23 research outputs found

    SYSTEMATIC AND CONTROLLED FORMULATION OF ORGANIC NANOCARRIERS

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    Ph.DDOCTOR OF PHILOSOPHY (FOE

    Nanoparticles of Organic Electronic Materials for Biomedical Applications

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    10.1021/acsnano.0c02651ACS NANO1489228-924

    What Eshu has to do with the school?

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    O presente trabalho está inserido no campo dos estudos da temática da Lei Federal 10.639/03, correlacionando-a especificamente com a disciplina de Sociologia ofertada no ensino médio. Sendo assim, esta pesquisa diz respeito aos aspectos do orixá Exu, nos cultos das religiões afro-brasileiras, principalmente no Candomblé, na Umbanda.. O objetivo geral desta dissertação foi investigar a possibilidade de abordagem dos aspectos do orixá Exu como conteúdo específico da disciplina de Sociologia do ensino médio, tendo como referência a Lei Federal 10.639/03, e as Diretrizes Curriculares da Educação Básica dessa disciplina no Estado do Paraná. Os objetivos específicos da presente dissertação foram: compreender em que medida a antropologia evolucionista contribuiu para o desenvolvimento do racismo e da intolerância aos povos africanos, afro-brasileiros e suas culturas; compreender a influência da escola evolucionista nos estudos antropológicos brasileiros e entender o processo de mudanças de paradigmas da antropologia brasileira. Buscando a validade empírica da presente dissertação, fundamentamos a metodologia na teoria de Weber (2001), visto que concordamos com o autor em relação ao modo de investigação dos fenômenos sociais, tentando aplicá-lo para compreensão do fenômeno social em questão. Utilizamos vários procedimentos, dentre eles a pesquisa bibliográfica (documentários, seleção de livros, artigos e leis) e a elaboração de um roteiro de entrevistas estruturadas, com questões abertas, direcionadas aos professores, à direção e aos pedagogos da coordenação de colégios do ensino básico. Nesta pesquisa, consideramos o quanto a educação deve contribuir para desfazer o mal-entendido que ocorreu com o orixá Exu, sob pena de continuarmos como uma visão racista sobre Exu e as religiões afro-brasileiras. Nesse âmbito, apresentamos ao leitor algumas das pesquisas mais importantes sobre Exu. O diferencial de nossa pesquisa está na demonstração da relação entre Exu e a Lei 10.639/03, evidenciando que é possível abordar o tema como conteúdo específico, fundamentado também nas diretrizes curriculares da disciplina de Sociologia do estado do Paraná. A contribuição da presente pesquisa também se efetiva nas sugestões de como seria possível relacionar Exu com os conteúdos específicos da disciplina em questão. Foram realizadas nove entrevistas com professores do ensino médio, de várias disciplinas, de colégios estaduais (alguns ministram aulas em mais de um colégio) da Região Metropolitana de Maringá, norte do Paraná, durante o mês de novembro do ano de 2015. As respostas desses profissionais proporcionaram o conhecimento das dificuldades que os professores enfrentam ao abordarem temas relacionados às religiões afro-brasileiras nas aulas, mas nos revelaram, principalmente, maneiras de abordar os aspectos do orixá Exu como conteúdo específico.This work is inserted in the field of thematic studies of Federal Law 10.639/03. correlating specifically with Sociology discipline offered in high school. Therefore, this research concerns the aspects of Orisha Eshu, the cults of the african-Brazilian religions, especially Candomblé and Umbanda..The general objective of this work was to investigate the possibility of approaching aspects of Orisha Eshu as specific content of high school sociology discipline, with reference to the Federal Law 10,639 / 03 and the Curriculum Guidelines for Basic Education of the discipline in the state of Paraná. The specific objectives of this dissertation were: to understand to what measure evolutionary anthropology contributed to the development of racism and intolerance to African people, african-Brazilians and their cultures; understand the influence of evolutionary school in the Brazilian anthropological studies and understand the process of paradigm shifts of Brazilian anthropology. Seeking the empirical validity of this dissertation, we base the methodology in Weber's theory (2001), as agreed with the author in relation to the social phenomenon research mode, trying to apply it to understanding the social phenomenon in question. We use several procedures, including literature searches (documentaries, selection of books, articles and laws) and the elaboration of a guide for structured interviews with open questions, directed to teachers, the direction and pedagogues of coordination of basic education schools. In this research, we consider how education should help dispel the misunderstanding that occurred with the Orisha Eshu, otherwise continue as an racist view of Eshu and african-Brazilian religions. In this context, we present the reader with some of the most important research on Eshu. The differential of our research is the demonstration of the relation between Exu and Law 10.639/03, showing that it is possible to approach the theme as specific content, also based on the curriculum guidelines of the discipline of the state of Paraná Sociology. The research contribution is also actualize in suggestions for how could relate Eshu with the specific contents of the subject in question. Nine interviews were conducted with high school teachers in several disciplines, state schools (some give classes in more than one school) the metropolitan region of Maringa, north of Paraná, during the month of November 2015. The responses of these professionals provided the knowledge of the difficulties that teachers face in addressing issues related to african-Brazilian religions in class, but mainly revealed in ways to address aspects of the Orisha Eshu as specific content

    Solvent Magic for Organic Particles

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    10.1021/acsnano.9b01487ACS NANO1332675-2680complete

    That bright & beautiful day

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    A magic realist novel narrated by Eshu, the Yoruba god of language and myth, about coming of age in the contemporary anti-war movement, and of the terrible tragedy that leads him to tell the tale.M.F.A.A novelby Martin Wile

    Microfluidics-Prepared Uniform Conjugated Polymer Nanoparticles for Photo-Triggered Immune Microenvironment Modulation and Cancer Therapy

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    Photothermal therapy (PTT) has shown great promise to spatiotemporally ablate cancer cells, and further understanding of the immune system response to PTT treatment would contribute to improvement in therapeutic outcomes. Herein, we utilize microfluidic technology to prepare biocompatible conjugated polymer nanoparticles (CP NPs) as PTT agents and assess the immune response triggered by CP-based PTT treatment in vitro and in vivo. Through careful control of the antisolvent, CP NPs with a uniform diameter of 52 nm were obtained. The c-RGD-functionalized CP NPs exhibit high photothermal conversion efficiency, inducing effective cancer cell death under an 808 nm laser illumination. Using macrophage cells as the model, CP NPs demonstrate effective activation of proinflammatory immune response. Furthermore, in tumor-bearing mice model, a single round of CP NP-assisted PTT could efficiently induce antitumor immunity activation and ultimately inhibit tumor growth. The study provides detailed understanding of both microfluidic technology for CP NP fabrication and photothermal-triggered antitumor immune responses
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