148 research outputs found
Exposure to Methamphetamine and Phencyclidine during Development and Subsequent Behavioral Change
No full textA thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Takehiro Minamoto on December 2, 2005
Effect of memory load on eye movement control: A study using the reading span test
No full textAzuma Miyuki, Minamoto Takehiro, Yaoi Ken, et al. Effect of memory load on eye movement control: A study using the reading span test. Journal of Eye Movement Research 7, (2014); https://doi.org/10.16910/jemr.7.5.3
High working memory performers have efficient eye movement control systems under Reading Span Test
No full textAzuma Miyuki, Ikeda Takashi, Minamoto Takehiro, et al. High working memory performers have efficient eye movement control systems under Reading Span Test. Journal of Eye Movement Research 5, (2012); https://doi.org/10.16910/jemr.5.3.1
High working memory performers have efficient eye movement control systems under Reading Span Test
No full textAzuma Miyuki, Ikeda Takashi, Minamoto Takehiro, et al. High working memory performers have efficient eye movement control systems under Reading Span Test. Journal of Eye Movement Research 5, (2012); https://doi.org/10.16910/jemr.5.3.1
Effect of memory load on eye movement control: A study using the reading span test
No full textAzuma Miyuki, Minamoto Takehiro, Yaoi Ken, et al. Effect of memory load on eye movement control: A study using the reading span test. Journal of Eye Movement Research 7, (2014); https://doi.org/10.16910/jemr.7.5.3
Moderate sedation induced by general anaesthetics disrupts audio-spatial feature binding with sustained P3 components in healthy humans
No full textMinamoto Takehiro, Ikeda Takashi, Kang Hongling, et al. Moderate sedation induced by general anaesthetics disrupts audio-spatial feature binding with sustained P3 components in healthy humans. Neuroscience of Consciousness 2018, 876 (2018); https://doi.org/10.1093/nc/niy002.Feature binding is considered to be the basis for conscious stimulus perception, while anaesthetics exert a gradient effect on the loss of consciousness (LOC). By integrating these two streams of research, the present study assessed the effect of two anaesthetic agents (i.e. propofol and midazolam) on audio-spatial feature binding. We also recorded the electrophysiological activity of the frontal channels. Using pharmacokinetic simulation, we determined the effect-site concentration (Ce) of the anaesthetics at loss of response to verbal command and eyelash reflex. We subsequently adjusted Ce to 75%, 50% and 25% of Ce-LOC to achieve deep, moderate and light sedation, respectively. Behavioural results showed that moderate sedation selectively disrupted feature binding. The frontal channels showed a P3 component (350–600 ms peristimulus period) following the presentation of audio-spatial stimuli at baseline and under moderate and light sedations. Critically, the late event-related potential component (600–1000 ms) returned to the pre-activated level (0–350 ms) at baseline and under light sedation but was sustained under moderate sedation. We propose that audio-spatial feature binding may require the presence of a P3 component and its subsequent and sufficient decline, as under anaesthetic-induced moderate sedation the P3 component was sustained and featured binding was impaired
Moderate sedation induced by general anaesthetics disrupts audio-spatial feature binding with sustained P3 components in healthy humans
No full textMinamoto Takehiro, Ikeda Takashi, Kang Hongling, et al. Moderate sedation induced by general anaesthetics disrupts audio-spatial feature binding with sustained P3 components in healthy humans. Neuroscience of Consciousness 2018, 876 (2018); https://doi.org/10.1093/nc/niy002.Feature binding is considered to be the basis for conscious stimulus perception, while anaesthetics exert a gradient effect on the loss of consciousness (LOC). By integrating these two streams of research, the present study assessed the effect of two anaesthetic agents (i.e. propofol and midazolam) on audio-spatial feature binding. We also recorded the electrophysiological activity of the frontal channels. Using pharmacokinetic simulation, we determined the effect-site concentration (Ce) of the anaesthetics at loss of response to verbal command and eyelash reflex. We subsequently adjusted Ce to 75%, 50% and 25% of Ce-LOC to achieve deep, moderate and light sedation, respectively. Behavioural results showed that moderate sedation selectively disrupted feature binding. The frontal channels showed a P3 component (350–600 ms peristimulus period) following the presentation of audio-spatial stimuli at baseline and under moderate and light sedations. Critically, the late event-related potential component (600–1000 ms) returned to the pre-activated level (0–350 ms) at baseline and under light sedation but was sustained under moderate sedation. We propose that audio-spatial feature binding may require the presence of a P3 component and its subsequent and sufficient decline, as under anaesthetic-induced moderate sedation the P3 component was sustained and featured binding was impaired
