1,753,142 research outputs found

    Caro mio ben

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    Side 1. 1. Caro mio ben ; 2. Smoke gets in your eyes ; 3. Atmosphere ; 4. Hope in China -- Side 2. 5. Piano pieces.by Nova. Hope in China. Atmosphere.Title supplied by cataloguer.Live recording (Except side 1 content no. 4).Possibly reproduced from other commercial recording or radio broadcast (Pending for review) (Side 1 content no. 4)"November 10號"--Audio content.Electronic reproduction from Rulan Chao Pian Audio Cassette Collection.Performers, unknown.Spoken in Chinese and English."November 10 hao"--Audio content

    A mio-inozitol kezelés fokozza a humán adipociták metabolikus aktivitását ex vivo

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    A barna/bézs adipocitákban kifejeződő uncoupling protein (UCP) 1 szétkapcsolja az elektron transzport-láncot és az ATP-szintézist. A belső mitokondriális membránon keresztül történő protoncsorgás következtében hő szabadul fel, mely folyamat során az adipociták nagy mennyiségben használnak fel tápanyagokat (pl. glükózt, zsírsavakat és aminosavakat). A munkacsoport korábban sejtpermeábilis dibutiril-cAMP (db-cAMP) analóggal modellezte a hideg hatására bekövetkező szimpatikus idegrendszeri választ adipocitákban, amelynek eredményeként nemcsak a termogenikus markerek, hanem a mio-inozitol transzportert kódoló SLC2A13 génjének kifejeződése is növekedett. A mio-inozitolról korábban leírták, hogy fokozza az anyagcsereaktivitást és az inzulinérzékenységet 2-es típusú diabéteszben szenvedőkben. Jelen vizsgálatban a mio-inozitol kezelés - nagy hőtermelő képességgel rendelkező - humán nyaki eredetű zsírsejtekre kifejtett hatását kívántuk feltérképezni. Primer nyaki szubkután és mély nyaki zsírszövet-eredetű sztróma sejteket érett adipocitákká differenciáltattunk 14 napon át, majd db-cAMP kezelést alkalmaztunk 10 órán keresztül mio inozitol jelenlétében vagy hiányában. Az SLC2A13, valamint a termogenikus gének és fehérjék kifejeződését RT-qPCR-ral és western blottal határoztuk meg. Az adipociták oxigénfogyasztását és extracelluláris acidifikációját Seahorse XF96 Extracellular Flux Analyzer-rel mértük. A karnitin-palmitoil transzferáz inhibitor Etomoxir (ETO) illetve az ATP szintáz gátló Oligomycin hozzáadását követően meghatároztuk az ETO-rezisztens, illetve a protoncsorgásos légzést, mely paraméterek a sejtek glükóz és aminosav felhasználásáról, illetve hőtermelő kapacitásáról adnak felvilágosítást. Mio-inozitol hatására növekedett a hőtermelésért felelős gének (UCP1, DIO2, PM20D1, CPT2 és KCNK3) kifejeződése, valamint a bazális ETO rezisztens és a protoncsorgásos oxigénfogyasztás nyaki szubkután és mély nyaki adipocitákban. A mio-inozitol azonban nem fokozta tovább a db-cAMP általi termogenikus aktivációt. Mio-inozitol jelenlétében emelkedett az adipociták extracelluláris acidifikációja, mely fokozott glikolízisre utalhat. Eredményeink arra utalnak, hogy a mio-inozitol fokozza a humán adipociták metabolikus aktivitását, mely új stratégiát nyithat az elhízás és az inzulinrezisztencia kezelésére.BSc/BAorvosi diagnosztikai analitikusmagyarOrvosdiagnosztikai laboratóriumi analitikanappaliTO kérte a bíráló nevének törlésé

    Premessa

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    Le riforme che hanno riguardato il sistema universitario si collocano nel quadro pi ampio e complesso del processo di rivisitazione della intera pubblica amministrazione italiana. Tale processo, avviatosi agli inizi degli anni Novanta, di fatto non si mai interrotto per effetto di molti provvedimenti che hanno riguardato i sistemi contabili, la governance, il controllo e la valutazione. Il GBS (Gruppo di studio per la ricerca scientifica sul Bilancio Sociale) con il volume presentato ha inteso contribuire al dibattito scientifico in atto sui temi della rendicontazione allargata o non-finanziaria e della governance, mettendo insieme competenze, studi ed esperienze di diversi ricercatori italiani che, per varie ragioni e da diverse prospettive, da tempo e con importanti risultati si occupano di “università”. Il lavoro riesce a raccogliere analisi e prospettive scientificamente rilevanti in grado di testimoniare una esigenza continua di approfondimento di grande importanza per il nostro Paese

    sj-pdf-2-mio-10.1177_20597991221077911 – Supplemental material for The ecology of human behavior: A network perspective

