103 research outputs found
The integrative panel of fatty acid desaturase-2 (FADS2) rs174583 gene polymorphism and dietary indices (DQI-I and HEI) affects cardiovascular risk factors among obese individuals
No full textBackgroundRecent studies have shown that dietary intakes and gene variants have a critical role in the obesity related comorbidities. This study aimed to evaluate the effects of the interactions between Fatty acid desaturase 2 (FADS2) gene rs174583 polymorphism and two dietary indices on cardiometabolic risk factors.MethodsThis cross-sectional study was carried out on 347 obese adults aged 20-50 years old in Tabriz, Iran. Healthy eating index (HEI) and Diet quality index-international (DQI-I) were evaluated by a validated semi-quantitative 147-item Food frequency questionnaire (FFQ). Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to determine FADS2 gene variants. Multivariate analysis of covariance (MANCOVA) was used to identify gene-diet interactions on metabolic parameters.ResultsWaist circumference (WC) and serum triglyceride (TG) levels were significantly higher among carriers of TT genotype of FADS2 gene (P < 0.05). In addition, the interactions between FADS2 gene rs174583 polymorphism and DQI-I had significant effects on weight (P (interaction) = 0.01), fat mass (P (interaction) = 0.04), fat free mass (P (interaction) = 0.03), and Body mass index (BMI) (P (interaction) = 0.02); the highest level of these parameters belonged to TT carriers. Similarly, the interactions between FADS2 gene variants and HEI had significant effects on insulin (P (interaction) < 0.001), Homeostasis model assessment of insulin resistance (HOMA-IR) (P (interaction) < 0.001), Quantitative insulin check index (QUICKI) (P (interaction) = 0.001), and alpha Melanocyte stimulating hormone (alpha-MSH) (P (interaction) = 0.03).ConclusionIn this study, for the first time, we reported the effects of gene-diet interactions on metabolic traits. Compliance with dietary indices (DQI-I and HEI) ameliorated the adverse effects of gene variants on metabolic risk factors, especially in heterogeneous genotypes. Further prospective cohort studies are needed to confirm these results
114 - Mahsa Ghorbani
No full textStock price prediction is one of the most challenging problems in finance and is receiving considerable attention from researchers. The literature provides strong evidence that prices can be predicted from past price data as well as other fundamental and macroeconomic variables. We propose a filtering operation using covariance information in order to predict future stock prices. We use daily historical price data for Generals Electric Company to illustrate our method, which shows promising results in terms of the estimation performance and volatility
Nurturing success with learning disabilities in French immersion with teachers' and parents' support and collaboration
No full textThis paper draws upon my six years of teaching French as the second or foreign languages as well as my academic experiences in the Master of Education program. Within the past six years, I have perceived the second language acquisition to be an enjoyable and pleasant journey for all my students similar to what I experienced as a child. However, having faced various learning styles and needs as well as the uncertainty of some parents about the placement of their children with learning disabilities in French Immersion, I gravitated to inquire more into the compatibility of this program for my at-risk students. The French Immersion program is suitable for the students with learning disabilities if they can be provided with proper support in positive and motivating learning environments, such as school and home. This knowledge would benefit the teachers and parents who need to be ensured that the inclusion of the students with learning difficulties in French Immersion is educationally sound. Through the analysis of different strategies and accommodations, this paper discusses how the students with learning disabilities and their families can address their concerns and avoid some challenges, such as transition to English-only programs after having built several years of connections and friendships and the associated social-emotional impacts. This paper also seeks to convey the message to the teachers that learning disability should not hinder language acquisition. The implications emerged from this awareness are that educators and parents can advocate for the students with learning disabilities through their collaborative efforts, so that they can have equitable access to learning French in supportive and inspirational learning environments.Not peer reviewedcapstoneFrench immersionlearning disabilitysecond language acquisitioninclusionary practiceshome-school collaborationhome-school collaboratio
Hypothalamic-pituitary hormones will be affected by the interaction between 5q13-14-rs2239670 (CARTPT) gene variants and diet in different obesity phenotypes
No full textObjective Evidence show that cocaine and amphetamine regulated transcript-prepropeptide (CART-PT) gene variants may affect obesity related traits, but little is known about its end points. In the current study, we aimed to evaluate the interaction of CARTPT gene polymorphism with diet quality indices including dietary approaches to stop hypertension (DASH) and Mediterranean diet score (MDS) on cardio-metabolic risk factors. This cross sectional study recruited 288 apparently healthy obese individuals. Diet quality indices including DASH and MDS were evaluated using semi quantitative food frequency questionnaire (FFQ). Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used for CARTPT genotypes. Results No significant differences was reported for general characteristics and biochemical parameters across genotypes except for QUICKI among females (P = 0.01) and it was higher in heterozygous genotype. There was significant CARTPT-DASH interactions affecting serum fasting glucose level (P = 0.049). However, in relation to CERTPT-MDS interactions, the highest level of insulin (P = 0.003) and HOMA-IR (P = 0.003) values were shown among AA carriers in high adherence to MDS, while AA carriers in high compliance to MDS experienced decreased level of QUICKI (P = 0.001)
Structural changes of conversion metal fluoride cathodes in lithium ion batteries
