1,721,355 research outputs found

    METHOD AND COMPOSITIONS FOR THE APPLICATION OF AMINO ACIDS ON THE SKIN THROUGH AN ANHYDROUS MEAN

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    A formulation for topical, dermatologic and/or cosmetic use, in form of hydrophobic gel, oleolite or butter comprising at least one amino acid, at least one hydrophobic vehicle such as oil, silicone or butter, a porous polymer and/or a 'spider ester' and/or micro-and nano-particle carriers and vesicular carriers, molecular inclusion systems, thickeners and hydrophobic phase stabilisers, hydrogenating oils, silicone waxes and non-silicone waxes such as bee waxes, silica

    Metodi e composizioni per l’applicazione di aminoacidi sulla pelle mediante un mezzo anidro.

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    Una metodo a base di amminoacidi per la prevenzione e/o il trattamento dermatologico e/o cosmetico dei danni della pelle e degli annessi cutanei, in particolare unghie e capelli per uso in applicazioni per idratazione, accelerazione dei tempi di guarigione delle ferite, per efficacia antietà, azione antibatterica, azione schiarente/illuminante, trattamento di herpes e psoriasi, azione antiossidante e detossificante, effetto barriera

    Topical Vitamins A, C, E monodoses: from cosmeceuticals application to skin nutrition.

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    An old problem of topical dermo-cosmesis and dermatology is represented by the quantity of product or drug that the subjecy applies and its compositions in terms of number and concentration of ingredients. Many (perhaps all) of the dermatologists must be accustomed to using outdated terminology and generic descriptions, which includes phrases like "two applications per day" or "a veil at evening" and so on. The truth is that we do not know how much product or medication the subject apply. Vitamins A, C and E are joined by a common difficulty in formulation: the first and last with fat-soluble character, the second water-soluble; they are active in the biologically free form, highly instable to light and oxygen. This has meant that strategies have been developed to make them usable in dermatology. Do not underestimate the aspect of pleasantness that the finished product must have. A product unappealing (spreadability, odor, stability) is unlikely to be effective, as little or incorrectly applied. A novel monodoses delivery/application approach will be presented

    Prodotti cosmetici a connotazione naturale e sostenibile

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    Si tratta di un corso unico nel panorama Nazionale ed Internazionale e viene indirizzato sia agli studenti dei Corsi di laurea in Farmacia, Farmacia Industriale, Biologia, Biotecnologie e Chimica come supporto allo studio della materia, sia al professionista che opera nel settore del consiglio del prodotto cosmetico e, in particolare, di quello Natural

    A, B, C, E L’alfabeto del benessere: Vitamine Topiche nel Trattamento degli Inestetismi Cutanei

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    Le vitamine sono una componente indispensabile della pelle umana e fanno parte di un sistema di difesa che protegge la pelle dallo stress ossidativo. C'è un crescente interesse nell'impiego di molecole naturali come le vitamine per contribuire a ripristinare attività antiossidante cutanea compromessa da stimoli noxa sia endogeni che esogeni. Vitamine A, C, E, B3 hanno dimostrato di essere potenti antiossidanti con proprietà anti-infiammatorie, ma per garantire un'efficacia ottimale, i prodotti devono essere presentati nelle formulazioni appropriate. I prodotti che contengono [alpha]-tocoferolo (vitamina E), acido L-ascorbico (vitamina C), retinolo (vitamina A), e niacinamide (vitamina B3), sono efficaci per il trattamento del photoaging e dell’invecchiamento cutaneo accelerato. Queste vitamine hanno dimostrato inoltre efficacia nel mantenimento dello stato di salute della pelle, nel pre- e post-trattameto estetico e nella prevenzione della dermatosi infiammatoria, acne e disturbi della pigmentazione e riparazione cutanea. Nel corso della presentazione verranno presentati recenti risultati sulla relazione struttura attività delle vitamine in pre e post trattamento in condizioni di foto-aging e stress ossidativo

    Prodotti da forno

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    prodotti da forno salutistici adatti per il mantenimento del buon stato di salute, in particolare in soggetti affetti da problemi cardiocircolatori, sovrappeso, osteoporosi, menopausa, sindrome metabolic

    Adenosine A1 receptor: Analysis of the potential therapeutic effects obtained by its activation in the central nervous system

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    Adenosine modulates several physiological functions in the CNS and in peripheral tissues via membrane receptors which have been classified into four adenosine subtypes. A(1) activation produces neuronal depression: this inhibition allows A(1) agonists to produce ischemic tolerance and protection in neuronal tissue. In order to selectively reproduce these effects, several A(1) selective ligands have been synthesised and evaluated to understand how they interact with the adenosine A(1) receptor. The investigation methods include SAR studies using native and chemically modified A(1) receptors, molecular cloning of native and mutant adenosine A(1) receptors, molecular modeling and thermodynamic analysis of drug-receptor interaction. Despite the great quantity of information available on the adenosine A(1) receptor, no A(1) agonist has so far entered in clinical use against brain diseases in view of the side effects; moreover selective A(1) agonists appear to be poorly adsorbed into the brain and can be quickly degraded in vivo or in the whole blood. In an attempt to overcome these problems studies have been undertaken dealing with the use of partial agonists to inhibit side-effects and the employment of prodrugs to increase stability and diffusion through lipid barriers of A(1) ligands. Other attempts involve either the use of A(1) receptor enhancers as modulators able to locally enhance the action of endogenously produced adenosine, or the encapsulation of A(1)agonists in drug delivery systems targeted to the brain. In this review, these approaches will be described together with the effects of adenosine A(1) receptor ligands and their binding mechanisms on the central nervous system

    Le traitement de la gale en Italie au XIXe siècle. Vincentini (Chiara B.), Altieri (Lorenzo), Manfredini (Stefano), «The treatment of scabies in Ferrara (Italy) in the 19th century», Pharmacy in History, 2012

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    Labrude Pierre, Bourrinet Patrick, Bonnemain Bruno. Le traitement de la gale en Italie au XIXe siècle. Vincentini (Chiara B.), Altieri (Lorenzo), Manfredini (Stefano), «The treatment of scabies in Ferrara (Italy) in the 19th century», Pharmacy in History, 2012. In: Revue d'histoire de la pharmacie, 100e année, N. 378-379, 2013. pp. 283-284

    Succédanés du quinquina. Vincentini (Chiara B.), Altieri (Lorenzo), Manfredini (Stefano), «À la recherche de succédanés du quinquina en Italie au XIXe siècle» (“ In Search of Cinchona Substitutes in Nineteenth-Century Italy”), Pharmacy in History, 2012

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    Bonnemain Bruno. Succédanés du quinquina. Vincentini (Chiara B.), Altieri (Lorenzo), Manfredini (Stefano), «À la recherche de succédanés du quinquina en Italie au XIXe siècle» (“ In Search of Cinchona Substitutes in Nineteenth-Century Italy”), Pharmacy in History, 2012. In: Revue d'histoire de la pharmacie, 100e année, N. 378-379, 2013. pp. 285-286
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