2,285 research outputs found

    The arms race

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    UPEI; [sound recording].; 2 sound cassette (137 min.); Panel members : Reginald Stuart ; Tom Trenton ; David MacDonald. Moderator : Kenneth Grant.; University of Prince Edward Island. World problems lecture series ; February 19, 1981

    Ruth McEnery Stuart

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    Subject: Formal portrait of Arkansas author Ruth McEnery Stuart. Gift of Ethel C. Simpson. 1. Stuart, Ruth McEnery. I. Simpson, Ethel C., donor

    Redemption in the work of Francis Stuart

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    The idea of redemption is central to an understanding of the work of Francis Stuart. Through an examination of its development and expression, it is possible to demonstrate the integrity of his work and its distinctive qualities. Such a demonstration is necessary because Stuart's writing has been subjected to comparatively little scholarly inquiry, although reviews of his work, especially that produced since 1949, suggest that it is impressive and important. First, a general background to Stuart's work, a discussion of the special problems associated with reading it, and a summary of his corpus is provided. This indicates that the idea of redemption is important to his earliest writing. The state of redemption is shown to be a necessary apotheosis for Stuart's outcast heroes; it involves spiritual suffering through which may be found a sense of reintegration and a higher reality. This is expressed through interrelated themes such as those of gambler, artist and ordinary man; mystic and criminal; sacred and profane love; and spirituality and the mundane. The nature of the redemptive experience is further elaborated by distinctive, complex motifs, especially the hare, the ark and the woman-Christ. Their recurrence provides an important element in the unity of Stuart's work. Because Stuart's idea of the outcast raises important biographical questions, an examination of the relationship between Stuart's life and his work is made. Finally, the way in which the idea of redemption exists in the language structures of Stuart's novels is examined, with especial reference to his most recent work, The High Consistory. The thesis shows that the development of the these of redemption demonstrates the integrity of Stuart's work

    13-valent pneumococcal conjugate vaccine (PCV13)

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    The thirteen valent pneumococcal conjugate vaccine (PCV13, Prevenar 13Ô) is the broader coverage successor to the highly effective seven valent vaccine (PCV7, PrevenarÔ) which has reduced rates of pneumococcal disease in many countries. Despite the success of PCV7, pneumococcal disease due to non-PCV7 serotypes remains a threat in many settings, in particular many developing countries with a high burden of pneumococcal disease where serotype 1 and 5 are among the most common serotypes. Disease due to certain non-PCV7 serotypes, in particular serotype 19A has also begun to increase in incidence in countries with widespread use of PCV7. PCV13 consists of thirteen pneumococcal capsular polysaccharides individually conjugated to the diphtheria-derived protein carrier CRM197. In addition to serotypes 4, 6B, 9V, 14, 18C, 19F and 23F included in PCV7, PCV13 also includes serotypes 1, 3, 5, 6A, 7F and 19A. PCV13 was licensed on the basis of non-inferiority trials and has proved to be at least as safe and effective as PCV7. PCV13 replaced PCV7 in the childhood immunisation schedules of the USA and UK in 2010 and is being rolled out to an increasing number of developing countries during 2011. Here we review the current literature regarding this vaccine, describing safety, efficacy, global serotype coverage and use and future directions

    John Stuart Mill’s projected science of society: 1827-1848

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    The purpose of the thesis is to examine John Stuart Mill’s political thought from about 1827 to 1848 as an exercise in intellectual history. It focuses, first, on Mill’s view, formulated by the late 1830s, that contemporary society was ‘civilized’, and second, on his project of a science of society, which he aspired to develop in the late 1830s and early 1840s. By the late 1830s, Mill came to the view that his contemporary society was a ‘commercial society or civilization’, dominated by the middle, commercial class. The first part of my thesis, constituted by Chapters 2-4, discusses the way in which Mill formed his notion of civilization, and what he meant by the term ‘civilization’. Mill paid attention to the implications of the rise of the middle class, and regarded such phenomena of contemporary society as the corruption of the commercial spirit and excessive social conformity as an inevitable consequence of the rise of the middle class. The second part of the thesis, constituted by Chapters 5-9, examines Mill’s projected science of society. In the late 1830s and early 1840s, Mill attempted to develop a new science of society whose subject-matter was the nature and prospects of commercial, civilized society. This aspiration culminated in A System of Logic, published in 1843. In examining Mill’s projected science, I pay particular attention to the fact that he conceived new sciences of history and of the formation of character, both of which were indispensable in his project, although he failed to give a complete account of these sciences. My thesis shows that the implications of his interest both in history and in the formation of character are more significant than Mill scholars have assumed

    After neo-liberalism: Republican democracy in new times

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    The financial crisis and resulting recession could mark the end of a political era defined by the dominance of 'neo-liberal' ideas. Stuart White asks: what will the new era look like? And what will be its agenda? Copyright (c) 2009 The Author. Journal compilation (c) 2009 ippr.

