40 research outputs found
Solar powered charge stations for electric vehicles
No full textEvery hour, the sun emits more energy onto the Earth’s surface than our entire world population uses in one year. [1] Solar power provides us with the possibility of a cleaner and more renewable future. Global climate change as a result of greenhouse gases and the effects of low air quality caused by pollutants have become very substantial issues in our world today. The costs associated with greenhouse gas and air pollutant emissions, and the effect they have on human lives and human health, are major and growing concerns. The development and installation of solar powered charging stations will reduce the amount of greenhouse gases emitted into the atmosphere, future costs associated with climate change, and health issues. Thus, there is environmental, social, and economic value associated with the installation of solar powered charge stations. Solar powered charging stations have the potential of significantly reducing air pollutants and improving urban air quality. The electrification of transportation and the use of solar powered charging stations as an electricity source will improve people’s quality of life
Microcystic Lymphatic Malformation (Lymphangioma Circumscriptum) Treated Using a Minimally Invasive Technique of Radiofrequency Ablation and Sclerotherapy
No full textDistance to specialist medical care and diagnosis of obstructive sleep apnea in rural Saskatchewan
No full textMonitoring the Effect of Storage Time and Temperature on Serum Clinical Biochemistry Analytes
No full textTinea capitis in the form of concentric rings in an HIV positive adult on antiretroviral treatment
No full textDermatophyte infection may present in the form of concentric rings caused by Trichophyton concentricum, known as Tinea Imbricata. In immunosuppressed patients, there are reports of lesions in the form of concentric rings caused by dermatophytes other than Trichophyton concentricum too, mostly by Trichophyton tonsurans, known as Tinea indesiciva or Tinea pseudoimbricata. We report a case of tinea capitis in a HIV-positive adult woman on antiretroviral therapy, who presented with concentric rings of papules and pustules with slight scaling on the scalp along with diffuse thinning of hair. Both Potassium hydroxide mount and culture showed the presence of Dermatophytes. Tinea capitis is considered rare in adults, but new cases are being reported in immunocompromised as well as in immunocompetent patients. The pertinent features of this case are: HIV-positive adult female on antiretroviral therapy, presenting with tinea capitis in the form of concentric rings; culture from the lesion grew Microsporum audouinii; responding to oral Terbinafine
Lethal midline granuloma
No full textLethal midline granuloma is a relatively rare disease characterized by destruction and mutilation of the nose and other structures of respiratory passages. The nonspecificity of symptoms obscures the correct diagnosis and is responsible for the delay in treatment which can be detrimental as this grave disease calls for urgent intervention. We present a case report of this disease in a 35 year old male who gave a short two month history of the clinical symptoms
Fast identification of biological pathways associated with a quantitative trait using group lasso with overlaps.
No full textWhere causal SNPs (single nucleotide polymorphisms) tend to accumulate within biological pathways, the incorporation of prior pathways information into a statistical model is expected to increase the power to detect true associations in a genetic association study. Most existing pathways-based methods rely on marginal SNP statistics and do not fully exploit the dependence patterns among SNPs within pathways.We use a sparse regression model, with SNPs grouped into pathways, to identify causal pathways associated with a quantitative trait. Notable features of our "pathways group lasso with adaptive weights" (P-GLAW) algorithm include the incorporation of all pathways in a single regression model, an adaptive pathway weighting procedure that accounts for factors biasing pathway selection, and the use of a bootstrap sampling procedure for the ranking of important pathways. P-GLAW takes account of the presence of overlapping pathways and uses a novel combination of techniques to optimise model estimation, making it fast to run, even on whole genome datasets.In a comparison study with an alternative pathways method based on univariate SNP statistics, our method demonstrates high sensitivity and specificity for the detection of important pathways, showing the greatest relative gains in performance where marginal SNP effect sizes are small
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Assessing Sustainability of E-Commerce Goods Distribution
No full textThe growth of e-commerce, spurred by the internet, has transformed urban goods flow. What would previously have been a trip to a store is now a hassle-free delivery to the home. With consolidated and optimized delivery tours, e-commerce has the potential to make urban goods flow economically viable, environmentally efficient, and socially equitable. However, as e-retailers compete with increasingly consumer-focused service, urban freight witnesses a significant increase in associated distribution costs and negative externalities including greenhouse gas emissions advancing global climate change, as well as criteria pollutant emissions worsening local air quality and thus affecting those living close to logistics clusters. Thus, considering the potential of e-commerce to render economically viable, environmentally efficient, and socially equitable urban goods flow, it is pertinent to understand the opportunities and challenges associated with urban freight in light of the increasingly consumer-focused e-commerce distribution. To this end, the author develops A) the impact of e-commerce on urban goods distribution, with a simulation framework founded on consumer shopping behavior simulating urban goods flow, B) the impact of key delivery environment parameters on e-commerce goods distribution, with a continuous approximation (CA) framework modeling last-mile distribution operation for an e-retailer, and C) the impact of demand uncertainty on e-commerce goods distribution, with a discrete optimization framework formulating a last-mile network design (LMND) problem as a dynamic-stochastic two-echelon capacitated location routing problem with time-windows (DS-2E-C-LRP-TW), addressed using an adaptive large neighborhood search (ALNS) metaheuristic algorithm
