416 research outputs found
2018-2019 Garth Greenwell
No full textGarth Greenwell is the author of What Belongs to You, which won the British Book Award for Debut of the Year, was longlisted for the National Book Award, and was a finalist for six other awards, including the PEN/Faulkner Award, the James Tait Black Memorial Prize, and the Los Angeles Times Book Prize. A New York Times Book Review Editors\u27 Choice, it was named a Best Book of 2016 by over fifty publications in nine countries, and is being translated into a dozen languages. A new book of fiction, Cleanness, is forthcoming from FSG in early 2020. His fiction has appeared in The New Yorker, The Paris Review, A Public Space, and VICE, and he has written criticism for The New Yorker, the London Review of Books, and the New York Times Book Review, among others. He lives in Iowa City. (Photo credit: Bill Adams)https://egrove.olemiss.edu/grisham_res/1001/thumbnail.jp
Garth Greenwell, 40th Annual ODU Literary Festival
No full textGarth Greenwell is the author of What Belongs to You, which won the British Book Award for Debut of the Year, was longlisted for the National Book Award, and was a finalist for six other awards, including the PEN/Faulkner Award, the James Tait Black Memorial Prize, and The Los Angeles Times Book Prize. A New York Times Book Review Editors\u27 Choice, it was named a Best Book of 2016 by over fifty publications in nine countries, and is being translated into eleven languages. His short fiction has appeared in The New Yorker, the Paris Review, and A Public Space, and he has written criticism for The New Yorker, The London Review of Books, and The New York Times Book Review, among others. He lives in Iowa City
Advances and Current Status in the Use of Cuticular Hydrocarbons for Forensic Entomology Applications
No full textCuticular hydrocarbons (CHCs) are long-chain lipids found on the exoskeletons of insects, serving primarily as a protective barrier against water loss and environmental factors. In the last few decades, the qualitative and quantitative analysis of CHCs, particularly in blow flies, has emerged as a valuable tool in forensic entomology, offering promising potential for species identification and age estimation of forensically important insects. This review examines the current application of CHC analysis in forensic investigations and highlights the significant advancements in the field over the past few years. Studies have demonstrated that CHC profiles vary with insect development, and while intra-species variability exists due to factors such as age, sex, geographical location, and environmental conditions, these variations can be harnessed to refine post-mortem interval (PMI) estimations and improve the accuracy of forensic entomological evidence. Notably, CHC analysis can also aid in distinguishing between multiple generations of insects on a body, providing insights into post-mortem body movement and aiding in the interpretation of PMI in complex cases. Furthermore, recent studies have investigated the variability and degradation of CHCs over time, revealing how environmental factors—such as temperature, humidity, UV light exposure, and toxicological substances—affect CHC composition, providing valuable insights for forensic investigations. Despite the promise of CHC profiling, several challenges remain, and this review also aims to highlight future research directions to enhance the reliability of this technique in forensic casework
Sovereign desires. by Garth Nettheim
No full textSelf-determination has been at the heart of Aboriginal aspirations. As a slogan, it echoes through the twentieth century. The author argues that sovereignty is rarely defined, and often misunderstood. Provided by MICAH, Canberra
Garth St. Omer's Existential Parlance
No full textPurpose of the Study: Garth St. Omer, a contemporary Caribbean author of novellas, develops many themes in his fiction that maybe found in fictional and philosophical writings by Albert Camus, Jean-Paul Sartre, and other French existentialists. This study ;s an attempt to trace and delineate some of the themes, motifs, and aesthetic techniques common to both St. Omer and the French existentialists. Procedure: In this investigation, a close reading of the works of Garth St. Omer, Albert Camus, and other French Existentialists, has been conducted. In addition, criticism of St. Omer's works and volumes devoted to genre and style have been consulted. A final assimilation, comparison, and integration of these texts has been carried out in an attempt to construct an itinerary of St. Omer's thought. Findings: The particular novella genre developed by Garth St. Omer, as well as his concentrated prose, sets his writings apart from those of the French existentialists. The aesthetic techniques combined with the philosophical themes implicit in his stories give rise to types of alienation and existential experience unique to St. Omer's characters. Conclusions: The parallels that exist between the writings of St. Omer and the French existentialists cannot be relegated to mimesis. For a deep reading of St. Omer's fiction shows that his themes are not variations of Camus's and Sartre's themes (as some critics argue), but rather extensions of a vision that St. Omer and these other artists shared; the central hypothesis being that Garth St. Omer is as independent of Camus and Sartre as he is indebted to them.Gifford, William Tell. 1988. Garth St. Omer's Existential Parlance. Department of English, Sonoma State University
Garth St. Omer's Existential Parlance
No full textPurpose of the Study: Garth St. Omer, a contemporary Caribbean author of novellas, develops many themes in his fiction that maybe found in fictional and philosophical writings by Albert Camus, Jean-Paul Sartre, and other French existentialists. \ud
This study ;s an attempt to trace and delineate some of \ud
the themes, motifs, and aesthetic techniques common to \ud
both St. Omer and the French existentialists. \ud
Procedure: In this investigation, a close reading of the works of Garth St. Omer, Albert Camus, and other French Existentialists, has been conducted. In addition, criticism of St. Omer's works and volumes devoted to genre and style have been consulted. A final assimilation, comparison, and integration of these texts has been carried out in an attempt to construct an itinerary of St. Omer's thought. \ud