No full textCurrently, cathode materials for Li-ion batteries are based on intercalation processes where, during charge and discharge processes, Li intercalates into the crystal lattice while maintaining the host crystal structure. More recently, new cathode materials have been introduced based on conversion reactions involving phase transformation and complete reduction of the host transition metal. In addition, conversion reactions involve two or more Li ions with a resulting much higher capacity than obtainable for intercalation materials. However, mechanism of phase transformation and cycling reversibility are at present still poorly understood. In this study transmission electron microscopy (TEM) techniques including selected area electron diffraction (SAED) pattern, annular dark field (ADF) STEM image, and electron energy loss spectroscopy (EELS) with nanoscale spatial resolution were used to study the phase evolution and structural changes of iron fluorides (FeFe2, FeO0.7F1.3, FeF3) after various discharge/charge cycles. Additionally, the changes of the Fe valence states upon cycling were determined using EELS by measuring the L3/L2 intensity ratio of Fe-L edge. The structural transformations of FeO0.7F1.3 during the first lithiation show that litiahation contains two regions. The first region, lithiation is an intercalation reaction iii with reduction of Fe3+ to Fe2+. The second region of lithiation involves a conversion reaction, with the formation of metallic Fe, LiF, and Li0.7Fe2+0.5O0.7F0.3 (rocksalt type) phases. The first delithiation process follows a different conversion reaction path compared to the first lithiation reaction involving the formation an amorphous rutile-type phase along with with the rocksalt-type phase. Interestingly, upon full recharge (delithiated electrode), the measured average Fe valence state returns back to its initial value of Fe2.7+. The growth of a solid electrolyte interphase (SEI) layer formation at the electrode/electrolyte interface is observed for the iron fluoride compounds (FeF2, FeF3, and FeOF) after cycling. The evolution of the SEI layer formation after cycling has been studied for the FeF2 samples in details by EELS and XPS. We observed the growth of SEI layer with cycle number, which mainly contained LiF and Li2CO3 compounds. Two degradation mechanisms are identified. First, the increase in the decomposition product layer after cycling inhibits complete reconversion process. Second, dissolution of Fe into the SEI layer after cycling which leads to the loss of active material.Ph.D.Includes bibliographical referencesby Mahsa Sin
Nutrition and wound healing: vitamins
No full textSufficient nutrition is important for all medical surgical patients. In the clinical setting, many patients postoperative receive multivitamin and minerals to maintain adequate nutrition. This poster presentation will address the importance of supplementary vitamins to wound healing. Complications of delay wound healing includes adhesions, contractures, dehiscence, evisceration, granulation tissue, fistula formation, Infection, hemorrhage, formation of
hypertrophic scars and keloids (Lewis, Dirksen, Heitkemper, Bucher, & Camera, 2014). Conclusion: through this project we have learned that malnutrition contributes to delayed wound healing. Each vitamin we have discussed plays an important role in each stage of the healing process: inflammatory, proliferative and remodeling phase. Based on our literature review, patients who were receiving nutritional supplementation displayed a significant decrease in wound size as compared to those who did not. We now have a better understanding of supplemental nutrition (vitamins) on post surgical patients in our clinical setting and will further promote these findings through patient teaching.Not peer reviewedStudent Research Day Poster (2017
Additional file 1 of Hypothalamic-pituitary hormones will be affected by the interaction between 5q13-14-rs2239670 (CARTPT) gene variants and diet in different obesity phenotypes
No full textAdditional file 1: Fig. S1.Full length, original unprocessed gels of CART rs2239670 genotyping by Apa-I PCR-RFLP analysis. M: 50 bp DNA ladder
Triggering Social Entrepreneurship Initiatives: Investigating the role of Dutch national government policy in triggering social entrepreneurship initiatives focusing on delivering affordable owner-occupied housing
No full textThe Netherlands is currently facing a shortage of affordable housing, specifically for middle-income households. These households with too much income to qualify for social housing but not enough to buy a home tend to squeeze into the free rental market increasingly. Housing specifically targeted at this group is known as intermediate housing, which is provided at a cost above social rent but below market rates. In previous years, very few houses for this target group were developed due to the reluctance of the market to develop these homes due to lower profitability and strict regulations that made it difficult for local governments and social housing associations to build and distribute intermediate housing. This study's primary goal is to reduce the inequality gap in the Dutch housing market by designing a national government housing policy. As a response to the shortage of affordable housing among middle-income households, it has been proposed that more social enterprises should become active in the housing sector as well as in other industries which solve societal problems by combining economic mission and societal impact. Social housing enterprises can explicitly address the shortage of affordable housing for middle-income households, unlike commercial ones that are solely concerned with profits. Furthermore, these newly developed Social Housing Enterprises are not subject to strict rules regarding the distribution of housing to middle-income households. As a result, they might be able to address the housing shortage.The research question is "How can national government policy trigger social entrepreneurship initiatives focusing on delivering affordable owner-occupied housing?". For this research, a qualitative approach has been taken, in which primary and secondary data are used. The primary data came from ten semi-structured in-depth interviews, and the secondary data came from the literature review. In general, the national government's involvement increases the likelihood of individuals engaging in Social Entrepreneurship and its formation. The result showed that government support for removing barriers to social enterprise creation was the most important factor driving social entrepreneurship. Governments can lower barriers to social enterprises in the provision of intermediate housing by giving formal recognition, improving access to markets and finances, providing in-kind resources, and strengthening skills to trigger social entrepreneurship initiatives focusing on delivering affordable owner-occupied housing.Graduation laboratoryArchitecture, Urbanism and Building Sciences | Management in the Built Environmen
Electrospun core-shell nanofibers based on thermoplastic urethane elastomer and gelatin: Evolution of cell behavior
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