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    Case Report: Laparoscopic Cholecystectomy in a Patient with Situs Inversus Totalis

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    Background: Situs inversus totalis is inherited as an autosomal recessive trait and occurs in approximately 1 per 10 to 20.000 live births. It’s definite as the transposition of both the thoracic and abdominal viscera to the opposite side of the body. Case Presentation: D.D. was a 42 y old man who experienced 6 months prior of his presentation intermittent nausea,intermittent epigastric pain that radiated laterally to both sides of upper abdomen,shoulder pain and bloating after some meals. He received an abdominal US that showed the presence of gallstones without biliary tree distention, with gallbladder wall thickening. Patient underwent laparoscopic cholecystectomy. The operation was carried out in the usual manner with the trocars placed in locations on the left side of the abdomen as mirror images to their usual location on the right side. On laparoscopic examination the intra-abdominal anatomy was the mirror image of the normal view. Dissection of the triangle Calot and application of the clip and gallbladder dissection was performed by operator’s left hand through the subxiphoid trocar. Conclusions: Some authors suggest that laparoscopic cholecystectomy in patients with left-sided gallbladder is preferred to be performed by left handed surgeons due to better ergonomy; we suggest that surgeon should be right and left handed with experience in laparoscopy and hepatobiliary surgery

    Is long-lasting mucosal elevation the only valid parameter when evaluating a lifting agent?

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    Stefano Pontone, Simone Manfredelli, Dimitri Krizzuk, Giovanni LeonettiDepartment of Surgical Sciences, “Sapienza” University of Rome, Rome, ItalyDear editorConsidering the relevance of the topic, our attention was strongly attracted by the study reported by Al-Taie et al. This study, based on our experience, begs some questions. Although the limitations of the lifting agent have been correctly identified by the authors, it would be useful to know the timing and details of the procedures used for preparation of blood, plasma, and serum

    Dietary chemoprevention of colorectal cancer

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    AIMS AND BACKGROUND: Colorectal cancer is the second cause of morbidity and death in Italy. Genetic and environmental factors, i.e. inappropriate nutrition, are strongly involved in the aetiology of colon cancer. In the present review the authors analyze the possible mechanisms by which certain nutritive factors may interfere with the complex process of carcinogenesis. METHODS: The authors identify studies by a literature search of Medline from January 1, 1970, through December 31, 2006. RESULTS: The mechanism of every protective compound is detailed, in particular the impact of antioxidant vitamins and minerals on tumor development. At present, the data suggest that vegetables are associated with lower risk and that their fbre content alone does not account for this association. Further, meat consumption is associated with an increased risk but this, too, is not explained solely by its fat content. Several microconstituents of the diet may be associated with reduced risk, including folate, methionine, calcium and vitamin D. Short chain fatty acids also contribute to colonic health. Nevertheless agricultural products contain several dangerous pesticides. Mutagenic compounds, particularly heterocyclic amines, produced when protein is cooked, plausibly explain the meat association. CONCLUSIONS: Healthy nutrition is a necessary but not sufficient condition for colon cancer prevention: accepted the feasibility of an accurate control on every patient's diet, fequently the difficulty encountered in nutritional chemoprevention is to establish individual metabolic profiles

    An inguinal bladder diverticulum Case report of a rare finding in a recurrent inguinal hernia.

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    We report a rare case of recurrent right inguinal hernia with bladder diverticulum incarcerated in a 63 years old male. Patient complained of painful swelling in inguinoscrotal region associated with urinary discomfort. Preoperatively diagnosis was made possible by ultrasound and urography imaging. Surgical treatment was achieved, by infra-umbilical incision, a reduction of the herniated and fixed diverticulum followed by a mesh repair of the wall defect. Patient was discharged five days after surgery and became free of symptomatology soon after surgical procedure. Bladder diverticulum involvement in a direct inguinal hernia is rare finding and define a potential pitfall for surgeon if not diagnosed preoperatively. There are no other cases of incarcerated bladder diverticulum incarcerated in a recurrent inguinal hernia described in Literature. KEY WORDS: Bladder diverticulum, Bladder hernia, Inguinal hernia

    Extraskeletal Ewing's Sarcoma: insight into a ten years follow-up.

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    Extraskeletal Ewing’s sarcoma is a rare malignant soft tissue tumor, classified within the Ewing’s Sarcoma Family Tumors. While the classical Ewing’s Sarcoma affects mainly the bone during youth, the Extraskeletal histotype differs for age incidence, primary location and prognosis. Peak incidence and typical location are during adolescence and in the extremities respectively. We report a 30 year old woman case with a positive outcome after ten years from first diagnosis of Extraskeletal Ewing’s sarcoma. Treatment was achieved through surgical resection plus adjuvant chemoradiotherapy derived from EW93 and IRS III trials
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