1,721,167 research outputs found
Modulation of exploratory behavior in female mice by protein-borne male urinary molecules
No full textMale pheromones are believed to attract females and repel male
mice in open field tests but, when tested in more complex environments, they can
attract male mice in usually avoided areas. Females were tested in an apparatus
with one dark and one light side, in the absence or presence of male urine
or the major urinary proteins (MUPs) bearing the natural ligands. Diestrous
females were slower in leaving from the dark area when male urine or MUPs
were present in it. Estrogen-primed females showed the opposite behavior, with
an increase in the same latency. The light-avoidance behavior of prepubertal
females, or females reared without males was not influenced by the presence of
male chemosignals. The results show that adult female mice can react to MUPborne
volatiles as to adult male urine and use them as cues of male mice, if they
were previously exposed to male cues during infancy. MUP-borne molecules
are, thus, the olfactory trace of males in the environment and modulate mice
exploratory behavior
Pathfinding to the olfactory bulb: the role of peripheral cues in addressing neural stem cells to the target
No full text
Clusters of cAMP-dependent protein kinase regulatory subunit RIalpha are present in a class of cholinergic neurons in the rat brain
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