while simultaneously analyzing wave propagation properties. While this analysis has been used for some time, a thorough study of this approach on 3D lattice materials with different symmetries and geometries is presented here. Using Bloch-wave homogenization, multiple periodic lattices with cubic, transversely isotropic, and tetragonal symmetry, including an auxetic geometry, over a wide range of relative densities are analyzed within a finite element framework. The effect of geometric parameters on lattice properties is discussed and a comparison between lattices based on their anisotropy index is presented. Method studied in this thesis can be extended for designing multifunctional metamaterials with optimized static and dynamic properties simultaneously. This work can also serve as the basis for nondestructive evaluation of metamaterials properties using ultrasonic velocity measurements.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-05-01The student, Ganesh Patil, accepted the attached license on 2019-04-24 at 19:00.The student, Ganesh Patil, submitted this Thesis for approval on 2019-04-24 at 19:11.This Thesis was approved for publication on 2019-04-25 at 12:03.DSpace SAF Submission Ingestion Package generated from Vireo submission #13897 on 2019-08-22 at 15:08:33Made available in DSpace on 2019-08-23T20:36:11Z (GMT). No. of bitstreams: 2
PATIL-THESIS-2019.pdf: 3995937 bytes, checksum: 253c02515a72bc6ca31f3c9efedf6314 (MD5)
LICENSE.txt: 4209 bytes, checksum: 6c4ad2393972f2d5134133cccf2e87e4 (MD5)
Previous issue date: 2019-04-25Embargo set by: Seth Robbins for item 112211
Lift date: 2021-08-23T20:36:18Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112211 on 2021-08-24T09:15:10Z
One Minute Preceptor Model – place or to replace
No full textIntroduction: Neher\u27s 1992 One Minute Preceptor Model (OMP) offers a concise teaching approach based on five micro skills. Its acceptance led to research on efficacy, with a critical factor being the teacher\u27s skill. In medical education, where small group teaching prevails, understanding factors influencing teaching effectiveness is crucial. Methods: Conducted at Dr. D Y Patil Medical College, the mixed-methods interventional study involved 32 Postgraduate Students and 4 Professors. A randomized controlled trial and qualitative interviews assessed the impact of OMP on teaching efficacy and gathered teachers\u27 experiences. Results: Quantitative analysis revealed varied preferences among teachers for OMP and traditional methods, emphasizing the importance of teacher choice. Thematic analysis of qualitative interviews highlighted perceptions favouring OMP for efficiency and traditional methods for foundational teaching. Conclusion: An approach, to accommodate different teaching preferences, can enhance overall educational outcomes
Recommended from our members
Additive Manufacturing of AZ31B Magnesium Alloy via Friction Stir Deposition
No full textAdditive friction stir deposition (AFSD) of AZ31B magnesium alloy was conducted to examine evolution of grain structure, phases, and crystallographic texture. AFSD was carried out using a hollow tool made from tool steel at a constant rotational velocity of 400 rpm on the AZ31B base plate. Bar stock of AZ31B was utilized as a feed material. The linear velocity of the tool was varied in the range of 4.2-6.3 mm/s. The feed rate of the material had to be maintained at a half value compared to the corresponding linear velocity for the successful deposition. The layer thickness and length of the deposits were kept constant at 1 mm and 50 mm respectively. The tool torque and actuator force values were recorded during the process and for calculation of the average input energy for each processing condition. Temperature during the AFSD experiments was monitored using a type k thermocouple located 4 mm beneath the deposition surface at the center of the deposition track. The average input energy values showed a decreasing trend with increasing tool linear velocity. The temperature values during deposition were ∼0.7 times the liquidus of the alloy. The deposited material then was examined by laser microscope and profilometer, X-ray diffraction, scanning electron microscopy, electron back scatter diffraction (EBSC), contact angle measurement and micro hardness tests. The AFSD AZ31B samples showed reduction in areal surface roughness with an increase in the tool linear velocity. The X-ray spectra revealed increase in the intensity of prismatic planes of α-Mg phase with increase in tool linear velocity. AFSD of AZ31B Mg alloy resulted in shifting of the grain size from a broader and courser distribution within the feed material to a tighter distribution. Moreover, EBSD observations confirmed the refinement in grain size distribution as well as the presence of predominantly prismatic texture for the AFSD samples when compared to the feed material. There was a marginal improvement in the hardness for the AFSD samples compared to the feed material. However, there was no significant change in the contact angle measurements in simulated body fluid for the AFSD samples compared to the feed material. The current work demonstrated ability of AFSD technique for the additive fabrication of magnesium-based alloys and provided a methodology for examining various process attributes influencing the processing-structure-property relationship
DESIGN AND PROCESS OPTIMIZATION OF ORAL FLOATING DRUG DELIVERY SYSTEM OF AMOXICILLIN TRIHYDRATE
No full text- …
