1,721,139 research outputs found
Physiochemical characterization and coating of polyurethane with a new heparin adsorbing material
No full textThe coating of polyurethane devices was obtained by using a solution of a new heparin-adsorbing material. PUPA. The structure of the coated material was investigated at different depths by FTIR techniques. The bond with heparin is electrostatic, as revealed by subtracting the spectrum of the native PUPA from that of the heparinized sample
Conformation of human plasma proteins at polymer surfaces: the effectiveness of surface heparinization
No full textStudies were made on the adsorption of two human plasma proteins, albumin (HSA) and fibrinogen (HFg), onto three different polymeric surfaces: commercial pellethane R 2363-80AE (PU); pellethane crosslinked with a poly(amido-amine) (PUPA); and heparinized PUPA, using in situ ATR/FTIR spectroscopy (attenuated total reflection Fourier transform infrared spectroscopy). Conformational changes were found to occur on the two proteins upon adsorption onto bare PU and PUPA and the protein unfolding on bare PU was also found to be time dependent. On the contrary, the two proteins do not change conformation when they are adsorbed onto the heparinized surface, emphasising the effectiveness of surface heparinizatio
FTIR characterization of heparinizable polymer-coated materials for application in biomedicine
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FT-IR studies of protein adsorption on polymeric materials: influence of surface structure, hydrophobicity and charge
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Thermodynamic and FT-IR studies for the protonation of free and cellulose surface-grafted vinyl polymers carrying amido and carboxylic groups in the side chain
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