    Corrigendum: Pneumococcal vaccine impacts on the population genomics of non-typeable haemophilus influenzae: (Microbial Genomics 2021; 9, 10.1099/mgen.0.000209)

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    There was a change in the author names in the published article. The new list should read: David W. Cleary1,2, Vanessa T. Devine3, Denise E. Morris1, Karen L. Osman1, Rebecca A. Gladstone4, Stephen D. Bentley4, Saul N. Faust1,5, Stuart C. Clarke1,2,6 1Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK. 2NIHR Southampton Biomedical Research Centre, University Hospital Southampton Foundation NHS Trust, Southampton, UK. 3Northern Ireland Centre for Stratified Medicine and Clinical Translational Research Innovation Centre, Londonderry, UK. 4Pathogen Genomics, Wellcome Trust Sanger Institute, UK. 5NIHR Southampton Clinical Research Facility, University Hospital Southampton Foundation NHS Trust, Southampton, UK. 6Global Health Research Institute, University of Southampton, Southampton, UK.</p

    High pressure phase transformations in polycrystalline yttrium oxide

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    Numerous studies have been performed on high-pressure/high temperature phase transitions in rare-earth sesquioxides. Most of these studies were performed using diamond-anvil presses, which limits the size of samples that can be processed. Hence, studies of microstructural and properties changes accompanying phase transitions have been largely neglected. The purpose of this study has been to fill this gap, working with polycrystalline cubic-Y2O3 because of its importance in IR window and dome applications. We selected Diamond Materials Inc. as partner in this investigation, since this company has the expertise to make test pieces under well-controlled HPHT-processing conditions, thus ensuring that the results obtained for one batch of samples to the next are reproducible. This turned out to be crucial, since variations in applied pressure (1.0 to 8.0 GPa range), and holding times (seconds to hours), resulted in significant changes in observed micro/nano-structures. The temperature was fixed at 1000°C in order to limit HPHT-processing variables to pressure and holding time. In view of the results reported here, it now seems clear that extending the investigation to higher temperatures and lower pressures would be productive. The principal accomplishments of this research are as follows: (1) optimization of a reversible-phase transformation process to convert polycrystalline cubic-Y2O3 into the nanocrystalline state, involving a forward-phase transformation from cubic-to-monoclinic (c-to-m) Y2O3 at a high pressure (8.0 GPa) followed by a reverse-phase transformation from monoclinic-to-cubic (m-to-c) Y2O3 at a lower pressure (1.0 GPa); (2) discovery of a transformation-induced crystallization process to convert polycrystalline c-Y2O3 into columnar-grained m-Y2O3, and possibly into single-crystal m-Y2O3 - the driving force is attributed to a pressure-induced phase transformation that occurs at the tips of the growing columnar-grains; (3) formation of a mixed-phase (c-Y2O3/m-Y2O3) nanocomposite due to incomplete reverse transformation from m-to-c Y2O3 - a near 50:50 nanocomposite displays the highest hardness; and (4) insight into infiltration of carbon-containing gases (e.g. CO, CO2), formed via reactions between carbon heater and entrapped gases (e.g. O2, H2O) in the pressure cell, into cracked grain boundaries to form carbon particles/films via a vapor-deposition mechanism, and into uncracked grain boundaries to form carbon-rich species via a boundary-diffusion mechanism.Ph. D.Includes bibliographical referencesby Stuart Deutsc

    An Open Framework for Integrating Widely Distributed Hypermedia Resources

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    The success of the WWW has served as an illustration of how hypermedia functionality can enhance access to large amounts of distributed information. However, the WWW and many other distributed hypermedia systems offer very simple forms of hypermedia functionality which are not easily applied to existing applications and data formats, and cannot easily incorporate alternative functions which would aid hypermedia navigation to and from existing documents that have not been developed with hypermedia access in mind. This paper describes the extension to a distributed environment of the open hypermedia functionality of the Microcosm system, which is designed to support the provision of hypermedia access to a wide range of source material and application, and to offer straightforward extension of the system to incorporate new forms of information access
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