Findings: The particular novella genre developed by Garth St. Omer, as well as his concentrated prose, sets his writings apart from those of the French existentialists. The aesthetic techniques combined with the philosophical themes implicit in his stories give rise to types of alienation and existential experience unique to St. Omer's characters. \ud
Conclusions: The parallels that exist between the writings of St. Omer and the French existentialists cannot be relegated to mimesis. For a deep reading of St. Omer's fiction shows that his themes are not variations of Camus's and Sartre's themes (as some critics argue), but rather extensions of a vision that St. Omer and these other artists shared; the central hypothesis being that Garth St. Omer is as independent of Camus and Sartre as he is indebted to them
The economic impact of snowmobiling in Valley County
No full textBulletin no. 844 Moscow, Idaho :University of Idaho, College of Agriculture, Agriculture Experiment Station, 2006-07-01. Author(s): Larsen, Ryan; Taylor, Garth; Hines, Stev
Politics and the Payne Fund
No full textGarth Jowett discusses the Payne Fund Studies, which were a series of studies conducted to examine the effects of motion pictures on American Youth. The author examines how the “Payne Fund attempted to neutralize the potential conflicts which might have arisen once the studies were finally made public, and to minimize the impact of any potential backlash from the motion picture industry”. Conference paper; originally published in Western Reserve Studies Symposium (10th:1995 : Cleveland, Ohio
Characterising biochemical changes to hepatocellular carcinoma (HepG2) cells upon exposure to green tea extract using untargeted metabolomics
No full textComplementary and alternative medicines (CAMs) have become the preferred medicine for many in replacement of conventional medicines due to cultural or financial reasons. Herbal CAMS, in particular, have become a popular choice of medicine for their purported health benefits. Green tea extract (GTE) contains the major catechins epigallocatechin-3-gallate, epicatechin gallate, epigallocatechin and epicatechin, all of which vary across different GTE products and have become the focus on research into its purported health benefits. However, there have been cases of GTE-induced hepatotoxicity, for which the biochemical pathways have not been characterised. This study elucidates compounds similarities and changes in catechin levels within several different GTE products, and biochemical pathways related to reactive oxygen species (ROS) production affected by acute GTE supplementation in an in vitro setting using metabolomic techniques. It was found that GTE hepatotoxicity significantly decreased amino acids, oxoacids and carboxylic acids at 1 mg/mL exposure but produced a different metabolite profile upon 0.1 mg/mL exposure. The results demonstrate that GTE hepatotoxicity is a dose-dependent process that induces ROS production, ATP depletion and apoptosis, which corroborates prior knowledge on this topic. These results utilise a novel field of research, metabolomics, to add insight into the biochemical mechanisms of GTE hepatotoxicity and to observe the mass spectral pattern and levels of four catechins in different GTE products: (+)-catechin, (-)-epicatechin, (-)-epigallocatechin and (-)-epigallocatechin-3-gallate. This will allow consumers to become more aware of herb-induced liver injury and provide data to aid the regulation of herbal CAMs
Acute and chronic toxicity of methamphetamine exposure in cultured neuronal cells
No full textMethamphetamine is a highly addictive psychostimulant drug with serious health consequences that include long-term neurotoxic effects. While the neurotoxic mechanisms are still not fully understood, monoamine release, production of reactive oxygen species and excitotoxicity are believed to be involved. There is currently no effective treatment to prevent these effects. Using metabolomic analysis to explore the effect of methamphetamine on neuronal cells with dose and time may help to elucidate the biochemical pathways affected, and provide an insight into methamphetamine neurotoxicity.
A B50 neuroblastoma cell culture model was used in these experiments. Cell viability was assessed by lactate dehydrogenase assay and Trypan blue exclusion testing after 48 hours exposure to 1 mM methamphetamine. A dose curve was conducted exposing cells to a range of methamphetamine doses (100 nM, 1 μM, 10 μM, 100 μM and 1 mM) over 48 hours. A time course examined the 6-, 24- and 48-hour time points after B50 exposure to 1 mM methamphetamine. A gas chromatography-mass spectrometry metabolomic method was used to analyse the treated cells and cell media of the dose curve and time course. The metabolites found to contribute most to the variance between the samples were chosen for further study.
Methamphetamine caused observable damage to B50 cells and cell viability which was found to be dose-dependent by Trypan blue testing, however, LDH results were inconclusive. The metabolites found to change over dose and time during methamphetamine exposure included amino acids, carbohydrates and fatty acids. The dose curve showed a build-up of carbohydrates, a decrease in octadecenoate and alterations to many amino acids with increasing dose. The results from the time course found an increase in L-glutamate and related metabolites, an increase in antioxidant amino acids and a decrease in carbohydrates over time. The changes suggest glutamate release, reactive oxygen species and disturbances to energy utilisation may be involved in the effect of methamphetamine upon neuronal cells.
The study has confirmed that methamphetamine causes dose-dependent damage and death of neurons. Methamphetamine exposure resulted in quantifiable biochemical changes over dose and time with the metabolite changes reflecting the known mechanisms of methamphetamine neurotoxicity. The result of this study furthers our understanding of neurochemical processes in response to methamphetamine and could potentially lead to the identification of therapeutic targets
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