1,720,984 research outputs found
Laparoscopic conversion of MacLean vertical banded gastroplasty (VBG) to gastric bypass (GBP) with Higa GEA technique
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Ectopic breast cancer: case report and review of the literature.
No full textEctopic breast tissue comes in two forms: supernumerary and aberrant. Despite morphologic differences, ectopic breast tissue presents characteristics analogous to orthotopic breast tissue in terms of function and, most importantly, pathologic degeneration. Data in the literature concerning its precise incidence, the probability of malignant degeneration, and its standardized management are scarce and controversial. This study selected more than 100 years of literature, and this report discusses a case of ectopic breast cancer treatment, suggesting novel therapeutic advice that could bring considerable clinical advantages, improve cosmetic results, and reduce the psychological impact on patients
Effect of biliopancreatic diversion on hypertension in severely obese patients.
No full textHypertension is a medical disorder frequently associated with severe obesity, and
the effect of weight loss on the reduction of blood pressure has been well
established. In this study, the relationships between the weight loss surgically
obtained by biliopancreatic diversion and blood pressure were investigated in a
population of severely obese patients with preoperative hypertension. At 1 year
following the operation, blood pressure was normalized in more than half of
patients; in a further 10% of cases the hypertensive status resolved within the
3-year follow-up period. The resolution of hypertension was independently
associated with age and body weight and was unrelated to sex, the amount of
weight loss, or body fat distribution. In severely obese patients with
hypertension undergoing bariatric surgery, biliopancreatic diversion is advisable
since it achieves and supports the maintenance of body weight close to the ideal
value
Long-term effect of biliopancreatic diversion on blood pressure in hypertensive obese patients
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Liver damage in severely obese patients: a clinical-biochemical-morphologic study on 1,000 liver biopsies.
No full textBACKGROUND - Preoperative clinical and biochemical data and intraoperative liver biopsy of 1,000 obese patients submitted to biliopancreatic diversion (BPD) were analyzed, and correlations investigated.
METHODS - Of 2,645 patients submitted to BPD between May 1976 and November 2002, the last 1,000 consecutive obese patients with no history of alcohol consumption or infectious hepatitis were selected. Clinical data included: age, body weight, BMI, waist-to-hip ratio (W/H), arterial blood pressure, serum glucose, triglycerides, cholesterol, albumin/gamma-globulin ratio, total, conjugated and unconjugated bilirubin, gamma-GT, alkaline phosphatase, AST, ALT, and prothrombin time. The degree of steatosis, inflammation and fibrosis on intraoperative wedge liver biopsy was determined and scored. Liver steatosis >70% and presence of bridging fibrosis were analyzed separately.
RESULTS - Mean BMI was 48 kg/m(2). 263 patients had steatosis of >70%, and 79 had bridging fibrosis. Regression analysis showed an association between steatosis and AST, ALT, AST/ALT ratio, body weight, W/H, serum glucose, serum tryglicerides, BMI, gamma-GT, age, and unconjugated bilirubin. Inflammation was significantly greater in older patients. Patients with bridging fibrosis had significantly higher values of serum glucose, AST, gamma-GT, serum cholesterol and were significantly older. Bridging fibrosis was associated with diabetes, W/H >1, hypertension, albumin/gamma-globulin ratio <1.
CONCLUSION - Severe steatosis and bridging fibrosis seem to be associated with the metabolic syndrome. No reliable biochemical data could identify patients with severe chronic liver damage with sufficient sensitivity to avoid liver biopsy for diagnosis and staging of the disease
Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
No full textAbstract Introduction The frequency of intra-orbital metastasis in systemic cancer is a controversial topic. Of all metastatic tumors to the orbit of the eye, breast carcinoma is considered to be the most prevalent. Orbital findings typically present themselves after the diagnosis of the primary tumor, with an average delay of three to six years. In spite of that, this study reports a case in which orbital manifestation was the initial symptom in breast carcinoma diagnosis. Case presentation A 66-year-old Italian Caucasian woman presented with a swelling located on the lower orbit of her right eye. Conclusions Previous cases report orbital manifestations discovered secondary to breast cancer. This case demonstrates that orbital symptoms may be the primary presentation of the disease. Orbital metastasis originating from breast cancer predicts widespread metastatic disease in other organs. In the presence of an ambiguous infiltrative orbital process, diagnostic examination of the breast is recommended.</p
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