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    Supplemental material, sj-pdf-2-mio-10.1177_20597991221077911 for The ecology of human behavior: A network perspective by Rafael Quintana in Methodological Innovations</p

    The SDGs, firm’s boundaries, and the role of accounting. Mindful ecosystems as the new value generating entity

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    In this chapter, we argue that, following the SDGs, the boundaries of value-generating entities need to be redefined. We propose the construct of a mindful ecosystem as the relevant value-generating entity and we discuss its implications in terms of decision making and accounting. The decision-making activities in mindful ecosystems do not take place only at the firm level (short-term and local focus) but also at the ecosystem level (long-term and global focus). This evolution of the boundaries of the value-generating entity has relevant implications from an accounting perspective as well and more specifically in terms of the content and form of the report

    sj-docx-1-mio-10.1177_20597991221077911 – Supplemental material for The ecology of human behavior: A network perspective

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    Supplemental material, sj-docx-1-mio-10.1177_20597991221077911 for The ecology of human behavior: A network perspective by Rafael Quintana in Methodological Innovations</p

    sj-pdf-1-mio-10.1177_20597991241240081 – Supplemental material for A novel experimental vignette methodology: SMART vignettes

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    Supplemental material, sj-pdf-1-mio-10.1177_20597991241240081 for A novel experimental vignette methodology: SMART vignettes by Jane Paik Kim and Hyun-Joon Yang in Methodological Innovations</p

    Proceedings of the 8th European Conference on Intellectual Capital

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    These proceedings represent the work of presenters at the 8th European Conference on Intellectual Capital (ECIC 2016). This year the conference is being hosted by Ca' Foscari University of Venice, Italy on the 12-13 May 2016. The Conference Co-Chairs are Professor Carlo Bagnoli and Professor Chiara Mio from Ca' Foscari University of Venice and the Programme Co-Chairs are Prof Andrea Garlatti and Dr Maurizio Massaro from Udine University, Italy. The opening keynote address is by James Guthrie from the University of Sydney, Australia on A structured literature review of the intellectual capital research literature. The second day Keynote is being presented by John Dumay from Macquarie University, Sydney, Australia on the topic of “Involuntary disclosure of Intellectual Capital: Is it relevant?”. The primary aim of this conference is to contribute to the further advancement of intellectual capital theory and practice. The conference provides a platform for presenting findings and ideas for the intellectual capital community and associated fields. The range of people, issues and the mix of approaches followed will ensure an interesting two days. 143 abstracts were received for this conference. After the double blind, peer review process there are 41 Academic Research Papers, 7 PhD Papers and 3 Masters Research Papers and 1 Work in Progress Paper published in these Conference Proceedings. These papers represent truly global research from some 31 different countries, including Australia, Austria, Bahrain, Belgium, Canada, China, Croatia, Czech Republic, Finland, France, Greece, Hong Kong, Hungary, Iran, Ireland, Italy, Kazakhstan, Latvia, Lithuania, Malaysia, México, New Zealand, Poland, Portugal, Romania, Russia, Slovakia, Spain, UK, Uruguay, and USA. We hope that you have an enjoyable conference. Carlo Bagnoli, Chiara Mio, Andrea Garlatti and Maurizio Massaro May 201

    El poema de Mio Cid (un comentario)

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    My research is a philological commentary of a fragment of the Cantar de Mio Cid. I study the text problems, and the external structure - rhyme, formulistic dictions, dialogue, etc. - After, I study the internal structure - temps, tense, adjective, semantic structures, syntax, etc. Finally I examine any interesting words

    The Routledge Handbook of Accounting for the Sustainable Development Goals

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    The introduction of Agenda 2030 and its 17 Sustainable Development Goals (SDGs) has traced a path for private and public entities interested in pursuing sustainable development. This handbook identifies the recent challenges in accounting research and the SDGs by exploring the evolutionary pathways and future direction of sustainability reporting. It explores the role of businesses as contributors to Agenda 2030 by assuming a multidisciplinary approach and provides a measure of organisations' contributions to the SDGs through the understanding of business strategies and policies on Agenda 2030 integration. The book represents a substantial and multi-faceted contribution to the debate on SDGs accounting by assembling international scholars and practitioners to effectively explore the practice and theory revolving around the current state of the art and highlight future research pathways. By providing a comprehensive evaluation of accounting for the Sustainable Development Goals, this volume will appeal to a wide variety of readers, from students, scholars, researchers, practitioners and policymakers interested in increasing their awareness of Agenda 2030 and offers a significant contribution to the evolution of accounting practices
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