196,574 research outputs found
Portraying Mahalakshmi as an Awe-inspiring Mistress: An Exploration of M. Kumaran S/o Mahalakshmi
No full textMaria Shriver, an American journalist and activist has expressed that having kids - the responsibility of rearing good, kind, ethical, responsible human beings - is the biggest job anyone can embark on, which is a widely accepted truth, notwithstanding to the boundaries of time, culture and nativity. The research paper aims at exploring the episodes of the movie, M.Kumaran S/o Mahalakshmi that assist in substantiating the proclamation of Maria Shriver. The research paper attempts to scrutinize and reiterate the determination of the single-handed Mahalakshmi who plays a successful and inspiring role in all her capacities. Mahalakshmi is a prominent and inspiring woman character of the 2004 Tamil family-drama film, M.Kumaran S/o Mahalakshmi that was directed by M. Raja. Being a woman character, she has influenced millions of souls of different backgrounds remarkably. Having deserted by her lovely husband Eshwar, Mahalakshmi moves to a strange city with her sole boy child wherein she strives to become a college Lecturer, thereby constructing her and her son, Kumaran’s life
Synthesis, Spectral Analysis, DFT and Antimicrobial of Some Novel Benzimidazole Derivatives
No full textTwo novel 2 substituted benzimidazole derivatives were synthesized from 2 chloromethyl 1H benzimidazole and 2 2 chlorophenyl 1H benzo d imidazole with 1H 1,2,4 triazol 3 amine. Their structures were characterized by Infrared spectroscopy, Nuclear magnetic resonance, 1H, 13C , Elemental analysis. Density functional theory DFT studies were performed using the B3LYP 6 31G d, p basis set to expand imminent into their structural properties. All the synthesized compounds were screened for antimicrobial activity against a panel of selected bacterial and fungal strains using ciprofloxacin and fluconazole as standards. C. M. Mahalakshmi "Synthesis, Spectral Analysis, DFT and Antimicrobial of Some Novel Benzimidazole Derivatives" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, URL: https://www.ijtsrd.com/papers/ijtsrd14595.pd
The Success of the Montreal Protocol for Climate Mitigation: Antarctica Ozone hole Recovery Perspective
No full textThe monitoring of the ozone in the Earth’s atmosphere began in the 1970s due to its absorbing nature of radiation from the Sun, which is harmful to humans and prevents it from reaching the surface of the Earth. However, considerable global attention has been drawn after the finding of the ozone hole, which is associated with a significant drop in total columnar ozone (TCO), specifically a fall in stratospheric ozone (SO) during the spring of 1984. Since then, numerous studies on the Antarctic ozone hole have been conducted following the Vienna Convention and its Montreal Protocol (the ozone treaties) to sustain the ozone layer. In response to this, the Montreal Protocol was developed under the umbrella of the United Nations Environment Programme (UNEP) to protect the thinning of the ozone layer. With 197 participating nations, it is a substantial step toward universal ratification.
Towards this, the present study utilized TCO data from the National Aeronautics and Space Administration (NASA)'s Nimbus-7/Total Ozone Mapping Spectrometer (TOMS), TOMS-Earth Probe, and Aura/Ozone Monitoring Instrument (OMI) sensors at various time periods. Due to the varied spatial resolution of the missions, daily data were resampled to 1˚×1˚ (latitude × longitude) and generated daily unified spatial resolution matrixes.
S.No.
