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An Efficient Synthesis of 4-Aryl and 4-Vinylphenylalanines by Stille Cross-Coupling Reaction
No full textA Convenient Preparation of Selectively Protected L-DOPA derivatives from 3-iodo-L-Tyrosine
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Synthesis of 1,2-dithiolane analogues of leucine for potential use in peptide chemistry
No full text[GRAPHICS] 1,2-Dithiolanes present several points of interest for both peptide and medicinal chemistry, yet no chiral alpha-amino acids containing this five-membered heterocyclic system are available. We report here the first synthesis of N- and C-protected derivative of (S)-2-amino-3-(1,2-dithiolan4-yl)propionic acid (Adp) and its 1,3-dithiolic form
Synthesis of b-Substituted-butenolides through the Palladium-Catalyzed Reaction of Unsaturated Triflates and Halides with Methyl 4-Hydroxy-2-butenoate
No full text4-amino-1,2-dithiolane-4-carboxylic acid (Adt) as cysteine conformationally restricted analogue. Synthetic protocol for Adt containing peptides
No full textAn efficient and versatile protocol to incorporate the achiral and C-alpha,C-alpha-tetrasubstituted 4-amino-1,2-dithiolane-4-carboxylic acid Adt (1) residue into peptides is described. The 2,2-bis[(benzylthio)methyl]glycine N-carboxy anhydride (5) was found to be the key reactive intermediate from which both Boc-Adt-OMe (8) and the glutathione analogue H-Glu(-Adt-Gly-OH)-OH (12) can be obtained. (C) 2000 Elsevier Science Ltd. All rights reserved
Discussion Addendum for: Palladium-Catalyzed Reduction of Vinyl Trifluoromethanesulfonates to Alkenes: Cholesta-3,5-DieneOrganic Syntheses
No full textcholesta-3,5-diene
2,6-lutidine
1,1’-bis(diphenylphosphino)ferrocene
1,3-bis(diphenylphosphino)propane
1,3-bis(diphenylphosphino)butane
Pinacolborane
3-methyl-1-azatricyclo[5.2.1.0]decane
(–)-Galantamin
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