How two brains make one synchronized mind in the inferior frontal cortex: FNIRS-based hyperscanning during cooperative singing
No full textOsaka N., Minamoto T., Yaoi K., et al. How two brains make one synchronized mind in the inferior frontal cortex: FNIRS-based hyperscanning during cooperative singing. Frontiers in Psychology 6, 1811 (2015); https://doi.org/10.3389/fpsyg.2015.01811.One form of communication that is common in all cultures is people singing together. Singing together reflects an index of cognitive synchronization and cooperation of human brains. Little is known about the neural synchronization mechanism, however. Here, we examined how two brains make one synchronized behavior using cooperated singing/humming between two people and hyperscanning, a new brain scanning technique. Hyperscanning allowed us to observe dynamic cooperation between interacting participants. We used functional near-infrared spectroscopy (fNIRS) to simultaneously record the brain activity of two people while they cooperatively sang or hummed a song in face-to-face (FtF) or face-to-wall (FtW) conditions. By calculating the inter-brain wavelet transform coherence between two interacting brains, we found a significant increase in the neural synchronization of the left inferior frontal cortex (IFC) for cooperative singing or humming regardless of FtF or FtW compared with singing or humming alone. On the other hand, the right IFC showed an increase in neural synchronization for humming only, possibly due to more dependence on musical processing
Serial changes of humor comprehension for four-frame comic Manga: An fMRI study
No full textOsaka M., Yaoi K., Minamoto T., et al. Serial changes of humor comprehension for four-frame comic Manga: An fMRI study. Scientific Reports 4, 5828 (2014); https://doi.org/10.1038/srep05828.Serial changes of humor comprehension evoked by a well organized four-frame comic Manga were investigated by fMRI in each step of humor comprehension. The neural substrates underlying the amusing effects in response to funny and mixed order manga were compared. In accordance with the time course of the four frames, fMRI activations changed serially. Beginning with the second frame (development scene), activation of the temporo-parietal junction (TPJ) was observed, followed by activations in the temporal and frontal areas during viewing of the third frame (turn scene). For the fourth frame (punch line), strong increased activations were confirmed in the medial prefrontal cortex (MPFC) and cerebellum. Interestingly, distinguishable activation differences in the cerebellum between funny and non-funny conditions were also found for the fourth frame. These findings suggest that humor comprehension evokes activation that initiates in the TPJ and expands to the MPFC and cerebellum at the convergence level
Extrapunitive and intropunitive individuals activate different parts of the prefrontal cortex under an ego-blocking frustration
No full textMinamoto T., Osaka M., Yaoi K., et al. Extrapunitive and intropunitive individuals activate different parts of the prefrontal cortex under an ego-blocking frustration. PLoS ONE 9, e86036 (2014); https://doi.org/10.1371/journal.pone.0086036.Different people make different responses when they face a frustrating situation: some punish others (extrapunitive), while others punish themselves (intropunitive). Few studies have investigated the neural structures that differentiate extrapunitive and intropunitive individuals. The present fMRI study explored these neural structures using two different frustrating situations: an ego-blocking situation which blocks a desire or goal, and a superego-blocking situation which blocks self-esteem. In the ego-blocking condition, the extrapunitive group (n = 9) showed greater activation in the bilateral ventrolateral prefrontal cortex, indicating that these individuals prefer emotional processing. On the other hand, the intropunitive group (n = 9) showed greater activation in the left dorsolateral prefrontal cortex, possibly reflecting an effortful control for anger reduction. Such patterns were not observed in the superego-blocking condition. These results indicate that the prefrontal cortex is the source of individual differences in aggression direction in the ego-blocking situation
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