88,068 research outputs found

    Q&A: Professor Maurice Moloney

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    Professor Maurice Moloney is the new director and chief executive of Rothamsted Research. He has written more than 80 scientific papers and holds more than 300 patents in plant biotechnology worldwide. Professor Moloney is also a leading authority on plant cell biology, especially seed biology and its biotechnological applications in crop improvement. He is the 12th director of Rothamsted since 1843, succeeding Professor Ian Crute CBE, who retired from the institute in 200

    Moloney, J F, NX50177

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/405676Surname: MOLONEY. Given Name(s) or Initials: J F. Military Service Number or Last Known Location: NX50177. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 24556.243846 Item: [2016.0049.37953] "Moloney, J F, NX50177

    PROPAGATION OF A GAUSSIAN PULSE UNDER 2-PHOTON NEAR-RESONANT CONDITIONS

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    MOLONEY JV, Faisal F. PROPAGATION OF A GAUSSIAN PULSE UNDER 2-PHOTON NEAR-RESONANT CONDITIONS. JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS. 1980;13(10):2137-2146

    POSSIBILITY OF DIRECTLY OBSERVING AUTLER-TOWNES POWER SPLITTING OF CERTAIN ROTATIONAL LINES WITH AN INTENSE IR LASER

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    MOLONEY JV, Faisal F. POSSIBILITY OF DIRECTLY OBSERVING AUTLER-TOWNES POWER SPLITTING OF CERTAIN ROTATIONAL LINES WITH AN INTENSE IR LASER. OPTICS COMMUNICATIONS. 1979;29(1):62-66

    A note on loop-soliton solutions of the short-pulse equation

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    It is shown that the N-loop soliton solution to the short-pulse equation may be decomposed exactly into N separate soliton elements by using a Moloney-Hodnett type decomposition. For the case N = 2, the decomposition is used to calculate the phase shift of each soliton caused by its interaction with the other one. Corrections are made to some previous results in the literatur

    TIME-DEPENDENT THEORY OF NON-HERMITIAN SCHRODINGER-EQUATION - APPLICATION TO MULTIPHOTON-INDUCED IONIZATION DECAY OF ATOMS

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    Faisal F, MOLONEY JV. TIME-DEPENDENT THEORY OF NON-HERMITIAN SCHRODINGER-EQUATION - APPLICATION TO MULTIPHOTON-INDUCED IONIZATION DECAY OF ATOMS. JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS. 1981;14(19):3603-3620

    COMPUTATION OF MULTI-PHOTON IR-SPECTRA OF SMALL MOLECULES - APPLICATION TO CO

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    MOLONEY JV, Faisal F. COMPUTATION OF MULTI-PHOTON IR-SPECTRA OF SMALL MOLECULES - APPLICATION TO CO. JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS. 1979;12(17):2829-2840

    Teaching Transmedia Practice in a Design School

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    Transmedia Design practice is usually seen as a response to the contemporary mediascape and as an important element of communication curricula. The development of transmedia practice and the planning process of narrative worlds and their distribution across multiple channels has followed a ‘learning by doing’ approach. The practical dimension has often anticipated the theoretical one. However, if we seek to apply the potential of this discipline to areas beyond entertainment, it is necessary to develop a design practice model that derives from the professional world. While acknowledging the paramount role of transmedia practice in communication design, this chapter will discuss the Plug Social TV experience as an example of design methodology for conceiving transmedia communication strategies. We will present a refined approach for teaching transmedia design that includes the theory, process, and tools for design courses and workshops. Action research and in-field education activities, on and off the School of Design’s campus of Politecnico di Milano, have included multiple participants and perspectives. Design students, design researchers, citizens, and local associations met each other in academic or urban contexts for developing social dialogue and collaboration, weaving factual and fictional worlds

    Core-Binding Factor Influences the Disease Specificity of Moloney Murine Leukemia Virus

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    The core site in the Moloney murine leukemia virus (Moloney MLV) enhancer was previously shown to be an important determinant of the T-cell disease specificity of the virus. Mutation of the core site resulted in a significant shift in disease specificity of the Moloney virus from T-cell leukemia to erythroleukemia. We and others have since determined that a protein that binds the core site, one of the core-binding factors (CBF) is highly expressed in thymus and is essential for hematopoiesis. Here we test the hypothesis that CBF plays a critical role in mediating pathogenesis of Moloney MLV in vivo. We measured the affinity of CBF for most core sites found in MLV enhancers, introduced sites with different affinities for CBF into the Moloney MLV genome, and determined the effects of these sites on viral pathogenesis. We found a correlation between CBF affinity and the latent period of disease onset, in that Moloney MLVs with high-affinity CBF binding sites induced leukemia following a shorter latent period than viruses with lower-affinity sites. The T-cell disease specificity of Moloney MLV also appeared to correlate with the affinity of CBF for its binding site. The data support a role for CBF in determining the pathogenic properties of Moloney MLV

    Tolerance to viral antigens in Mov-13 mice carrying endogenized Moloney-murine leukemia virus.

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    In virus-positive (V+) C57BL/6 Mov-13 mice, Moloney-murine leukemia virus (M-MuLV) is integrated into the germ line and expressed early in lymphoid and nonlymphoid organs. The pattern of immune reactivity to viral antigens in these mice was studied and compared to that of their virus-negative (V-) counterparts. Using a radioimmuno-binding or -precipitation assay, V- mice showed good antibody production after challenge with Moloney-murine sarcoma virus (M-MSV), but no antibodies were detected in V+ mice. Moreover, Mov-13 V+ mice failed to generate virus-specific cytotoxic T lymphocytes (CTL) in secondary mixed-leukocyte tumor cell culture (MLTC) while V- mice showed a strong cytotoxic response. This lack of activity in mass V+ cultures was due to a very low frequency of CTL precursors which did not increase following in vivo challenge with M-MSV or in vitro stimulation with MBL-2 Moloney leukemia cell line. These findings indicate that early M-MuLV activation in Mov-13 V+ mice induces a state of tolerance to viral antigens involving both the humoral and cellular immune responses and related to the high incidence of T-cell lymphomas
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