3,750 research outputs found
Kainic acid neurotoxicity in the goldfish opic tectum. No protection by the NMDA receptor antagonist MK801 and partial protection by abolition of a tectal excitatory input
No full textMotivi letterari nei libri per l’infanzia di Paolo Di Paolo
No full textThe article, organised in the form of a discussion, aims to analyse the themes and motifs of Paolo Di Paolo’s works that are addressed to young audiences. The author has recently published a large number of volumes directed just at younger readers. When beholding the titles that constitute the author’s bibliography, the reader is struck by Di Paolo’s predisposition to transform literary classics: as much in Giacomo il signor bambino as in the edition of the Divina Commedia, the author’s goal is to try to reach his new readers. Therefore, Di Paolo proves to be a prolific author of the genre; in fact, in his bibliography, volumes of fairy tales with a classic slant, such as La mucca volante, are listed as well.L’articolo contiene un’analisi di temi e di motivi delle opere di Paolo Di Paolo dirette al pubblico più piccolo. L’autore negli ultimi anni ha pubblicato un cospicuo numero di volumi indirizzati, infatti, proprio ai lettori più giovani. Ciò che stupisce scorgendo i titoli che costituiscono la bibliografia dell’autore, è la predisposizione a trasformare i classici della letteratura: tanto in Giacomo il signor bambino quanto nell’edizione della Divina Commedia l’obiettivo è cercare di raggiungere i lettori più giovani. Di Paolo si dimostra, quindi, un autore prolifico del genere, tant’è che nell’elenco non mancano volumi fiabeschi dal taglio classico come La mucca volante. Analizzare le opere giovanili dello scrittore costituisce un fatto inedito
Induction of brain ornithine decarboxilase after systemic or intrastriatal administration of kainic acid
No full textProtection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitters and glial markers
No full text
Regional and cellular distribution of ephrin-B1 in adult mouse brain
No full textThe membrane-bound proteins ephrins and their receptors, Eph receptor tyrosine kinases, are
known for their key role during development of the central nervous system (CNS). Ligand/
receptor interactions as a result of cell–cell contacts activate intracellular signalling pathways
which mediate specific cellular responses. Activation can occur bidirectionally in both the
receptor and the ligand-bearing cells. Eph receptor and ephrin families have been implicated
in synaptic plasticity in themature brain: effects include long-term potentiation/depression of
excitatory transmission (LTP/LTD) and an action on the structure and number of synaptic
contacts. However, due to the redundancy of binding between receptors and ligands, the role
of individual proteins has not yet been completely elucidated. Ephrin-B1 has been suggested
to play a role in synaptic plasticity in the hippocampus, but its expression and localization at
pre- or post-synaptic sites has been poorly documented, most likely due to the apparent low
activity of the corresponding gene in mature brain. Here we present immunohistochemical
data demonstrating a broad but highly regulated cellular distribution of ephrin-B1 in the
mature mouse brain. We show that ephrin-B1 is expressed post-synaptically on dendritic
spines in the cortex, supporting a role in synaptic plasticity in this region. However, the
prevalent extra-synaptic distribution in regions such as the hippocampus and cerebellum
suggests an additional structural role, perhaps at the neuron/glia interface
Pier Paolo Pasolini e la società: il "sogno di una cosa" travolto dalla "nuova preistoria"
No full textL’articolo prende in esame – nel centenario della nascita – il “pensiero politico” di Pier Paolo Pasolini. Vengono pertanto scandagliati (soprattutto) i suoi scritti sulla società, ma frequenti sono le incursioni nella letteratura e soprattutto nel cinema di questo autore del tutto originale. Ne emerge lo spessore di concetti spesso usati dal poeta per analizzare e criticare il presente: Nuova Preistoria, nuovo capitalismo, consumismo, edonismo, il Potere, il Palazzo, il Processo, sviluppo e progresso, sacralità in primis. Si evidenzia inoltre come l’occhio e il giudizio di Pasolini siano stati principalmente guidati dalla passione e solo di rimando dalla ragione. Un ruolo non secondario nella sua percezione del reale ha inoltre assunto la sua omosessualità. Nella parte finale dello scritto si analizzano alcuni strumenti tecnici utilizzati dall’autore per svolgere la propria opera di comprensione del presente e della sua conseguente traduzione artistico-critica.The article examines - in the centenary of his birth - the "political thought" of Pier Paolo Pasolini.
Therefore, it scrutinizes (above all) his writings on society, but there are frequent incursions into the literature and especially into the cinema of this completely original author. What emerges is the depth of concepts often used by the poet to analyze and criticize the present: New Prehistory, new capitalism, consumerism, hedonism, Power, the Palace, the Process, development and progress, sacredness in primis. It also shows how Pasolini's eye and judgment were mainly guided by passion and only by reason. His homosexuality also played a significant role in his perception of reality. In the final part of the paper we analyze some technical tools used by the author to carry out his work of understanding the present and its consequent artistic-critical translation
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