Parameter
Sensor
Data Period
Resolution in degrees
(Latitude × Longitude)
Data Resource
1
Total Columnar Ozone (TCO)
NIMBUS-7/TOMS
1979-1993
1°×1.25°
https://earthdata.nasa.gov/
2
TOMS-EP
1996-2005
1°×1.25°
https://earthdata.nasa.gov/
3
AURA/OMI
2004-2020
0.25°×0.25°
https://earthdata.nasa.gov/
4
Ozone Depleting Substances (ODS) emissions
1985-2015
Global data
https://ourworldindata.or
Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling
No full textAbstractCXCL12 and its unique receptor CXCR4, is critical for the homing of a variety of cell lineages during both development and tissue repair. CXCL12 is particularly important for the recruitment of hemato/lymphopoietic cells to their target organs. In conjunction with the damage-associated alarmin molecule HMGB1, CXCL12 mediates immune effector and stem/progenitor cell migration towards damaged tissues for subsequent repair. Previously, we showed that cell migration to HMGB1 simultaneously requires both IKKβ and IKKα-dependent NF-κB activation. IKKβ-mediated activation maintains sufficient expression of HMGB1's receptor RAGE, while IKKα-dependent NF-κB activation ensures continuous production of CXCL12, which complexes with HMGB1 to engage CXCR4. Here using fibroblasts and primary mature macrophages, we show that IKKβ and IKKα are simultaneously essential for cell migration in response to CXCL12 alone. Non-canonical NF-κB pathway subunits RelB and p52 are also both essential for cell migration towards CXCL12, suggesting that IKKα is required to drive non-canonical NF-κB signaling. Flow cytometric analyses of CXCR4 expression show that IKKβ, but not IKKα, is required to maintain a critical threshold level of this CXCL12 receptor. Time-lapse video microscopy experiments in primary MEFs reveal that IKKα is required both for polarization of cells towards a CXCL12 gradient and to establish a basal level of velocity towards CXCL12. In addition, CXCL12 modestly up-regulates IKKα-dependent p52 nuclear translocation and IKKα-dependent expression of the CXCL12 gene. On the basis of our collective results we posit that IKKα is needed to maintain the basal expression of a critical protein co-factor required for cell migration to CXCL12
sj-docx-3-dhj-10.1177_20552076231222112 - Supplemental material for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia
No full textSupplemental material, sj-docx-3-dhj-10.1177_20552076231222112 for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia by Victoria Loblay, Mahalakshmi Ekambareshwar, Aila Naderbagi and
Yun JC Song, Michele Ford, Iqthyer Zahed, Adam Yoon,
Ian B Hickie, Haley M LaMonica in DIGITAL HEALTH</p
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
sj-docx-4-dhj-10.1177_20552076231222112 - Supplemental material for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia
No full textSupplemental material, sj-docx-4-dhj-10.1177_20552076231222112 for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia by Victoria Loblay, Mahalakshmi Ekambareshwar, Aila Naderbagi and
Yun JC Song, Michele Ford, Iqthyer Zahed, Adam Yoon,
Ian B Hickie, Haley M LaMonica in DIGITAL HEALTH</p
sj-docx-1-dhj-10.1177_20552076231222112 - Supplemental material for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia
No full textSupplemental material, sj-docx-1-dhj-10.1177_20552076231222112 for Enhancing equitable engagement for digital health promotion: Lessons from evaluating a childrearing app in Indonesia by Victoria Loblay, Mahalakshmi Ekambareshwar, Aila Naderbagi and
Yun JC Song, Michele Ford, Iqthyer Zahed, Adam Yoon,
Ian B Hickie, Haley M LaMonica in DIGITAL HEALTH</p
sj-docx-4-dhj-10.1177_20552076241242559 - Supplemental material for Promoting social, emotional, and cognitive development in early childhood: A protocol for early valuation of a culturally adapted digital tool for supporting optimal childrearing practices
No full textSupplemental material, sj-docx-4-dhj-10.1177_20552076241242559 for Promoting social, emotional, and cognitive development in early childhood: A protocol for early valuation of a culturally adapted digital tool for supporting optimal childrearing practices by Haley M LaMonica, Yun J. C. Song, Victoria Loblay, Mahalakshmi Ekambareshwar, Aila Naderbagi, Iqthyer Uddin Md Zahed, Jakelin Troy and Ian B. Hickie in DIGITAL HEALTH</p
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
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